Page last updated: 2024-08-22

fluorine and Alzheimer Disease

fluorine has been researched along with Alzheimer Disease in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19908 (33.33)18.7374
1990's2 (8.33)18.2507
2000's4 (16.67)29.6817
2010's7 (29.17)24.3611
2020's3 (12.50)2.80

Authors

AuthorsStudies
Dai, Y; Fang, T; Jiang, T; Qiao, J; Xu, Y1
Burgos, CF; Castillo, C; F de la Torre, A; Fuentealba, J; Jiménez, CA; López, JJ; Sáez-Orellana, F; Sánchez, Y1
Dabur, M; Loureiro, JA; Pereira, MC1
Hirao, K; Ibrahim, NF; Kato, T; Morikawa, S; Shirai, N; Sogabe, T; Taguchi, H; Tooyama, I; Yanagisawa, D1
Banner, DW; Bergadano, A; David-Pierson, P; Fischer, H; Guba, W; Hilpert, H; Hochstrasser, R; Humm, R; Jacobsen, H; Krummenacher, D; Kuglstatter, A; Mauser, H; Mayweg, AV; Muser, T; Narquizian, R; Ozmen, L; Pinard, E; Polara, A; Rogers-Evans, M; Schnider, C; Woltering, TJ; Wostl, W1
de Backer, M; de Jongh, S; Jiskoot, W; Kapoerchan, VV; Metaxas, A; Nabuurs, RJ; Overhand, M; Overkleeft, HS; van Buchem, MA; van der Weerd, L; Welling, MM; Windhorst, AD1
Coelho, MA; Gomes, B; Loureiro, JA; Pereira, Mdo C1
Hirao, K; Ibrahim, NF; Inubushi, T; Kato, T; Morikawa, S; Shirai, N; Sogabe, T; Taguchi, H; Tooyama, I; Yanagisawa, D1
Forsback, S; Haaparanta-Solin, M; Kaasalainen, M; La Ferla, B; Lopez-Picon, F; Masserini, M; Nicotra, F; Re, F; Rinne, JO; Rokka, J; Salonen, J; Snellman, A; Solin, O; Zona, C1
Khosravan, A; Marani, S; Sadeghi Googheri, MS1
Aksinenko, AY; Makhaeva, GF; Richardson, RJ; Serebryakova, OG; Sokolov, VB1
Abid, M; Foster, M; Hailemichael, S; Sood, A; Török, B; Török, M1
Beswick, P; Charrier, N; Clarke, B; Demont, E; Dingwall, C; Dunsdon, R; Faller, A; Gleave, R; Hawkins, J; Hussain, I; Johnson, CN; MacPherson, D; Maile, G; Matico, R; Milner, P; Mosley, J; Naylor, A; O'Brien, A; Redshaw, S; Riddell, D; Rowland, P; Skidmore, J; Smith, KJ; Soleil, V; Stanway, S; Stemp, G; Stuart, A; Sweitzer, S; Theobald, P; Vesey, D; Walter, DS; Ward, J; Wayne, G1
Creasey, H; Cutler, NR; Duara, R; Grady, CL; Haxby, JV; Rapoport, SI; Schapiro, MB1
Kameyama, M; Kuhl, DE; Metter, EJ; Phelps, ME; Riege, WH1
Brant-Zawadzki, M; Budinger, TF; Friedland, RP; Jagust, WJ1
Budinger, TF; Derenzo, SE; Friedland, RP; Ganz, E; Huesman, RH; Koss, B; Mathis, CA; Ober, BA; Yano, Y1
Benson, DF; Cummings, JL; Hawkins, RA; Kuhl, DE; Phelps, ME; Tsai, SY1
Agwani, N; Forbes, WF1
Williams, DR1
Majamaa, K; Mannermaa, RM; Oikarinen, J; Tarkka, T; Yli-Mäyry, N1
Ando, K; Yokoi, F1
Benson, DF1
Friedland, RP; Jagust, WJ; Koss, E; Ober, BA1

Reviews

5 review(s) available for fluorine and Alzheimer Disease

ArticleYear
Fluorinated Molecules and Nanotechnology: Future 'Avengers' against the Alzheimer's Disease?
    International journal of molecular sciences, 2020, Apr-23, Volume: 21, Issue:8

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Drug Development; Drug Discovery; Fluorine; Humans; Molecular Targeted Therapy; Nanomedicine; Nanotechnology; Protein Aggregates; Structure-Activity Relationship; Theranostic Nanomedicine

2020
The Potential Effect of Fluorinated Compounds in the Treatment of Alzheimer's Disease.
    Current pharmaceutical design, 2015, Volume: 21, Issue:39

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Fluorine; Humans; Molecular Conformation; Neuroprotective Agents

2015
Amyloid imaging using fluorine-19 magnetic resonance imaging ((19)F-MRI).
    Ageing research reviews, 2016, Volume: 30

    Topics: Alzheimer Disease; Amyloidosis; Animals; Fluorine; Humans; Magnetic Resonance Imaging; Multimodal Imaging; Plaque, Amyloid; Positron-Emission Tomography; Styrenes

2016
Chemical speciation applied to bio-inorganic chemistry.
    Journal of inorganic biochemistry, 2000, Volume: 79, Issue:1-4

    Topics: Aluminum; Alzheimer Disease; Anti-Ulcer Agents; Bismuth; Calcium; Chemistry, Bioinorganic; Common Cold; Dentifrices; Fluorine; Humans; Tin; Ulcer; Zinc

2000
[PET imaging of dementia].
    Nihon rinsho. Japanese journal of clinical medicine, 1985, Volume: 43, Issue:7

    Topics: Adolescent; Adult; Aged; Alzheimer Disease; Brain; Carbon Radioisotopes; Child; Dementia; Fluorine; Humans; Huntington Disease; Middle Aged; Oxygen Radioisotopes; Radioisotopes; Tomography, Emission-Computed

1985

Other Studies

19 other study(ies) available for fluorine and Alzheimer Disease

ArticleYear
Multi-fluorine labeled indanone derivatives as potential MRI imaging probes for β-Amyloid plaques.
    Chemical biology & drug design, 2023, Volume: 101, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Fluorine; Humans; Indans; Magnetic Resonance Imaging; Mice; Mice, Transgenic; Plaque, Amyloid; Tissue Distribution

2023
New Benzodihydrofuran Derivatives Alter the Amyloid β Peptide Aggregation: Strategies To Develop New Anti-Alzheimer Drugs.
    ACS chemical neuroscience, 2023, 08-02, Volume: 14, Issue:15

    Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Chalcone; Chalcones; Fluorine; Humans

2023
Fluorine-19 magnetic resonance imaging probe for the detection of tau pathology in female rTg4510 mice.
    Journal of neuroscience research, 2018, Volume: 96, Issue:5

    Topics: Aged; Alzheimer Disease; Animals; Benzoxazoles; Brain; Butadienes; Disease Models, Animal; Female; Fluorine; Fluorine-19 Magnetic Resonance Imaging; Humans; Male; Mice; Mice, Transgenic; Neurofibrillary Tangles; tau Proteins; Tauopathies

2018
β-Secretase (BACE1) inhibitors with high in vivo efficacy suitable for clinical evaluation in Alzheimer's disease.
    Journal of medicinal chemistry, 2013, May-23, Volume: 56, Issue:10

    Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Brain Chemistry; Enzyme Inhibitors; Female; Fluorine; Humans; Indicators and Reagents; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Molecular; Oxazines; Rats; Rats, Wistar; Structure-Activity Relationship; X-Ray Diffraction

2013
Polyfluorinated bis-styrylbenzenes as amyloid-β plaque binding ligands.
    Bioorganic & medicinal chemistry, 2014, Apr-15, Volume: 22, Issue:8

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzene; Binding, Competitive; Brain; Contrast Media; Drug Design; Fluorescent Dyes; Fluorine; Humans; Ligands; Magnetic Resonance Spectroscopy; Mice; Mice, Transgenic; Protein Binding; Spectrometry, Fluorescence

2014
(18)F-labeling syntheses and preclinical evaluation of functionalized nanoliposomes for Alzheimer's disease.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2016, Jun-10, Volume: 88

    Topics: Alzheimer Disease; Animals; Autoradiography; Brain; Female; Fluorine; Fluorine Radioisotopes; Genes, Transgenic, Suicide; Liposomes; Male; Mice; Molecular Structure; Nanostructures; Positron-Emission Tomography; Radiopharmaceuticals; Technology, Pharmaceutical; Tissue Distribution

2016
The effects of fluorine substitution on the chemical properties and inhibitory capacity of Donepezil anti-Alzheimer drug; density functional theory and molecular docking calculations.
    Journal of molecular graphics & modelling, 2017, Volume: 71

    Topics: Alzheimer Disease; Donepezil; Electrons; Fluorine; Humans; Hydrogen Bonding; Indans; Models, Molecular; Molecular Docking Simulation; Piperidines; Quantum Theory; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Static Electricity

2017
Synthesis of organophosphates with fluorine-containing leaving groups as serine esterase inhibitors with potential for Alzheimer disease therapeutics.
    Bioorganic & medicinal chemistry letters, 2009, Oct-01, Volume: 19, Issue:19

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Fluorine; Horses; Humans; Neuroprotective Agents; Organophosphates; Swine

2009
Effect of chirality of small molecule organofluorine inhibitors of amyloid self-assembly on inhibitor potency.
    Bioorganic & medicinal chemistry letters, 2009, Dec-15, Volume: 19, Issue:24

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Fluorine; Humans; Microscopy, Atomic Force; Propionates; Spectrometry, Fluorescence; Stereoisomerism

2009
BACE-1 inhibitors part 3: identification of hydroxy ethylamines (HEAs) with nanomolar potency in cells.
    Bioorganic & medicinal chemistry letters, 2008, Feb-01, Volume: 18, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Asparagine; Aspartic Acid Endopeptidases; Combinatorial Chemistry Techniques; Crystallography, X-Ray; Disease Models, Animal; Ethylamines; Fluorine; Mice; Molecular Structure; Nanotechnology; Structure-Activity Relationship

2008
NIH Conference. Brain imaging: aging and dementia.
    Annals of internal medicine, 1984, Volume: 101, Issue:3

    Topics: Adult; Aged; Aging; Alzheimer Disease; Brain; Deoxyglucose; Down Syndrome; Female; Fluorine; Fluorodeoxyglucose F18; Glucose; Humans; Male; Mental Processes; Middle Aged; Radioisotopes; Tomography, Emission-Computed; Tomography, X-Ray Computed; Wechsler Scales

1984
Cerebral metabolic relationships for selected brain regions in Alzheimer's, Huntington's, and Parkinson's diseases.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1984, Volume: 4, Issue:4

    Topics: Aged; Alzheimer Disease; Cerebral Cortex; Deoxyglucose; Fluorine; Humans; Huntington Disease; Middle Aged; Parkinson Disease; Radioisotopes

1984
The diagnosis of Alzheimer-type dementia. A preliminary comparison of positron emission tomography and proton magnetic resonance.
    JAMA, 1984, Nov-16, Volume: 252, Issue:19

    Topics: Alzheimer Disease; Deoxyglucose; Fluorine; Fluorodeoxyglucose F18; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Radioisotopes; Tomography, Emission-Computed; Tomography, X-Ray Computed

1984
Regional cerebral metabolic alterations in dementia of the Alzheimer type: positron emission tomography with [18F]fluorodeoxyglucose.
    Journal of computer assisted tomography, 1983, Volume: 7, Issue:4

    Topics: Aged; Alzheimer Disease; Cerebral Cortex; Dementia; Deoxy Sugars; Deoxyglucose; Female; Fluorine; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Radioisotopes; Tomography, Emission-Computed

1983
The fluorodeoxyglucose 18F scan in Alzheimer's disease and multi-infarct dementia.
    Archives of neurology, 1983, Volume: 40, Issue:12

    Topics: Aged; Alzheimer Disease; Brain; Dementia; Deoxy Sugars; Deoxyglucose; Female; Fluorine; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Radiography; Radioisotopes; Tomography, Emission-Computed

1983
A suggested mechanism for aluminum biotoxicity.
    Journal of theoretical biology, 1994, Nov-21, Volume: 171, Issue:2

    Topics: Aluminum; Alzheimer Disease; Dose-Response Relationship, Drug; Fluorine; Humans; Ontario; Silicon Dioxide; Water; Water Supply

1994
Interference of AlF4- with nucleotide and DNA binding of rat histone H1 in vitro. Implications for the pathogenesis of Alzheimer's disease.
    Neuroscience letters, 1991, Nov-11, Volume: 132, Issue:2

    Topics: Aluminum; Aluminum Compounds; Alzheimer Disease; Animals; Binding Sites; DNA; Fluorides; Fluorine; Histones; Liver; Nucleotides; Rats

1991
Neuroimaging and dementia.
    Neurologic clinics, 1986, Volume: 4, Issue:2

    Topics: Alzheimer Disease; Atrophy; Brain; Brain Neoplasms; Cerebral Angiography; Dementia; Deoxyglucose; Fluorine; Humans; Huntington Disease; Hydrocephalus; Magnetic Resonance Spectroscopy; Pneumoencephalography; Radioisotopes; Tomography, Emission-Computed; Tomography, X-Ray Computed

1986
Differences in lateral hemispheric asymmetries of glucose utilization between early- and late-onset Alzheimer-type dementia.
    The American journal of psychiatry, 1985, Volume: 142, Issue:5

    Topics: Age Factors; Aged; Alzheimer Disease; Brain; Deoxyglucose; Dominance, Cerebral; Female; Fluorine; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Radioisotopes; Tomography, Emission-Computed; Wechsler Scales

1985