fluorocholine has been researched along with Hyperplasia* in 2 studies
2 other study(ies) available for fluorocholine and Hyperplasia
| Article | Year |
|---|---|
False-positive result in 18F-fluorocholine PET/CT due to incidental and ectopic parathyroid hyperplasia.
PET/CT with F-fluorocholine (a positron-labeled choline analog) is currently used as a diagnostic tool for restaging prostate cancer patients with increasing prostate-specific antigen. We present an unusual case of a false-positive result using F-fluorocholine PET/CT because of incidental and ectopic parathyroid hyperplasia. Topics: Choline; False Positive Reactions; Humans; Hyperplasia; Incidental Findings; Male; Middle Aged; Multimodal Imaging; Parathyroid Glands; Positron-Emission Tomography; Prostatic Neoplasms; Tomography, X-Ray Computed | 2014 |
¹⁸F-Fluorocholine PET/CT for localization of hyperfunctioning parathyroid tissue in primary hyperparathyroidism: a pilot study.
Primary hyperparathyroidism is a common endocrine disorder which is diagnosed biochemically and for which therapy is surgical. A prerequisite for minimally invasive surgery, which minimizes morbidity and cost, is accurate localization of the involved gland(s). The aim of this study was to evaluate the usefulness of (18)F-fluorocholine PET/CT for preoperative localization of hyperfunctioning parathyroid tissue.. (18)F-Fluorocholine PET/CT and conventional parathyroid scintigraphic imaging consisting of (99m)Tc-sestaMIBI SPECT/CT, (99m)Tc-sestaMIBI dual-phase imaging and (99m)Tc-sestaMIBI/pertechnetate subtraction imaging were performed in 24 patients. The diagnostic performance of the imaging methods was compared against histology as the gold standard and postoperative serum Ca(2+) and iPTH values.. The sensitivity and specificity of (18)F-fluorocholine PET/CT were 92% and 100%, respectively, in contrast to 49% and 100%, 46% and 100%, and 44% and 100% for (99m)Tc-sestaMIBI SPECT/CT, (99m)Tc-sestaMIBI/pertechnetate subtraction imaging and (99m)Tc-sestaMIBI dual-phase imaging, respectively. Combined conventional scintigraphic imaging had a sensitivity and specificity of 64% and 100%, respectively. The performance of (18)F-fluorocholine PET/CT was superior particularly in patients with multiple lesions or hyperplasia.. (18)F-Fluorocholine PET/CT appears to be a promising, effective imaging method for localization of hyperfunctioning parathyroid tissue. Topics: Adult; Aged; Choline; Female; Follow-Up Studies; Humans; Hyperparathyroidism, Primary; Hyperplasia; Male; Middle Aged; Multimodal Imaging; Parathyroid Glands; Parathyroid Neoplasms; Pilot Projects; Positron-Emission Tomography; Tomography, X-Ray Computed | 2014 |