fluorocholine and Neurofibromatosis-1

fluorocholine has been researched along with Neurofibromatosis-1* in 2 studies

Other Studies

2 other study(ies) available for fluorocholine and Neurofibromatosis-1

ArticleYear
Diverse Behavior in 18F-Fluorocholine PET/CT of Brain Tumors in Patients With Neurofibromatosis Type 1.
    Clinical nuclear medicine, 2019, Volume: 44, Issue:8

    Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder that causes CNS tumors in around 20% of patients, being pilocytic astrocytomas (PA), and particularly optic pathway gliomas (OPG), the most common. We present three cases of NF1 patients referred for F-fluorocholine PET/CT because of suspected glioma in the setting of ongoing FUMEGA (Functional and Metabolic Glioma Analysis) trial. One case turned out to be a WHO grade I ganglioglioma; the second was a high grade glioma; and the last one (negative in PET) a probable low-grade glioma.

    Topics: Adult; Brain Neoplasms; Choline; Humans; Male; Neoplasm Grading; Neurofibromatosis 1; Positron Emission Tomography Computed Tomography

2019
Brain F-18 Fluorocholine PET/CT for the assessment of optic pathway glioma in neurofibromatosis-1.
    Clinical nuclear medicine, 2010, Volume: 35, Issue:10

    A 22-year-old man diagnosed with neurofibromatosis-I was admitted to the neurology department because of progressive hemianopsia and chronic headache. Magnetic resonance imaging, magnetic resonance spectroscopy (MRS), and F-18 fluorocholine revealed a splenial mass with imaging features compatible with malignant astrocytoma. At follow-up examination, the sharp decrease in F-18 fluorocholine uptake and in choline/creatine ratio supported a conservative management. Molecular imaging of optic pathway gliomas may be a valuable tool in the selection of therapeutic options.

    Topics: Brain; Choline; Glioma; Humans; Male; Neurofibromatosis 1; Optic Nerve; Positron-Emission Tomography; Tomography, X-Ray Computed; Young Adult

2010