Page last updated: 2024-10-27

flunitrazepam and Pregnancy

flunitrazepam has been researched along with Pregnancy in 52 studies

Flunitrazepam: A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
flunitrazepam : A 1,4-benzodiazepinone that is nitrazepam substituted by a methyl group at position 1 and by a fluoro group at position 2'. It is a potent hypnotic, sedative, and amnestic drug used to treat chronic insomnia.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"A prospective single-blind study was conducted to compare flunitrazepam vs trazodone in the premedication of patients undergoing day-case surgery for termination of pregnancy, with particular regard to the degree of preoperative sedation, intraoperative analgesia and postoperative recovery."5.07[Trazodone versus flunitrazepam in premedication in day-care surgery]. ( Andriolli, A; Bonazzi, M; Laveneziana, D; Marsicano, M; Prampolini, F; Riva, A; Speranza, R, 1994)
" We here examined autoradiographic binding of [(3)H]muscimol to measure the total population of GABA(A) receptors and [(3)H]flunitrazepam to assess density of benzodiazepine sites in the medial prefrontal cortex, bed nucleus of the stria terminalis, amygdala, hippocampus, and periaqueductal gray of female rats sacrificed on day 7 postpartum, day 10 of pregnancy, or as diestrous virgins."3.77Autoradiographic analysis of GABAA receptor binding in the neural anxiety network of postpartum and non-postpartum laboratory rats. ( Lonstein, JS; Miller, SM, 2011)
"The sensitivity of prenatally protein-malnourished rats to the amnestic properties of the benzodiazepine (BZ) receptor agonist, chlordiazepoxide (CDP), was studied in the male offspring of rats provided with a protein-deficient diet (6% casein) for 5 weeks prior to mating and throughout pregnancy."3.70Chlordiazepoxide-induced spatial learning deficits: dose-dependent differences following prenatal malnutrition. ( Fiacco, TT; Galler, JR; Rosene, DL; Shultz, PL; Shumsky, JS; Tonkiss, J; Vincitore, M, 2000)
"Flunitrazepam is a new oral premedicant with prominent sedative and anxiolytic actions."2.65Flunitrazepam versus placebo premedication for minor surgery. ( Kangas, L; Kanto, J; Mansikka, M, 1979)
" On several counts, the combination of ketamine and flunitrazepam was proved to reduce the adverse reactions seen with ketamine alone."2.64Reduction of psychotomimetic side effects of Ketalar (ketamine) by Rohypnol (flunitrazepam). A randomized, double-blind trial. ( Freuchen, I; Kühl, JB; Mikkelsen, BO; Ostergaard, J, 1976)
"Knowledge of the pharmacokinetic properties of the benzodiazepines is playing an increasingly important role in their use during pregnancy, labour and lactation."2.36Use of benzodiazepines during pregnancy, labour and lactation, with particular reference to pharmacokinetic considerations. ( Kanto, JH, 1982)
"Carvone is a natural terpene which can be purified as R-(-) or S-(+) enantiomers."1.40Inhibitory effects of carvone isomers on the GABAA receptor in primary cultures of rat cortical neurons. ( Delgado-Marín, L; García, DA; Sánchez-Borzone, M, 2014)
"Thymol is a naturally occurring phenolic monoterpene known for its anti-microbial and anti-oxidant properties."1.33Allosteric positive interaction of thymol with the GABAA receptor in primary cultures of mouse cortical neurons. ( Bujons, J; García, DA; Suñol, C; Vale, C, 2006)
"Effects of hyperthermia-induced seizures (HS) on GABAA and benzodiazepine (BDZ) receptor binding in immature rat brain were evaluated using in vitro autoradiography."1.33Hyperthermia-induced seizures modify the GABAA and benzodiazepine receptor binding in immature rat brain. ( Feria, A; González-Ramírez, M; Orozco, S; Rocha, L; Salgado, H, 2005)
"Phenobarbital (PhB) was administered to pregnant mice during days 9-18 of gestation."1.28Effect of prenatal and neonatal chronic exposure to phenobarbital on central and peripheral benzodiazepine receptors. ( Fares, F; Gavish, M; Pick, CG; Weizman, A; Yanai, J, 1990)
"Phenobarbital (PB) was administered to pregnant mice during days 9-21 of gestation."1.27Effects of prenatal phenobarbital on benzodiazepine receptor development. ( Garrett, KM; Tabakoff, B, 1986)
"[3H]muscimol was used for the labeling of GABA receptors and [3H]flunitrazepam for benzodiazepine receptors."1.26Ontogeny of high-affinity GABA and benzodiazepine receptors in the rat cerebellum: an autoradiographic study. ( Kuhar, MJ; Palacios, JM, 1981)

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-199030 (57.69)18.7374
1990's11 (21.15)18.2507
2000's9 (17.31)29.6817
2010's2 (3.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sánchez-Borzone, M1
Delgado-Marín, L1
García, DA2
Miller, SM1
Lonstein, JS1
Andersen, DL1
Eckert, AL1
Tsai, VW1
Burke, CJ1
Tannenberg, AE1
Dodd, PR1
Iqbal, U1
Dringenberg, HC1
Brien, JF2
Reynolds, JN2
Lopes, DV1
Caruso, RR1
Castro, NG1
Costa, PR1
da Silva, AJ1
Noël, F1
Bujons, J1
Vale, C1
Suñol, C1
González-Ramírez, M1
Orozco, S1
Salgado, H1
Feria, A1
Rocha, L2
González Ramírez, M1
Orozco Suárez, S1
Salgado Ceballos, H1
Feria Velasco, A1
McClain, RM1
Hoar, RM1
Maltby, JR1
Hamilton, RC1
Phillips, R1
Hösli, E2
Möhler, H1
Richards, JG1
Hösli, L2
Kanto, JH1
Brooksbank, BW1
Atkinson, DJ1
Balázs, R1
Olive, G1
Rey, E1
Lippa, AS1
Beer, B1
Sano, MC1
Vogel, RA1
Meyerson, LR1
Palacios, JM2
Kuhar, MJ2
Shibagaki, M1
Seo, M1
Asano, T1
Kiyono, S1
Aaltonen, L1
Erkkola, R2
Kanto, J3
Bonnardot, JP1
Cordebar, R1
Regan, JW1
Roeske, WR1
Yamamura, HI1
Giorgi, O1
Lecca, D1
Cancedda, E1
Serra, GP1
Corda, MG1
Hendrickson, A1
March, D1
Richards, G1
Erickson, A1
Shaw, C1
Bonazzi, M2
Riva, A2
Marsicano, M1
Prampolini, F1
Speranza, R1
Andriolli, A1
Laveneziana, D2
Revel, MP1
Pons, JC1
Lelaidier, C1
Fournet, P1
Vial, M1
Musset, D1
Labrune, M1
Frydman, R1
McAuley, JW1
Kroboth, PD1
Stiff, DD1
Reynolds, IJ1
Morrow, AL2
Devaud, LL1
Purdy, RH2
Paul, SM1
Concas, A1
Follesa, P1
Barbaccia, ML1
Biggio, G1
Bailey, CD1
Tonkiss, J1
Shultz, PL1
Shumsky, JS1
Fiacco, TT1
Vincitore, M1
Rosene, DL1
Galler, JR1
Rumpel, E1
Behrends, JC1
Grobin, AC1
Freuchen, I1
Ostergaard, J1
Kühl, JB1
Mikkelsen, BO1
Chiefari, M1
Mastronardi, P1
Palmieri, AM1
Martí Viaño, JL1
Núñez-Cacho de Lis, A1
Llombart Rosa, MC1
Bellvert Ortiz, C1
Niehoff, DL1
Kangas, L2
Mansikka, M1
Vitorica, J1
Park, D1
de Blas, AL1
Fares, F1
Weizman, A1
Pick, CG1
Yanai, J1
Gavish, M2
Lan, NC1
Chen, JS1
Belelli, D1
Pritchett, DB1
Seeburg, PH1
Gee, KW1
Rothe, T1
Bigl, V1
Miller, LG1
Roy, RB1
Weill, CL1
Lopez, F1
Ruiz, G1
Hamon, M1
Vergé, D1
Soyannwo, OA1
Elegbe, EO1
Odugbesan, CO1
Marczynski, TJ1
Urbancic, M1
Vitali, C1
Avnimelech-Gigus, N1
Feldon, J1
Myslobodsky, M1
Fioretti, P1
Melis, GB1
Gambacciani, M1
Galbani, P1
Ronca-Testoni, S1
Garrett, KM1
Tabakoff, B1
Pitkänen, Y1
Amoia, M1
Azzollini, CV1
Ippedico, M1
Donadio, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intravenous Ketamine for Pain Control During First Trimester Surgical Abortion[NCT03751423]Phase 3123 participants (Anticipated)Interventional2019-06-10Suspended (stopped due to Study on-hold due to COVID-19 pandemic restrictions. Will resume when possible.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for flunitrazepam and Pregnancy

ArticleYear
Use of benzodiazepines during pregnancy, labour and lactation, with particular reference to pharmacokinetic considerations.
    Drugs, 1982, Volume: 23, Issue:5

    Topics: Anti-Anxiety Agents; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Female; Flunitrazepam; Hum

1982
[Benzodiazepines and pregnancy. Transplacental passage, labor and lactation].
    L'Encephale, 1983, Volume: 9, Issue:4 Suppl 2

    Topics: Anti-Anxiety Agents; Biotransformation; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Female;

1983
Neuroactive steroid modulators of the stress response.
    Annals of the New York Academy of Sciences, 1995, Dec-29, Volume: 771

    Topics: Adrenalectomy; Alcoholism; Animals; Bridged Bicyclo Compounds, Heterocyclic; Desoxycorticosterone; E

1995

Trials

6 trials available for flunitrazepam and Pregnancy

ArticleYear
Comparison of flunitrazepam and thiopentone for induction of general anaesthesia.
    Canadian Anaesthetists' Society journal, 1980, Volume: 27, Issue:4

    Topics: Abortion, Therapeutic; Adult; Anesthesia, Inhalation; Anti-Anxiety Agents; Female; Flunitrazepam; Hu

1980
[Trazodone versus flunitrazepam in premedication in day-care surgery].
    Minerva anestesiologica, 1994, Volume: 60, Issue:3

    Topics: Abortion, Induced; Adolescent; Adult; Ambulatory Surgical Procedures; Analgesia; Anesthesia Recovery

1994
Reduction of psychotomimetic side effects of Ketalar (ketamine) by Rohypnol (flunitrazepam). A randomized, double-blind trial.
    Acta anaesthesiologica Scandinavica, 1976, Volume: 20, Issue:2

    Topics: Abortion, Induced; Adolescent; Adult; Anesthesia, Intravenous; Anti-Anxiety Agents; Blood Pressure;

1976
[Comparison between flunitrazepam and thiopental in the induction of anesthesia in abdominal cesarean section].
    Revista espanola de anestesiologia y reanimacion, 1978, Volume: 25, Issue:5

    Topics: Adult; Anesthesia, Obstetrical; Anti-Anxiety Agents; Apgar Score; Blood Circulation; Cesarean Sectio

1978
Flunitrazepam versus placebo premedication for minor surgery.
    Acta anaesthesiologica Scandinavica, 1979, Volume: 23, Issue:6

    Topics: Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Dilatation and Curettage; Double-Blind Method;

1979
[Clotiazepam vs flunitrazepam in premedication in a day hospital regimen].
    Minerva anestesiologica, 1987, Volume: 53, Issue:12

    Topics: Abortion, Induced; Adult; Ambulatory Surgical Procedures; Azepines; Drug Evaluation; Female; Flunitr

1987

Other Studies

43 other studies available for flunitrazepam and Pregnancy

ArticleYear
Inhibitory effects of carvone isomers on the GABAA receptor in primary cultures of rat cortical neurons.
    Chirality, 2014, Volume: 26, Issue:8

    Topics: Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclohexane Monoterpenes; Dose-Response Re

2014
Autoradiographic analysis of GABAA receptor binding in the neural anxiety network of postpartum and non-postpartum laboratory rats.
    Brain research bulletin, 2011, Aug-10, Volume: 86, Issue:1-2

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Autoradiography; Brain; Female; Flunitrazepam; GABA-A Recepto

2011
GABA(A) receptor sites in the developing human foetus.
    Brain research. Developmental brain research, 2002, Dec-15, Volume: 139, Issue:2

    Topics: Adult; Aged; Binding Sites; Cell Differentiation; Cerebral Cortex; Diazepam; Female; Fetus; Flunitra

2002
Chronic prenatal ethanol exposure alters hippocampal GABA(A) receptors and impairs spatial learning in the guinea pig.
    Behavioural brain research, 2004, Apr-02, Volume: 150, Issue:1-2

    Topics: Animals; Body Weight; Brain; Central Nervous System Depressants; Ethanol; Female; Flunitrazepam; GAB

2004
Characterization of a new synthetic isoflavonoid with inverse agonist activity at the central benzodiazepine receptor.
    European journal of pharmacology, 2004, Jul-14, Volume: 495, Issue:2-3

    Topics: Analysis of Variance; Animals; Bicuculline; Binding, Competitive; Brain; Dose-Response Relationship,

2004
Allosteric positive interaction of thymol with the GABAA receptor in primary cultures of mouse cortical neurons.
    Neuropharmacology, 2006, Volume: 50, Issue:1

    Topics: Anesthetics, Intravenous; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Chloride Channel

2006
Hyperthermia-induced seizures modify the GABAA and benzodiazepine receptor binding in immature rat brain.
    Cellular and molecular neurobiology, 2005, Volume: 25, Issue:6

    Topics: Animals; Animals, Newborn; Autoradiography; Brain; Child; Female; Fever; Flunitrazepam; GABA Agonist

2005
Hyperthermia-induced seizures modify the GABA(A) and benzodiazepine receptor binding in immature rat brain.
    Cellular and molecular neurobiology, 2007, Volume: 27, Issue:2

    Topics: Age Factors; Animals; Autoradiography; Brain; Female; Fever; Flunitrazepam; GABA Agonists; GABA Modu

2007
The effect of flunitrazepam on reproduction in the rat. The use of cross-fostering in the evaluation of postnatal parameters in rat reproduction studies.
    Toxicology and applied pharmacology, 1980, Mar-30, Volume: 53, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Cesarean Section; Female; Fertility; Flunitrazepam; Growth; Maternal B

1980
Autoradiographic localization of binding sites for [3H]gamma-aminobutyrate, [3H]muscimol,(+)[3H]bicuculline methiodide and [3H] flunitrazepam in cultures of rat cerebellum and spinal cord.
    Neuroscience, 1980, Volume: 5, Issue:9

    Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Autoradiography; Bicuculline; Binding Sites; Cells,

1980
Biochemical development of the human brain. III. Benzodiazepine receptors, free gamma-aminobutyrate (GABA) and other amino acids.
    Journal of neuroscience research, 1982, Volume: 8, Issue:4

    Topics: Adult; Aged; Aging; Amino Acids; Aspartic Acid; Brain; Cerebellum; Female; Flunitrazepam; Frontal Lo

1982
Differential ontogeny of type 1 and type 2 benzodiazepine receptors.
    Life sciences, 1981, May-21, Volume: 28, Issue:21

    Topics: Animals; Brain; Female; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Pregnancy; Protein Binding

1981
Ontogeny of high-affinity GABA and benzodiazepine receptors in the rat cerebellum: an autoradiographic study.
    Brain research, 1981, Volume: 254, Issue:4

    Topics: Aging; Animals; Autoradiography; Cerebellum; Clonazepam; Female; Flunitrazepam; gamma-Aminobutyric A

1981
Environmental enrichment to alleviate maze performance deficits in rats with microcephaly induced by x-irradiation.
    Physiology & behavior, 1981, Volume: 27, Issue:5

    Topics: Animals; Brain; Discrimination Learning; Dose-Response Relationship, Radiation; Female; Flunitrazepa

1981
Benzodiazepine receptors in the human fetus.
    Biology of the neonate, 1983, Volume: 44, Issue:1

    Topics: Adult; Animals; Benzodiazepines; Binding Sites; Brain; Cerebral Cortex; Female; Fetus; Flunitrazepam

1983
Autoradiographic localization of binding sites for inhibitory amino acids and their antagonists in cultured rat CNS.
    Progress in brain research, 1983, Volume: 58

    Topics: Amino Acids; Animals; Animals, Newborn; Autoradiography; Bicuculline; Brain Stem; Cells, Cultured; C

1983
[A narcotic ketamine-flunitrazepam combination for cesarean section].
    Cahiers d'anesthesiologie, 1984, Volume: 32, Issue:8 Suppl

    Topics: Adult; Anesthesia, Endotracheal; Apgar Score; Cesarean Section; Consciousness; Female; Flunitrazepam

1984
[Importance of the ketamine-flunitrazepam combination in elective abortion].
    Cahiers d'anesthesiologie, 1984, Volume: 32, Issue:8 Suppl

    Topics: Abortion, Induced; Adolescent; Adult; Aging; Anesthesia; Consciousness; Female; Flunitrazepam; Human

1984
The benzodiazepine receptor: its development and its modulation by gamma-aminobutyric acid.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 212, Issue:1

    Topics: Age Factors; Aminobutyrates; Animals; Benzodiazepines; Bicuculline; Brain Chemistry; Female; Fetus;

1980
Modulation of [35S]TBPS binding by ligands with preferential affinity for benzodiazepine BZ1 sites in the cerebral cortex of newborn and adult rats.
    European journal of pharmacology, 1995, Jun-23, Volume: 290, Issue:1

    Topics: Age Factors; Animals; Animals, Newborn; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Co

1995
Coincidental appearance of the alpha 1 subunit of the GABA-A receptor and the type I benzodiazepine receptor near birth in macaque monkey visual cortex.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1994, Volume: 12, Issue:4

    Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Antibodies, Monoclonal; Autoradiography; Binding, Co

1994
Magnetic resonance imaging of the fetus: a study of 20 cases performed without curarization.
    Prenatal diagnosis, 1993, Volume: 13, Issue:9

    Topics: Adipose Tissue; Agenesis of Corpus Callosum; Brain; Curare; Female; Fetal Diseases; Fetal Growth Ret

1993
Modulation of [3H]flunitrazepam binding by natural and synthetic progestational agents.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:1

    Topics: Animals; Cerebral Cortex; Female; Flunitrazepam; Male; Medroxyprogesterone; Pregnancy; Progesterone;

1993
Physiological modulation of GABA(A) receptor plasticity by progesterone metabolites.
    European journal of pharmacology, 1999, Jun-30, Volume: 375, Issue:1-3

    Topics: Animals; Binding Sites; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Convulsants

1999
Altered GABA(A)-benzodiazepine receptor number and pharmacology in the adult guinea pig cerebral cortex after chronic prenatal ethanol exposure.
    Alcoholism, clinical and experimental research, 1999, Volume: 23, Issue:11

    Topics: Animals; Central Nervous System Depressants; Cerebral Cortex; Ethanol; Female; Flunitrazepam; GABA M

1999
Chlordiazepoxide-induced spatial learning deficits: dose-dependent differences following prenatal malnutrition.
    Pharmacology, biochemistry, and behavior, 2000, Jan-01, Volume: 65, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Body Weight; Chlordiazepoxide; Chlorides; Dose-Response Relationship,

2000
Postsynaptic receptor occupancy during evoked transmission at striatal GABAergic synapses in vitro.
    Journal of neurophysiology, 2000, Volume: 84, Issue:2

    Topics: Animals; Cells, Cultured; Corpus Striatum; Electrophysiology; Female; Flunitrazepam; GABA Modulators

2000
3Alpha-hydroxy-5alpha-pregnan-20-one levels and GABA(A) receptor-mediated 36Cl(-) flux across development in rat cerebral cortex.
    Brain research. Developmental brain research, 2001, Nov-26, Volume: 131, Issue:1-2

    Topics: Allosteric Regulation; Animals; Animals, Newborn; Anti-Anxiety Agents; Biological Transport; Cerebra

2001
[Preliminary clinical considerations on the use of Roipnol in general anesthesia according to surgical specialty].
    Minerva anestesiologica, 1978, Volume: 44, Issue:4

    Topics: Anesthesia, General; Anesthesia, Obstetrical; Anti-Anxiety Agents; Cerebral Angiography; Cerebral Ve

1978
Ontogeny of GABA and benzodiazepine receptors: effects of Triton X-100, bromide and muscimol.
    Brain research, 1979, Dec-28, Volume: 179, Issue:2

    Topics: Age Factors; Animals; Anti-Anxiety Agents; Bromides; Cerebellum; Female; Flunitrazepam; gamma-Aminob

1979
The GABAA/benzodiazepine receptor complex in rat brain neuronal cultures. Characterization by immunoprecipitation.
    Brain research, 1990, Dec-24, Volume: 537, Issue:1-2

    Topics: Affinity Labels; Animals; Animals, Newborn; Brain; Cattle; Cells, Cultured; Female; Flunitrazepam; I

1990
Effect of prenatal and neonatal chronic exposure to phenobarbital on central and peripheral benzodiazepine receptors.
    Brain research, 1990, Jan-01, Volume: 506, Issue:1

    Topics: Aging; Animals; Brain; Female; Flunitrazepam; Male; Mice; Muscimol; Phenobarbital; Pregnancy; Prenat

1990
A steroid recognition site is functionally coupled to an expressed GABA(A)-benzodiazepine receptor.
    European journal of pharmacology, 1990, Jun-12, Volume: 188, Issue:6

    Topics: Cells, Cultured; Female; Flunitrazepam; Humans; Kidney; Pregnancy; Pregnanes; Receptors, GABA-A; Rec

1990
The ontogeny of benzodiazepine receptors in selected regions of the rat brain: effect of perinatal exposure to diazepam.
    Neuropharmacology, 1989, Volume: 28, Issue:5

    Topics: Animals; Brain; Brain Chemistry; Diazepam; Female; Flunitrazepam; Nerve Tissue Proteins; Pregnancy;

1989
Persistent alterations in GABAA receptor binding and function after prenatal lorazepam administration in the chick.
    Brain research bulletin, 1989, Volume: 23, Issue:3

    Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chick Embryo; Chickens;

1989
Chronic phenytoin treatment decreases GABAA but not beta-adrenoceptors in the cerebellum of young rats.
    European journal of pharmacology, 1989, Sep-13, Volume: 168, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Cerebellum; Female; Flunitrazepam; Kinetics;

1989
Effect of flunitrazepam (Rohypnol) on awareness during anaesthesia for caesarean section.
    African journal of medicine and medical sciences, 1988, Volume: 17, Issue:1

    Topics: Adult; Anesthesia, Inhalation; Anesthesia, Obstetrical; Awareness; Cesarean Section; Cognition; Fema

1988
Animal models of chronic anxiety and "fearlessness".
    Brain research bulletin, 1988, Volume: 21, Issue:3

    Topics: Animals; Anxiety; Brain; Cats; Diazepam; Disease Models, Animal; Fear; Female; Flumazenil; Flunitraz

1988
Prenatal chlordiazepoxide effects on metrazol seizures and benzodiazepine receptors density in adult albino rats.
    Life sciences, 1985, May-06, Volume: 36, Issue:18

    Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Chlordiazepoxide; Drug Resistance; Female; Flunitrazepa

1985
Evidence of specific benzodiazepine binding to myometrial membrane preparations from human pregnant uterus.
    Acta obstetricia et gynecologica Scandinavica, 1986, Volume: 65, Issue:4

    Topics: Adult; Benzodiazepines; Benzodiazepinones; Cell Membrane; Chlordiazepoxide; Diazepam; Female; Flunit

1986
Effects of prenatal phenobarbital on benzodiazepine receptor development.
    Journal of neurochemistry, 1986, Volume: 47, Issue:4

    Topics: Animals; Brain; Cerebellum; Diencephalon; Female; Flunitrazepam; gamma-Aminobutyric Acid; Male; Mice

1986
Placental transfer of flunitrazepam following intramuscular administration during labour.
    British journal of clinical pharmacology, 1987, Volume: 23, Issue:4

    Topics: Adult; Female; Flunitrazepam; Humans; Injections, Intramuscular; Labor, Obstetric; Maternal-Fetal Ex

1987
[Hyperkinetic effects of flunitrazepam and diazepam on the fetus].
    Minerva anestesiologica, 1987, Volume: 53, Issue:4

    Topics: Diazepam; Drug Interactions; Female; Fetal Movement; Flunitrazepam; Heart Rate; Humans; Hyperkinesis

1987