fluorodeoxyuridylate has been researched along with Leukemia L 1210 in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (77.27) | 18.7374 |
| 1990's | 5 (22.73) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balzarini, J; Bentrude, WG; Béres, J; De Clercq, E; Kálmán, A; Párkányi, L | 1 |
| Balzarini, J; Bentrude, WG; Béres, J; De Clercq, E; Otvös, L; Sági, G | 1 |
| Gaumont, Y; Hsiao, MC; Kalman, TI; Kisliuk, RL; Nair, IG; Nair, MG; Nanavati, NT | 1 |
| Ajmera, S; Bapat, AR; Danenberg, K; Danenberg, PV | 1 |
| Balzarini, J; De Clercq, E; Hunston, RN; Jones, AS; McGuigan, C; Walker, RT | 1 |
| Balińska, M; Bretner, M; Dzik, JM; Kulikowski, T; Rode, W; Shugar, D | 1 |
| Bertino, JR; Fernandes, DJ; Moroson, BA | 1 |
| Cadman, E; Grant, S | 1 |
| Cadman, E; Dreyer, R | 1 |
| Au, JL; Danhauser, L; Luccioni, C; Rustum, YM | 1 |
| Cadman, E; Heimer, R | 1 |
| Bretner, M; Cieśla, J; Dzik, JM; Kulikowski, T; Rode, W; Shugar, D; Zieliński, Z | 1 |
| Bretner, M; Dzik, JM; Gołos, B; Jarmuła, A; Kulikowski, T; Poznański, J; Rode, W; Shugar, D | 1 |
| Danhauser, L; Rustum, YM; Wang, G | 1 |
| Santi, DV; Washtien, WL | 1 |
| Fernandes, DJ; Klubes, P; Mandel, HG | 1 |
| Fernandes, DJ; Klubes, P | 1 |
| Anderson, T; Chabner, BA; Murinson, DS; Myers, CE; Schwartz, HS | 1 |
| Cerna, I; Connelly, K; Klubes, P; Mandel, HG | 1 |
| Keyomarsi, K; Moran, RG | 1 |
| Bretner, M; Cieśla, J; Dzik, JM; Kierdaszuk, B; Kulikowski, T; Rode, W; Shugar, D; Zieliński, Z | 1 |
| Ciesla, J; Dzik, JM; Kulikowski, T; Rode, W; Shugar, D; Zielinski, Z | 1 |
1 review(s) available for fluorodeoxyuridylate and Leukemia L 1210
| Article | Year |
|---|---|
Determinants of response to antimetabolites and their modulation by normal purine and pyrimidine metabolites.
Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; DNA, Neoplasm; Fluorodeoxyuridylate; Fluorouracil; Humans; Leukemia L1210; Neoplasms; Neoplasms, Experimental; Thymidine; Thymidylate Synthase; Uridine | 1981 |
21 other study(ies) available for fluorodeoxyuridylate and Leukemia L 1210
| Article | Year |
|---|---|
Synthesis, structure, and antitumor and antiviral activities of a series of 5-halouridine cyclic 3',5'-monophosphates.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Humans; Leukemia L1210; Mice; Molecular Conformation; Nucleotides, Cyclic; Protein Kinases; Rabbits; Simplexvirus; Structure-Activity Relationship; Uracil Nucleotides; Uridine Monophosphate; Vaccinia virus; X-Ray Diffraction | 1986 |
Synthesis and antitumor and antiviral properties of 5-halo- and 5-(trifluoromethyl)-2'-deoxyuridine 3',5'-cyclic monophosphates and neutral triesters.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Line; Deoxyuracil Nucleotides; Drug Evaluation, Preclinical; Humans; Hydrocarbons, Halogenated; Indicators and Reagents; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Simplexvirus; Structure-Activity Relationship; Vaccinia virus; Vesicular stomatitis Indiana virus | 1986 |
Folate analogues. 26. Syntheses and antifolate activity of 10-substituted derivatives of 5,8-dideazafolic acid and of the poly-gamma-glutamyl metabolites of N10-propargyl-5,8-dideazafolic acid (PDDF).
Topics: Animals; Chemical Phenomena; Chemistry; Folic Acid; Folic Acid Antagonists; Lacticaseibacillus casei; Leukemia L1210; Quinazolines; Streptococcus; Structure-Activity Relationship; Thymidylate Synthase | 1986 |
Synthesis and biological activity of 5-fluoro-2',3'-dideoxy-3'-fluorouridine and its 5'-phosphate.
Topics: Animals; Cell Division; Deoxyuracil Nucleotides; Dideoxynucleosides; Dideoxynucleotides; Floxuridine; Indicators and Reagents; Kinetics; Leukemia L1210; Lung Neoplasms; Methyltransferases; Mice; Pentosyltransferases; Thymidine Phosphorylase; Thymidylate Synthase | 1984 |
Synthesis and biological properties of some cyclic phosphotriesters derived from 2'-deoxy-5-fluorouridine.
Topics: Animals; Antimetabolites, Antineoplastic; Bromodeoxyuridine; Deoxycytidine; Deoxyuridine; Drug Resistance; Indicators and Reagents; Leukemia L1210; Mice; Organophosphorus Compounds; Structure-Activity Relationship; Thymidine; Thymidine Monophosphate | 1984 |
2-Thio derivatives of dUrd and 5-fluoro-dUrd and their 5'-monophosphates: synthesis, interaction with tumor thymidylate synthase, and in vitro antitumor activity.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Binding, Competitive; Carcinoma, Ehrlich Tumor; Cell Division; Deoxyuracil Nucleotides; Drug Screening Assays, Antitumor; Floxuridine; Kinetics; Leukemia L1210; Mice; Spectrophotometry; Stereoisomerism; Structure-Activity Relationship; Thiouridine; Thymidylate Synthase; Tumor Cells, Cultured | 1993 |
The role of methotrexate and dihydrofolate polyglutamates in the enhancement of fluorouracil action by methotrexate.
Topics: Animals; Cell Line; Cell Survival; Drug Administration Schedule; Drug Therapy, Combination; Fluorodeoxyuridylate; Fluorouracil; Folic Acid; Folic Acid Antagonists; Leukemia L1210; Methotrexate; Mice; Polyglutamic Acid; Pteroylpolyglutamic Acids; Thymidylate Synthase | 1981 |
Modulation of 1-beta-D-arabinofuranosylcytosine metabolism and cytotoxicity in L1210 cells by fluoropyrimidine pretreatment.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Cell Line; Cell Survival; Clone Cells; Cytarabine; Deoxyribonucleotides; Deoxyuridine; Drug Interactions; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Leukemia L1210; Mice; Uridine | 1982 |
Use of periodate and methylamine for the quantitation of intracellular 5-fluoro-2'-deoxyuridine-5'-monophosphate by high-performance liquid chromatography.
Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Freeze Drying; Leukemia L1210; Methylamines; Mice; Oxidation-Reduction; Periodic Acid | 1981 |
Analysis of the thymidylate synthetase ternary complex by high-performance liquid steric exclusion chromatography.
Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Fluorodeoxyuridylate; Leukemia L1210; Methyltransferases; Mice; Protein Conformation; Tetrahydrofolates; Thymidylate Synthase | 1981 |
Interaction with 2(4)-thio-5-fluoro-dUMP of thymidylate synthases with differing sensitivities to 5-fluoro-dUMP.
Topics: Animals; Drug Resistance; Fluorodeoxyuridylate; Hymenolepis; Kinetics; Leukemia L1210; Liver Regeneration; Mice; Rats; Species Specificity; Thionucleotides; Thymidylate Synthase | 1993 |
Synthesis and interactions with thymidylate synthase of 2,4-dithio analogues of dUMP and 5-fluoro-dUMP.
Topics: Animals; Binding Sites; Cell Division; Deoxyuracil Nucleotides; Drug Resistance, Neoplasm; Enzyme Inhibitors; Floxuridine; Fluorodeoxyuridylate; Kinetics; Leukemia L1210; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Phosphorylation; Phosphotransferases; Protein Binding; Thionucleotides; Thymidylate Synthase; Tumor Cells, Cultured | 1996 |
Selectivity of action of 5-FU: biochemical basis.
Topics: Animals; Colonic Neoplasms; Drug Resistance; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Humans; Leukemia L1210; Mice; Mice, Inbred Strains; Rats; RNA, Neoplasm; Thymidine; Uridine | 1979 |
Assay of intracellular free and macromolecular-bound metabolites of 5-fluorodeoxyuridine and 5-fluorouracil.
Topics: Animals; Chromatography, Gel; Culture Techniques; Cytosol; Deoxyuracil Nucleotides; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Kinetics; Leukemia L1210; Rats; RNA; Thymidine Kinase | 1979 |
Studies of the antitumor action of 5-fluorouracil (FU).
Topics: Animals; Antineoplastic Agents; Bone Marrow; Carcinoma 256, Walker; Colonic Neoplasms; Deoxyuridine; DNA; Drug Resistance; Fluorodeoxyuridylate; Fluorouracil; Humans; Intestine, Small; Leukemia L1210; Mice; Rats; Ribosomes | 1979 |
A biochemical and pharmacological study of therapeutic synergism with 5-fluorouracil plus cyclophosphamide in murine L1210 leukemia.
Topics: Animals; Body Weight; Bone Marrow; Cyclophosphamide; DNA, Neoplasm; Drug Synergism; Drug Therapy, Combination; Fluorodeoxyuridylate; Fluorouracil; Leukemia L1210; Male; Mice; Mice, Inbred Strains | 1979 |
Competitive binding radioassay for 5-fluorodeoxyuridine 5'-monophosphate in tissues.
Topics: Animals; Binding, Competitive; Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Fluorouracil; Half-Life; Leukemia L1210; Mice; Radioligand Assay; Thymidylate Synthase | 1979 |
Effects of 5-fluorouracil on 5-fluorodeoxyuridine 5'-monophosphate and 2-deoxyuridine 5'-monophosphate pools, and DNA synthesis in solid mouse L1210 and rat Walker 256 tumors.
Topics: Animals; Bone Marrow; Carcinoma 256, Walker; Deoxyuracil Nucleotides; Deoxyuridine; DNA, Neoplasm; Drug Resistance; Fluorodeoxyuridylate; Fluorouracil; Intestine, Small; Leukemia L1210; Male; Mice; Mice, Inbred Strains; Rats | 1978 |
Quinazoline folate analogs inhibit the catalytic activity of thymidylate synthase but allow binding of 5-fluorodeoxyuridylate.
Topics: Animals; Binding Sites; Cytidine Monophosphate; Floxuridine; Fluorodeoxyuridylate; Folic Acid; Folic Acid Antagonists; Kinetics; Leukemia L1210; Mice; Models, Structural; Protein Binding; Quinazolines; Structure-Activity Relationship; Thymidylate Synthase | 1990 |
Mechanism of inhibition of mammalian tumor and other thymidylate synthases by N4-hydroxy-dCMP, N4-hydroxy-5-fluoro-dCMP, and related analogues.
Topics: Animals; Binding Sites; Binding, Competitive; Carcinoma, Ehrlich Tumor; Deoxycytidine Monophosphate; Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Hymenolepis; Kinetics; Leukemia L1210; Liver; Liver Regeneration; Mice; Neoplasms, Experimental; Rats; Thymidylate Synthase; Tumor Cells, Cultured | 1990 |
Interaction of 5-fluoro-4-thio-2'-deoxyuridine 5'-phosphate with mammalian tumour thymidylate synthase: role of the pyrimidine N(3)-H dissociation.
Topics: Animals; Carcinoma, Ehrlich Tumor; Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Humans; Hydrogen-Ion Concentration; Kinetics; Leukemia L1210; Leukemia, Lymphoid; Mice; Neoplasm Proteins; Thionucleotides; Thymidylate Synthase | 1987 |