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flunitrazepam and Parkinson Disease

flunitrazepam has been researched along with Parkinson Disease in 5 studies

Flunitrazepam: A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
flunitrazepam : A 1,4-benzodiazepinone that is nitrazepam substituted by a methyl group at position 1 and by a fluoro group at position 2'. It is a potent hypnotic, sedative, and amnestic drug used to treat chronic insomnia.

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stasi, K1
Mitsacos, A1
Giompres, P1
Kouvelas, ED1
Triarhou, LC1
Araki, T1
Matsubara, M1
Fujihara, K1
Kato, H1
Imai, Y1
Itoyama, Y1
Lloyd, GK1
Lowenthal, A1
Javoy-Agid, F1
Constantidinis, J1
Griffiths, PD1
Sambrook, MA2
Perry, R1
Crossman, AR2
Robertson, RG1
Clarke, CA1
Boyce, S1

Other Studies

5 other studies available for flunitrazepam and Parkinson Disease

ArticleYear
Partial restoration of striatal GABAA receptor balance by functional mesencephalic dopaminergic grafts in mice with hereditary parkinsonism.
    Experimental neurology, 1999, Volume: 157, Issue:2

    Topics: Animals; Autoradiography; Brain Tissue Transplantation; Corpus Striatum; Fetal Tissue Transplantatio

1999
Gamma-aminobutyric acidA and benzodiazepine receptor alterations in the rat brain after unilateral 6-hydroxydopamine lesions of the medial forebrain bundle.
    Neurological research, 2002, Volume: 24, Issue:1

    Topics: Animals; Dopamine; Dopamine Uptake Inhibitors; Down-Regulation; Flunitrazepam; GABA Agonists; GABA M

2002
GABAA receptor complex function in frontal cortex membranes from control and neurological patients.
    European journal of pharmacology, 1991, May-02, Volume: 197, Issue:1

    Topics: Adult; Aged; Alzheimer Disease; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic;

1991
Changes in benzodiazepine and acetylcholine receptors in the globus pallidus in Parkinson's disease.
    Journal of the neurological sciences, 1990, Volume: 100, Issue:1-2

    Topics: Aged; Caudate Nucleus; Efferent Pathways; Flunitrazepam; Globus Pallidus; Humans; Parkinson Disease;

1990
The role of striatopallidal neurones utilizing gamma-aminobutyric acid in the pathophysiology of MPTP-induced parkinsonism in the primate: evidence from [3H]flunitrazepam autoradiography.
    Brain research, 1990, Oct-29, Volume: 531, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Brain; Carbidopa; Corpus Str

1990