fluorodeoxyuridylate has been researched along with Colorectal Cancer in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (57.14) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, J; Huang, L | 1 |
| Bré, J; Czekster, CM; Dickson, AL; Harrison, DJ; McKissock, FG; Mullen, P; Read, OJ; Tang, P; Zhang, Y; Zickuhr, GM | 1 |
| Guo, J; Huang, L; Liu, Y; Sun, D; Yu, Z; Zou, Y | 1 |
| Ayabe, H; Fukushima, M; Haseba, M; Hidaka, S; Nakagoe, T; Sawai, T; Tagawa, Y; Tsuji, T; Yamaguchi, H; Yano, H; Yasutake, T | 1 |
| Hirano, K; Kanehira, E; Kawakami, K; Kawashima, S; Nagasato, A; Omura, K; Shirasaka, T; Tawaraya, K; Watanabe, S; Watanabe, Y | 1 |
| Hoekman, K; Meijer, S; Peters, GJ; Pinedo, HM; Smid, K; van der Wilt, CL; van Groeningen, CJ | 1 |
| Kok, RM; Lankelma, J; Meyer, S; Noordhuis, P; Peters, GJ; Pinedo, HM; van der Wilt, CL; van Groeningen, CJ | 1 |
| Adachi, I; Hashimoto, T; Ishida, F; Kawakami, K; Matsu, T; Omura, K; Watanabe, Y | 1 |
| Anderson, J; Gmeiner, WH; Kolar, C; Kolath, J; Lawson, T; Liu, J; Skradis, A; Talmadge, J | 1 |
| Anderson, J; Gmeiner, WH; Kolar, C; Kolath, J; Lawson, TA; Liu, J; Talmadge, J | 1 |
| Gmeiner, WH; Kolar, C; Lawson, TA; Liu, J | 1 |
| Griffiths, JR; Howe, FA; Lofts, F; McIntyre, DJ; McSheehy, PM; Nicholson, G; Noordhuis, P; Peters, GJ; Price, NM; Rodrigues, LM; Smid, K; Stubbs, M; Wadsworth, P | 1 |
| Fujiwara, Y; Nishio, K; Ohe, Y; Ohmori, T; Saijo, N; Sugimoto, Y | 1 |
| Sasaki, T | 1 |
2 review(s) available for fluorodeoxyuridylate and Colorectal Cancer
| Article | Year |
|---|---|
Formulation of two lipid-based membrane-core nanoparticles for FOLFOX combination therapy.
Topics: Animals; Carcinoma, Hepatocellular; Colorectal Neoplasms; Fluorodeoxyuridylate; Fluorouracil; Lipids; Liposomes; Liver Neoplasms; Nanoparticles; Oxaliplatin; Polyethylene Glycols | 2022 |
[High-dose leucovorin and 5-FU].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Evaluation; Fluorodeoxyuridylate; Fluorouracil; Humans; Leucovorin; Stomach Neoplasms; Thymidylate Synthase | 1992 |
12 other study(ies) available for fluorodeoxyuridylate and Colorectal Cancer
| Article | Year |
|---|---|
The novel anti-cancer fluoropyrimidine NUC-3373 is a potent inhibitor of thymidylate synthase and an effective DNA-damaging agent.
Topics: Antimetabolites; Colorectal Neoplasms; DNA; Enzyme Inhibitors; Fluorodeoxyuridylate; Fluorouracil; Humans; Thymidylate Synthase | 2023 |
Two nanoformulations induce reactive oxygen species and immunogenetic cell death for synergistic chemo-immunotherapy eradicating colorectal cancer and hepatocellular carcinoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Carcinoma, Hepatocellular; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Drug Compounding; Drug Synergism; Female; Fluorodeoxyuridylate; Fluorouracil; Immunogenic Cell Death; Immunotherapy; Leucovorin; Liver Neoplasms; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasm Metastasis; Organoplatinum Compounds; Reactive Oxygen Species; Tissue Distribution | 2021 |
Chromosomal imbalances associated with acquired resistance to fluoropyrimidines in human colorectal cancer cells.
Topics: Antimetabolites, Antineoplastic; Chromosome Aberrations; Colorectal Neoplasms; DNA, Neoplasm; Drug Resistance, Neoplasm; Fluorodeoxyuridylate; Fluorouracil; Humans; Nucleic Acid Hybridization; Tumor Cells, Cultured | 2003 |
The number of 5-fluoro-2'-deoxyuridine-5'-monophosphate binding sites and reduced folate pool in human colorectal carcinoma tissues: changes after tegafur and uracil treatment.
Topics: Base Sequence; Binding Sites; Colorectal Neoplasms; Fluorodeoxyuridylate; Humans; Molecular Sequence Data; RNA, Messenger; Tegafur; Tetrahydrofolates; Thymidylate Synthase; Uracil | 1995 |
Potentiation of 5-fluorouracil induced inhibition of thymidylate synthase in human colon tumors by leucovorin is dose dependent.
Topics: Binding Sites; Colonic Neoplasms; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Synergism; Fluorodeoxyuridylate; Fluorouracil; Humans; Kinetics; Leucovorin; Thymidylate Synthase | 1993 |
Prolonged retention of high concentrations of 5-fluorouracil in human and murine tumors as compared with plasma.
Topics: Adult; Aged; Animals; Colorectal Neoplasms; Female; Fluorodeoxyuridylate; Fluorouracil; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Injections, Intravenous; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Middle Aged; Species Specificity | 1993 |
[Changes of the number of FdUMP binding sites of thymidylate synthase and folate pools in human colorectal carcinomas following the administration of tegafur and uracil: preliminary report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Binding Sites; Colorectal Neoplasms; Fluorodeoxyuridylate; Folic Acid; Humans; Tegafur; Thymidylate Synthase; Uracil | 1993 |
Increased cytotoxicity and decreased in vivo toxicity of FdUMP[10] relative to 5-FU.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Biotransformation; Body Weight; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Drug Resistance, Neoplasm; Enzyme Inhibitors; Fibroblasts; Fluorodeoxyuridylate; Fluorouracil; Half-Life; Humans; Lethal Dose 50; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Orotate Phosphoribosyltransferase; Prodrugs; Thymidine Kinase; Thymidylate Synthase; Tumor Cells, Cultured | 1999 |
Positive interaction between 5-FU and FdUMP[10] in the inhibition of human colorectal tumor cell proliferation.
Topics: Antimetabolites, Antineoplastic; Cell Division; Colorectal Neoplasms; Drug Synergism; Fluorodeoxyuridylate; Fluorouracil; Humans; Prodrugs; Tumor Cells, Cultured | 1999 |
Targeted drug delivery to chemoresistant cells: folic acid derivatization of FdUMP[10] enhances cytotoxicity toward 5-FU-resistant human colorectal tumor cells.
Topics: Antineoplastic Agents; Carrier Proteins; Colorectal Neoplasms; Drug Delivery Systems; Drug Resistance, Neoplasm; Fluorodeoxyuridylate; Fluorouracil; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Membrane Proteins; Membrane Transport Proteins; Receptors, Cell Surface; RNA, Messenger; Thymidylate Synthase; Tumor Cells, Cultured | 2001 |
Issues of normal tissue toxicity in patient and animal studies--effect of carbogen breathing in rats after 5-fluorouracil treatment.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Biological Availability; Bone Marrow; Carbon Dioxide; Carcinoma, Transitional Cell; Colonic Neoplasms; Colorectal Neoplasms; Combined Modality Therapy; Fatal Outcome; Female; Fluorine Radioisotopes; Fluorodeoxyuridylate; Fluorouracil; Humans; Intestine, Small; Leucovorin; Liver; Liver Neoplasms; Magnetic Resonance Imaging; Middle Aged; Neoplasms, Multiple Primary; Oxygen; Rats; Rats, Inbred WF; Sigmoid Neoplasms; Tomography, X-Ray Computed; Ultrasonography; Urinary Bladder Neoplasms | 2001 |
In vitro enhancement of fluoropyrimidine-induced cytotoxicity by leucovorin in colorectal and gastric carcinoma cell lines but not in non-small-cell lung carcinoma cell lines.
Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Cell Survival; Colony-Forming Units Assay; Colorectal Neoplasms; Drug Synergism; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Leucovorin; Lung Neoplasms; Stomach Neoplasms; Tetrahydrofolates; Thymidylate Synthase; Tumor Cells, Cultured | 1992 |