Page last updated: 2024-08-23

fluorides and Osteosarcoma

fluorides has been researched along with Osteosarcoma in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19904 (10.00)18.7374
1990's17 (42.50)18.2507
2000's7 (17.50)29.6817
2010's11 (27.50)24.3611
2020's1 (2.50)2.80

Authors

AuthorsStudies
Burgard, SL; Couper, D; Douglass, CW; Hayes, C; Kim, FM1
Darko, GM; Gao, Y; Jiang, Y; Sun, D; Wang, H; Yang, Y1
Nakamoto, T; Rawls, HR1
Deng, S; Guo, F; Jin, X; Li, M; Wu, G; Wu, L1
Ametamey, SM; Arlt, MJ; Born, W; Brennecke, P; Campanile, C; Fischer, CR; Fuchs, B; Gvozdenovic, A; Honer, M; Krämer, SD; Müller, A; Sabile, AA; Schibli, R1
Blakey, K; Craft, AW; Feltbower, RG; Gómez Pozo, B; James, PW; McKinney, PA; McNally, RJ; Murphy, MF; Norman, P; Parslow, RC; Stiller, C; Vincent, TJ1
Archer, NP; Napier, TS; Villanacci, JF1
Bafana, A; Gandhi, D; Kannan, K; Naoghare, PK; Sivanesan, S1
Kharb, S; Kundu, ZS; Lal, H; Sandhu, R1
Douglass, CW; Hayes, C; Hoover, RN; Joshipura, KJ; Kim, FM; Whitford, GM; Williams, PL1
Leclerc, BS; Levy, M1
DAHLIN, DC; HOLTZMAN, RB; LUCAS, HF2
DE DEUXCHAISNES, CN; KRANE, SM1
Bassin, EB; Davis, RB; Mittleman, MA; Wypij, D1
Douglass, CW; Joshipura, K1
Douglass, CW; Fears, TR; Hoover, RN; Medina, N; Whitford, GM1
Chou, MY; Ding, SJ; He, H; Huang, TH; Kao, CT1
Dubrow, R; Fitzgerald, EF; Gelberg, KH; Hwang, SA1
Bonjour, JP; Burgener, D; Caverzasio, J1
Kleerekoper, M1
Farley, JR; Hall, SL; Herring, S; Tanner, MA1
Baylink, DJ; Chevalley, T; Lau, KH; Takada, J1
Baylink, DJ; Hashimoto, H; Lau, KH; Thomas, AB1
Baylink, DJ; Lau, KH; Takada, J1
Ando, M; Hirano, S1
Schmid, C; Veldman, CM1
Desai, BS; Murthy, PB; Natarajan, M; Pillai, KS; Ramesh, N; Vuayaraghavan, AS1
Hashimoto, H; Lau, KH1
Arias, M; Baylink, DJ; Goodwin, C; Lau, KH; Mohan, S1
Colquhoun, J1
Grandjean, P; Jensen, OM; Juel, K; Olsen, JH1
Bonjour, JP; Caverzasio, J; Selz, T1
Farley, JR; Hall, SL; Herring, S; Matsuyama, T; Tarbaux, NM; Wergedal, JE1
Kawase, T; Orikasa, M; Suzuki, A1
Gabler, WL1
Lau, KH; Wang, SP; Yoo, A1
Wei, SH1
Gutierrez, GE; Katz, MS; Mundy, GR1

Reviews

3 review(s) available for fluorides and Osteosarcoma

ArticleYear
Fluoride Exposure in Early Life as the Possible Root Cause of Disease In Later Life.
    The Journal of clinical pediatric dentistry, 2018, Volume: 42, Issue:5

    Topics: Autistic Disorder; Bone Neoplasms; Brain; Calcinosis; Cariostatic Agents; Fluoridation; Fluorides; Humans; Intelligence Tests; Osteosarcoma; Pineal Gland; Thyroid Hormones

2018
PAGET'S DISEASE OF BONE: CLINICAL AND METABOLIC OBSERVATIONS.
    Medicine, 1964, Volume: 43

    Topics: Alkaline Phosphatase; Aspirin; Blood; Bone and Bones; Calcium; Citrates; Fluorides; Geriatrics; Heart Failure; Homeostasis; Humans; Hydroxyproline; Immobilization; Metabolism; Osteitis Deformans; Osteosarcoma; Phenylbutazone; Phosphates; Radioisotopes; Radionuclide Imaging; Sarcoma; Statistics as Topic; Urinary Calculi; Urine

1964
Non-dental tissue effects of fluoride.
    Advances in dental research, 1994, Volume: 8, Issue:1

    Topics: Arteriosclerosis; Bone and Bones; Bone Neoplasms; Female; Fluoridation; Fluorides; Humans; Male; Osteoporosis; Osteosarcoma; Prevalence

1994

Other Studies

37 other study(ies) available for fluorides and Osteosarcoma

ArticleYear
A case-control study of topical and supplemental fluoride use and osteosarcoma risk.
    Journal of the American Dental Association (1939), 2021, Volume: 152, Issue:5

    Topics: Bone Neoplasms; Cariostatic Agents; Case-Control Studies; Dental Caries; Fluorides; Fluorides, Topical; Humans; Osteosarcoma

2021
Identification of miR-200c-3p as a major regulator of SaoS2 cells activation induced by fluoride.
    Chemosphere, 2018, Volume: 199

    Topics: Bone Morphogenetic Protein 4; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Fluorides; Humans; MicroRNAs; Osteoblasts; Osteosarcoma; Sodium Fluoride; Transcription Factors

2018
Integrative analyses of key genes and regulatory elements in fluoride-affected osteosarcoma.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:9

    Topics: Adolescent; Bone Neoplasms; Computational Biology; Databases, Genetic; Fluorides; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; MicroRNAs; Neoplasm Recurrence, Local; Oligonucleotide Array Sequence Analysis; Osteosarcoma; Protein Interaction Maps; Survival Analysis; Transcription Factors

2019
Characterization of different osteosarcoma phenotypes by PET imaging in preclinical animal models.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2013, Volume: 54, Issue:8

    Topics: Animals; Bone Neoplasms; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Fluorides; Fluorodeoxyglucose F18; Humans; Mice; Misonidazole; Osteoblasts; Osteoclasts; Osteosarcoma; Phenotype; Positron-Emission Tomography; Tibia

2013
Is fluoride a risk factor for bone cancer? Small area analysis of osteosarcoma and Ewing sarcoma diagnosed among 0-49-year-olds in Great Britain, 1980-2005.
    International journal of epidemiology, 2014, Volume: 43, Issue:1

    Topics: Adolescent; Adult; Age Factors; Bone Neoplasms; Child; Child, Preschool; Drinking Water; Female; Fluoridation; Fluorides; Humans; Infant; Infant, Newborn; Male; Middle Aged; Osteosarcoma; Population Surveillance; Risk Factors; Sarcoma, Ewing; Sex Factors; Small-Area Analysis; United Kingdom; Young Adult

2014
Fluoride exposure in public drinking water and childhood and adolescent osteosarcoma in Texas.
    Cancer causes & control : CCC, 2016, Volume: 27, Issue:7

    Topics: Adolescent; Adult; Bone Neoplasms; Case-Control Studies; Child; Child, Preschool; Demography; Drinking Water; Female; Fluoridation; Fluorides; Humans; Infant; Infant, Newborn; Logistic Models; Male; Osteosarcoma; Risk Factors; Texas; Young Adult

2016
Fluoride-Induced Oxidative and Inflammatory Stress in Osteosarcoma Cells: Does It Affect Bone Development Pathway?
    Biological trace element research, 2017, Volume: 175, Issue:1

    Topics: Bone Development; Cell Line, Tumor; Fluorides; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Osteosarcoma; Oxidative Stress; Sodium Fluoride

2017
Serum fluoride and sialic acid levels in osteosarcoma.
    Biological trace element research, 2011, Volume: 144, Issue:1-3

    Topics: Adult; Aged; Alkaline Phosphatase; Bone Neoplasms; Calcium; Child; Child, Preschool; Female; Fluorides; Humans; Male; N-Acetylneuraminic Acid; Osteosarcoma; Phosphorus; Young Adult

2011
An assessment of bone fluoride and osteosarcoma.
    Journal of dental research, 2011, Volume: 90, Issue:10

    Topics: Adolescent; Adult; Bone and Bones; Bone Neoplasms; Case-Control Studies; Child; Confidence Intervals; Female; Fluorides; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Osteosarcoma; Risk Factors; Statistics, Nonparametric; Surveys and Questionnaires; Young Adult

2011
Bone fluoride levels, osteosarcoma risk not linked, study finds.
    Journal of the American Dental Association (1939), 2011, Volume: 142, Issue:9

    Topics: Bone and Bones; Bone Neoplasms; Cariostatic Agents; Fluorides; Humans; Osteosarcoma; Risk Factors

2011
Fluoride in drinking water and osteosarcoma incidence rates in the continental United States among children and adolescents.
    Cancer epidemiology, 2012, Volume: 36, Issue:2

    Topics: Adolescent; Bone Neoplasms; Child; Child, Preschool; Drinking Water; Female; Fluoridation; Fluorides; Humans; Male; Osteosarcoma; United States

2012
THE CONCENTRATION OF RA-226, RA-228, PB-210, LEAD AND FLUORIDE IN HUMAN BONE FROM INDIVIDUALS WITH AN OSTEOGENIC SARCOMA. ANL-6769.
    ANL, 1963

    Topics: Bone and Bones; Bone Neoplasms; Fluorides; Humans; Lead; Metabolism; Neoplasms; Neoplasms, Radiation-Induced; Osteosarcoma; Phosphates; Radioisotopes; Radium; Sarcoma

1963
RADIUM-226, RADIUM-228, LEAD-210, AND FLUORINE IN PERSONS WITH OSTEOGENIC SARCOMA.
    Science (New York, N.Y.), 1964, Jun-26, Volume: 144, Issue:3626

    Topics: Bone and Bones; Bone Neoplasms; Chemistry Techniques, Analytical; Fluorides; Fluorine; Humans; Lead; Osteosarcoma; Radioisotopes; Radium; Sarcoma

1964
Age-specific fluoride exposure in drinking water and osteosarcoma (United States).
    Cancer causes & control : CCC, 2006, Volume: 17, Issue:4

    Topics: Adolescent; Age Factors; Bone Neoplasms; Case-Control Studies; Child; Female; Fluoridation; Fluorides; Humans; Male; Osteosarcoma; United States

2006
Caution needed in fluoride and osteosarcoma study.
    Cancer causes & control : CCC, 2006, Volume: 17, Issue:4

    Topics: Bone Neoplasms; Fluoridation; Fluorides; Humans; Osteosarcoma

2006
A reproducibility study for a fluoride assay in bone.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2006, Volume: 15, Issue:5

    Topics: Animals; Bone Neoplasms; Deer; Fluorides; Humans; Ilium; Jaw; Least-Squares Analysis; Osteosarcoma; Pilot Projects; Reproducibility of Results; Risk Factors

2006
Cytotoxicity of orthodontic wire corroded in fluoride solution in vitro.
    The Angle orthodontist, 2007, Volume: 77, Issue:2

    Topics: Cariostatic Agents; Cell Line, Tumor; Cell Survival; Corrosion; Cytotoxins; Fluorides; Humans; Nickel; Orthodontic Wires; Osteosarcoma; Saliva, Artificial; Stainless Steel; Titanium

2007
Fluoride exposure and childhood osteosarcoma: a case-control study.
    American journal of public health, 1995, Volume: 85, Issue:12

    Topics: Adolescent; Adult; Bone Neoplasms; Case-Control Studies; Child; Child, Preschool; Confidence Intervals; Environmental Exposure; Female; Fluorides; Humans; Infant; Male; New York; Odds Ratio; Osteosarcoma; Population Surveillance; Risk Factors

1995
Fluoride increases tyrosine kinase activity in osteoblast-like cells: regulatory role for the stimulation of cell proliferation and Pi transport across the plasma membrane.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1995, Volume: 10, Issue:1

    Topics: Animals; Biological Transport; Bone Neoplasms; Cell Division; Cell Membrane; Cytosol; Dose-Response Relationship, Drug; Fluorides; Genistein; Isoflavones; Osteoblasts; Osteosarcoma; Phosphates; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Sodium; Tumor Cells, Cultured; Vanadates

1995
Fluoride increases net 45Ca uptake by SaOS-2 cells: The effect is phosphate dependent.
    Calcified tissue international, 1993, Volume: 53, Issue:3

    Topics: Alkaline Phosphatase; Calcium; DNA; Dose-Response Relationship, Drug; Fluorides; Humans; Osteoblasts; Osteosarcoma; Phosphates; Thymidine; Tumor Cells, Cultured; Verapamil

1993
Dexamethasone enhances the osteogenic effects of fluoride in human TE85 osteosarcoma cells in vitro.
    Calcified tissue international, 1996, Volume: 58, Issue:5

    Topics: Alkaline Phosphatase; beta-Cyclodextrins; Calcitriol; Cell Division; Collagen; Cyclodextrins; Dexamethasone; Dose-Response Relationship, Drug; Drug Synergism; Fluorides; Glucocorticoids; Humans; Osteocalcin; Osteogenesis; Osteosarcoma; Thymidine; Tritium; Tumor Cells, Cultured

1996
Fluoride at mitogenic concentrations increases the steady state phosphotyrosyl phosphorylation level of cellular proteins in human bone cells.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:7

    Topics: Bone and Bones; Dose-Response Relationship, Drug; Drug Synergism; Epidermal Growth Factor; Fluorides; Humans; Immunoblotting; Kinetics; Molecular Weight; Osteosarcoma; Phosphoproteins; Phosphorylation; Phosphotyrosine; Tumor Cells, Cultured

1996
Pretreatment with low doses of norethindrone potentiates the osteogenic effects of fluoride on human osteosarcoma cells.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1995, Volume: 10, Issue:10

    Topics: Alkaline Phosphatase; Androgens; Bone Neoplasms; Calcitriol; Collagen; Dose-Response Relationship, Drug; Drug Synergism; Fluorides; Humans; Norethindrone; Osteocalcin; Osteogenesis; Osteosarcoma; Progestins; Thymidine; Tumor Cells, Cultured

1995
Fluoride mediates apoptosis in osteosarcoma UMR 106 and its cytotoxicity depends on the pH.
    Archives of toxicology, 1997, Volume: 72, Issue:1

    Topics: Animals; Apoptosis; Bone Neoplasms; Calcimycin; Cell Count; Cell Line; Cell Survival; Culture Media; DNA Fragmentation; Dose-Response Relationship, Drug; Fluorides; Hydrogen-Ion Concentration; Ionophores; Macrophages, Alveolar; Mice; Necrosis; Osteosarcoma; Rats; Tumor Cells, Cultured

1997
Differential effects of fluoride and insulin-like growth factor I on sodium-dependent alanine and phosphate transport in a human osteoblast-like cell line.
    Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 1998, Volume: 8, Issue:1

    Topics: Alanine; Biological Transport; Bone Neoplasms; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorides; Genistein; Humans; Insulin-Like Growth Factor I; Osteoblasts; Osteosarcoma; Phosphates; Protein-Tyrosine Kinases; Sodium; Tumor Cells, Cultured

1998
Low levels of p53 mutations in Indian patients with osteosarcoma and the correlation with fluoride levels in bone.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2001, Volume: 20, Issue:3

    Topics: Adolescent; Bone and Bones; Bone Neoplasms; Child; DNA Damage; DNA Mutational Analysis; DNA Primers; DNA, Neoplasm; Female; Fluorides; Genes, p53; Humans; India; Male; Osteosarcoma; Polymerase Chain Reaction

2001
Differential effects of bacterial toxins on mitogenic actions of sodium fluoride and those of aluminum fluoride in human TE85 osteosarcoma cells.
    Molecular and cellular biochemistry, 2001, Volume: 228, Issue:1-2

    Topics: Alkaline Phosphatase; Aluminum Compounds; Bone Neoplasms; Cell Division; Cholera Toxin; Fluorides; Humans; Mitogen-Activated Protein Kinases; Mitogens; Osteosarcoma; Pertussis Toxin; Phosphorylation; Signal Transduction; Sodium Fluoride; Thymidine; Tumor Cells, Cultured; Tyrosine; Virulence Factors, Bordetella

2001
Bone cell mitogenic action of fluoroaluminate and aluminum fluoride but not that of sodium fluoride involves upregulation of the insulin-like growth factor system.
    Bone, 2002, Volume: 30, Issue:5

    Topics: Aluminum; Aluminum Compounds; Bone Neoplasms; Cell Division; DNA; Fluorides; Fluorine; Gene Expression; Humans; Insulin-Like Growth Factor Binding Protein 4; Insulin-Like Growth Factor Binding Protein 5; Insulin-Like Growth Factor II; Mitogens; Osteosarcoma; RNA, Messenger; Sodium Fluoride; Tumor Cells, Cultured; Up-Regulation

2002
Fluoridation and fractures.
    The New Zealand medical journal, 1992, Oct-28, Volume: 105, Issue:944

    Topics: Adolescent; Aged; Child; Female; Fluoridation; Fluorides; Hip Fractures; Humans; Male; Osteosarcoma

1992
Cancer incidence and mortality in workers exposed to fluoride.
    Journal of the National Cancer Institute, 1992, Dec-16, Volume: 84, Issue:24

    Topics: Adult; Female; Fluorides; Humans; Incidence; Male; Middle Aged; Neoplasms; Occupational Diseases; Occupational Exposure; Osteosarcoma; Respiratory Tract Neoplasms; Time Factors; Urinary Bladder Neoplasms

1992
Fluoride selectively stimulates Na-dependent phosphate transport in osteoblast-like cells.
    The American journal of physiology, 1991, Volume: 260, Issue:6 Pt 1

    Topics: Alanine; Animals; Biological Transport; Calcium; Cell Division; Cell Line; Cyclic AMP; Cycloheximide; Egtazic Acid; Fluorides; Kinetics; Osteoblasts; Osteosarcoma; Phosphates; Rats; Sarcoma, Experimental; Sodium

1991
Skeletal alkaline phosphatase specific activity is an index of the osteoblastic phenotype in subpopulations of the human osteosarcoma cell line SaOS-2.
    Metabolism: clinical and experimental, 1991, Volume: 40, Issue:7

    Topics: Alkaline Phosphatase; Bone and Bones; Cyclic AMP; Fluorides; Histocytochemistry; Humans; Microbial Collagenase; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Phenotype; Protein Biosynthesis; Thymidine; Tumor Cells, Cultured

1991
Aluminofluoride- and epidermal growth factor-stimulated DNA synthesis in MOB 3-4-F2 cells.
    Pharmacology & toxicology, 1991, Volume: 69, Issue:5

    Topics: Aluminum; Aluminum Compounds; Animals; Arachidonic Acid; Cell Line; DNA; Epidermal Growth Factor; Fluorides; Indomethacin; Mice; Osteoblasts; Osteosarcoma; Protein Kinase C; Tumor Cells, Cultured

1991
National Toxicology program report on fluoride and cancer.
    The Journal of the Oregon Dental Association, 1991,Summer, Volume: 60, Issue:4

    Topics: Animals; Bone Neoplasms; Carcinoma, Squamous Cell; Fluorides; Humans; Mice; Mouth Neoplasms; Osteosarcoma; Rats; United States

1991
Aluminum stimulates the proliferation and differentiation of osteoblasts in vitro by a mechanism that is different from fluoride.
    Molecular and cellular biochemistry, 1991, Jul-10, Volume: 105, Issue:2

    Topics: Alkaline Phosphatase; Alum Compounds; Animals; Calcitriol; Cell Division; Cells, Cultured; Chick Embryo; Collagen; Culture Media; DNA; Fluorides; Humans; Osteoblasts; Osteocalcin; Osteosarcoma; Thymidine; Tumor Cells, Cultured

1991
Conference report: Special Symposium, Scientific Update on Fluoride and the Public Health.
    Journal of dental research, 1990, Volume: 69, Issue:6

    Topics: Animals; Carcinoma, Squamous Cell; Dental Caries; Fluoridation; Fluorides; Humans; Mice; Osteosarcoma; Rats; United States; United States Dept. of Health and Human Services

1990
Alterations in hormone-sensitive adenylate cyclase of cloned rat osteosarcoma cells during long-term culture.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1986, Volume: 1, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Bone Neoplasms; Calcitonin; Dinoprostone; Fluorides; Guanosine Triphosphate; Hormones; Isoproterenol; Osteosarcoma; Parathyroid Hormone; Rats; Tumor Cells, Cultured

1986