flunitrazepam has been researched along with Huntington Disease in 8 studies
Flunitrazepam: A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
flunitrazepam : A 1,4-benzodiazepinone that is nitrazepam substituted by a methyl group at position 1 and by a fluoro group at position 2'. It is a potent hypnotic, sedative, and amnestic drug used to treat chronic insomnia.
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (62.50) | 18.7374 |
1990's | 3 (37.50) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Reisine, TD | 2 |
Overstreet, D | 1 |
Gale, K | 1 |
Rossor, M | 1 |
Iversen, L | 1 |
Yamamura, HI | 3 |
Kish, SJ | 1 |
Shannak, KS | 1 |
Perry, TL | 1 |
Hornykiewicz, O | 1 |
Schoemaker, H | 1 |
Morelli, M | 1 |
Deshmukh, P | 1 |
Penney, JB | 1 |
Young, AB | 1 |
Nicholson, LF | 2 |
Faull, RL | 2 |
Waldvogel, HJ | 2 |
Dragunow, M | 1 |
Synek, BJ | 1 |
Wastek, GJ | 1 |
Speth, RC | 1 |
Bird, ED | 1 |
Lloyd, GK | 1 |
Lowenthal, A | 1 |
Javoy-Agid, F | 1 |
Constantidinis, J | 1 |
8 other studies available for flunitrazepam and Huntington Disease
Article | Year |
---|---|
Benzodiazepine receptors: the effect of GABA on their characteristics in human brain and their alteration in Huntington's disease.
Topics: Aged; Anti-Anxiety Agents; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Huntington Disease; Putam | 1980 |
Neuronal [3H]benzodiazepine binding and levels of GABA, glutamate, and taurine are normal in Huntington's disease cerebellum.
Topics: Amino Acids; Cerebellum; Flunitrazepam; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Haloperi | 1983 |
[3H]Ro5-4864 benzodiazepine binding in the kainate lesioned striatum and Huntington's diseased basal ganglia.
Topics: Aged; Animals; Benzodiazepinones; Binding Sites; Corpus Striatum; Flunitrazepam; Humans; Huntington | 1982 |
Quantitative autoradiography of neurotransmitter receptors in Huntington disease.
Topics: Adult; Autoradiography; Brain; Female; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Huntington Di | 1982 |
GABA and GABAA receptor changes in the substantia nigra of the rat following quinolinic acid lesions in the striatum closely resemble Huntington's disease.
Topics: Animals; Autoradiography; Disease Models, Animal; Flunitrazepam; Gene Expression; Huntington Disease | 1995 |
The distribution of GABAA-benzodiazepine receptors in the basal ganglia in Huntington's disease and in the quinolinic acid-lesioned rat.
Topics: Adult; Aged; Animals; Autoradiography; Basal Ganglia; Female; Flunitrazepam; Humans; Huntington Dise | 1993 |
Alterations in the benzodiazepine receptor of Huntington's diseased human brain.
Topics: Aged; Anti-Anxiety Agents; Brain; Cerebellum; Clonazepam; Diazepam; Flunitrazepam; Frontal Lobe; Hum | 1979 |
GABAA receptor complex function in frontal cortex membranes from control and neurological patients.
Topics: Adult; Aged; Alzheimer Disease; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; | 1991 |