fluorodeoxyuridylate has been researched along with Adenocarcinoma in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (65.22) | 18.7374 |
| 1990's | 7 (30.43) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Corbett, TH; Heidelberger, C; Moran, RG; Shahinian, AH; Spears, CP | 1 |
| Houghton, JA; Houghton, PJ | 1 |
| Houghton, JA; Houghton, PJ; Schmidt, C | 1 |
| Morin, J; Wolberg, WH | 1 |
| Houghton, JA; Houghton, PJ; Maroda, SJ; Phillips, JO | 1 |
| Kuiper, CM; Peters, GJ; Pinedo, HM; Rustum, YM; Smid, K; Van der Wilt, CL; Van Laar, JA | 1 |
| Fujimaki, M; Katuyama, S; Kuroki, Y; Okamoto, M; Sakamoto, T; Tazawa, K; Yamashita, I | 1 |
| Anderson, J; Gmeiner, WH; Kolar, C; Kolath, J; Lawson, T; Liu, J; Skradis, A; Talmadge, J | 1 |
| Griffiths, JR; Howe, FA; Lofts, F; McIntyre, DJ; McSheehy, PM; Nicholson, G; Noordhuis, P; Peters, GJ; Price, NM; Rodrigues, LM; Smid, K; Stubbs, M; Wadsworth, P | 1 |
| Ardalan, B; Cooney, D; Macdonald, JS; Schein, PS | 1 |
| Ardalan, B; Buscaglia, MD; Schein, PS | 1 |
| Fujiwara, Y; Nishio, K; Ohe, Y; Ohmori, T; Saijo, N; Sugimoto, Y | 1 |
| Hoshi, A; Iigo, M; Nishikata, K | 1 |
| Hoshi, A; Iigo, M; Nakajima, Y | 1 |
| Allegra, CJ; Boarman, D; Chu, E; Zinn, S | 1 |
| Houghton, JA; Houghton, PJ; Radparvar, S | 1 |
| Houghton, JA; Houghton, PJ; Torrance, PM; Weiss, KD; Williams, LG | 1 |
| Berne, M; Bernstein, L; Frösing, R; Gustavsson, BG; Hayes, AA; Spears, CP | 1 |
| Carlsson, G; Frösing, R; Gustavsson, BG; Spears, CP | 1 |
| Houghton, JA; Houghton, PJ; Radparvar, S; Torrance, PM; Williams, LG | 2 |
| Almersjö, O; Berne, M; Gustavsson, B; Spears, CP; Waldenström, J | 1 |
| Almersjö, O; Berne, MH; Frösing, R; Gustavsson, BG; Spears, PC | 1 |
23 other study(ies) available for fluorodeoxyuridylate and Adenocarcinoma
| Article | Year |
|---|---|
In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Drug Resistance; Fluorodeoxyuridylate; Fluorouracil; Injections, Intraperitoneal; Kinetics; Methyltransferases; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; RNA; Thymidylate Synthase; Time Factors | 1982 |
On the mechanism of cytotoxicity of fluorinated pyrimidines in four human colon adenocarcinoma xenografts maintained in immune-deprived mice.
Topics: Adenocarcinoma; Animals; Cell Survival; Colonic Neoplasms; Female; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Humans; Male; Mice; Mice, Inbred CBA; Neoplasm Transplantation; Neoplasms, Experimental; Transplantation, Heterologous; Uridine | 1980 |
The effect of derivatives of folic acid on the fluorodeoxyuridylate-thymidylate synthetase covalent complex in human colon xenografts.
Topics: Adenocarcinoma; Animals; Cell Line; Colonic Neoplasms; Deoxyuracil Nucleotides; Female; Fluorodeoxyuridylate; Folic Acid; Homocysteine; Humans; Methyltransferases; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Rectal Neoplasms; Tetrahydrofolates; Thymidylate Synthase; Transplantation, Heterologous; Vitamin B 12 | 1982 |
Thymidylate synthetase activity and fluorouracil sensitivity of human colonic cancer and normal mucosal tissue preparations.
Topics: Adenocarcinoma; Colon; Colonic Neoplasms; Deoxyuracil Nucleotides; Dose-Response Relationship, Drug; Fluorodeoxyuridylate; Fluorouracil; Humans; Methyltransferases; Mucous Membrane; Thymidylate Synthase | 1981 |
Biochemical determinants of responsiveness to 5-fluorouracil and its derivatives in xenografts of human colorectal adenocarcinomas in mice.
Topics: Adenocarcinoma; Animals; Cell Line; Colonic Neoplasms; Fluorodeoxyuridylate; Fluorouracil; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Rectal Neoplasms; Tetrahydrofolates; Thymidylate Synthase; Transplantation, Heterologous | 1981 |
Tumor size and origin determine the antitumor activity of cisplatin or 5-fluorouracil and its modulation by leucovorin in murine colon carcinomas.
Topics: Adenocarcinoma; Animals; Antidotes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Drug Interactions; Female; Fluorodeoxyuridylate; Fluorouracil; Immunosuppressive Agents; Leucovorin; Mice; Mice, Inbred BALB C; Weight Loss | 1996 |
Inhibitory effects of fluorinated pyrimidines, 5'-DFUR, UFT and T-506, in a model of hepatic metastasis of mouse colon 26 adenocarcinoma-assessment of inhibitory activity and adverse reactions at the maximum tolerated dose.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Body Weight; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Combinations; Female; Floxuridine; Fluorodeoxyuridylate; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Tegafur; Uracil | 1997 |
Increased cytotoxicity and decreased in vivo toxicity of FdUMP[10] relative to 5-FU.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Biotransformation; Body Weight; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Drug Resistance, Neoplasm; Enzyme Inhibitors; Fibroblasts; Fluorodeoxyuridylate; Fluorouracil; Half-Life; Humans; Lethal Dose 50; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Orotate Phosphoribosyltransferase; Prodrugs; Thymidine Kinase; Thymidylate Synthase; Tumor Cells, Cultured | 1999 |
Issues of normal tissue toxicity in patient and animal studies--effect of carbogen breathing in rats after 5-fluorouracil treatment.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Biological Availability; Bone Marrow; Carbon Dioxide; Carcinoma, Transitional Cell; Colonic Neoplasms; Colorectal Neoplasms; Combined Modality Therapy; Fatal Outcome; Female; Fluorine Radioisotopes; Fluorodeoxyuridylate; Fluorouracil; Humans; Intestine, Small; Leucovorin; Liver; Liver Neoplasms; Magnetic Resonance Imaging; Middle Aged; Neoplasms, Multiple Primary; Oxygen; Rats; Rats, Inbred WF; Sigmoid Neoplasms; Tomography, X-Ray Computed; Ultrasonography; Urinary Bladder Neoplasms | 2001 |
Studies on mechanisms of 5-fluorouracil resistance in murine and human tumors.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Drug Resistance; Fluorodeoxyuridylate; Fluorouracil; Humans; In Vitro Techniques; Mice; Neoplasms; Neoplasms, Experimental; Phosphorylation; Uracil Nucleotides | 1979 |
Tumor 5-fluorodeoxyuridylate concentration as a determinant of 5-fluorouracil response.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Deoxyuracil Nucleotides; DNA, Neoplasm; Fluorodeoxyuridylate; Fluorouracil; Kinetics; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasms, Experimental | 1978 |
In vitro enhancement of fluoropyrimidine-induced cytotoxicity by leucovorin in colorectal and gastric carcinoma cell lines but not in non-small-cell lung carcinoma cell lines.
Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Cell Survival; Colony-Forming Units Assay; Colorectal Neoplasms; Drug Synergism; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Leucovorin; Lung Neoplasms; Stomach Neoplasms; Tetrahydrofolates; Thymidylate Synthase; Tumor Cells, Cultured | 1992 |
In vivo antitumor effects of fluoropyrimidines on colon adenocarcinoma 38 and enhancement by leucovorin.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Biotransformation; Cell Division; Colonic Neoplasms; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Leucovorin; Male; Mice; Mice, Inbred Strains; Thymidylate Synthase; Uridine | 1992 |
Antitumor effect and tumor level of 5-fluoro-2'-deoxyuridylate following oral administration of tetradecyl 2'-deoxy-5-fluoro-5'-uridylate.
Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; Colonic Neoplasms; Fluorodeoxyuridylate; Fluorouracil; Injections, Intravenous; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mice, Nude; Neoplasms, Experimental | 1992 |
Interaction of gamma interferon and 5-fluorouracil in the H630 human colon carcinoma cell line.
Topics: Adenocarcinoma; Cell Division; Colonic Neoplasms; DNA; Drug Interactions; Drug Resistance; Fluorodeoxyuridylate; Fluorouracil; Folic Acid; Humans; Interferon-gamma; RNA; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Tumor Cells, Cultured | 1990 |
Effect of polyglutamylation of 5,10-methylenetetrahydrofolate on the binding of 5-fluoro-2'-deoxyuridylate to thymidylate synthase purified from a human colon adenocarcinoma xenograft.
Topics: Adenocarcinoma; Colonic Neoplasms; Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Folic Acid; Humans; In Vitro Techniques; Kinetics; Pteroylpolyglutamic Acids; Structure-Activity Relationship; Tetrahydrofolates; Thymidylate Synthase | 1989 |
Relationship between 5-fluoro-2'-deoxyuridylate, 2'-deoxyuridylate, and thymidylate synthase activity subsequent to 5-fluorouracil administration, in xenografts of human colon adenocarcinomas.
Topics: Adenocarcinoma; Adenosine Monophosphate; Animals; Cell Line; Colonic Neoplasms; Deoxyuracil Nucleotides; Drug Resistance; Fluorodeoxyuridylate; Fluorouracil; Humans; Hydrogen-Ion Concentration; Mice; Neoplasm Transplantation; Phosphoric Monoester Hydrolases; Thymidylate Synthase; Transplantation, Heterologous | 1986 |
Mechanisms of innate resistance to thymidylate synthase inhibition after 5-fluorouracil.
Topics: Adenocarcinoma; Breast Neoplasms; Colonic Neoplasms; Deoxyuracil Nucleotides; Drug Resistance; Fluorodeoxyuridylate; Fluorouracil; Humans; Pancreatic Neoplasms; Stomach Neoplasms; Thymidylate Synthase | 1988 |
Pharmacodynamics of 5-fluorouracil and leucovorin.
Topics: Adenocarcinoma; Animals; Bone Marrow; Colonic Neoplasms; Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Fluorouracil; Humans; Intestinal Mucosa; Leucovorin; Liver; Pancreatic Neoplasms; Rats; Rats, Inbred Strains; Rectal Neoplasms; Stomach Neoplasms; Thymidylate Synthase | 1988 |
Determination of thymidylate synthase activity in colon tumor tissues after treatment with 5-fluorouracil.
Topics: Adenocarcinoma; Charcoal; Colonic Neoplasms; Fluorodeoxyuridylate; Fluorouracil; Humans; Thymidylate Synthase | 1987 |
Concurrent allopurinol and 5-fluorouracil: 5-fluoro-2'-deoxyuridylate formation and thymidylate synthase inhibition in rat colon carcinoma and in regenerating rat liver.
Topics: Adenocarcinoma; Allopurinol; Animals; Colonic Neoplasms; Deoxyuracil Nucleotides; Female; Fluorodeoxyuridylate; Fluorouracil; Liver; Liver Regeneration; Male; Rats; Rats, Inbred Strains; Thymidylate Synthase; Time Factors | 1987 |
Sequential methotrexate/5-FU: FdUMP formation and TS inhibition in a transplantable rodent colon adenocarcinoma.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Deoxyuracil Nucleotides; Drug Interactions; Female; Fluorodeoxyuridylate; Fluorouracil; Kinetics; Male; Methotrexate; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Thymidylate Synthase | 1986 |
Binding of 5-fluorodeoxyuridylate to thymidylate synthase in human colon adenocarcinoma xenografts.
Topics: Adenocarcinoma; Animals; Cell Line; Colonic Neoplasms; Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Humans; Kinetics; Mice; Mice, Nude; Neoplasm Transplantation; Thymidylate Synthase; Transplantation, Heterologous | 1986 |