flunitrazepam has been researched along with Liver Cirrhosis in 2 studies
Flunitrazepam: A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
flunitrazepam : A 1,4-benzodiazepinone that is nitrazepam substituted by a methyl group at position 1 and by a fluoro group at position 2'. It is a potent hypnotic, sedative, and amnestic drug used to treat chronic insomnia.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pharmacokinetic behaviour of flunitrazepam and its main active metabolite, N-desmethyl flunitrazepam, was investigated in 12 patients with liver disease (cirrhosis or hepatitis) compared to 6 healthy volunteers." | 1.28 | Pharmacokinetics of flunitrazepam following single dose oral administration in liver disease patients compared with healthy volunteers. ( Antoni, M; Cano, JP; Coassolo, P; Drouet-Coassolo, C; Iliadis, A, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahboucha, S | 1 |
| Pomier-Layrargues, G | 1 |
| Mamer, O | 1 |
| Butterworth, RF | 1 |
| Drouet-Coassolo, C | 1 |
| Iliadis, A | 1 |
| Coassolo, P | 1 |
| Antoni, M | 1 |
| Cano, JP | 1 |
2 other studies available for flunitrazepam and Liver Cirrhosis
| Article | Year |
|---|---|
Increased levels of pregnenolone and its neuroactive metabolite allopregnanolone in autopsied brain tissue from cirrhotic patients who died in hepatic coma.
Topics: Adult; Aged; Aged, 80 and over; Animals; Benzodiazepines; Brain Chemistry; Desoxycorticosterone; Fem | 2006 |
Pharmacokinetics of flunitrazepam following single dose oral administration in liver disease patients compared with healthy volunteers.
Topics: Administration, Oral; Adult; Chromatography, Gas; Flunitrazepam; Half-Life; Hepatitis, Viral, Human; | 1990 |