flunitrazepam has been researched along with Glioma in 6 studies
Flunitrazepam: A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
flunitrazepam : A 1,4-benzodiazepinone that is nitrazepam substituted by a methyl group at position 1 and by a fluoro group at position 2'. It is a potent hypnotic, sedative, and amnestic drug used to treat chronic insomnia.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In vivo administration of 3H-labeled PK 11195 [1-(2-chlorophenyl-N-methyl-N-(1-methylpropyl)-3-isoquinoline carboxamide] or [3H]flunitrazepam with 5 mg of clonazepam per kg to rats with intracranial C6 gliomas resulted in high levels of tritiated-drug binding to the tumor as shown by quantitative autoradiography." | 3.67 | Imaging of a glioma using peripheral benzodiazepine receptor ligands. ( Ciliax, BJ; McKeever, P; Penney, JB; Starosta-Rubinstein, S; Young, AB, 1987) |
| "Binding of the isoquinoline PK 11195 and of the benzodiazepines Ro5-4864 and flunitrazepam was compared in glioma cells and tissues." | 3.67 | Isoquinoline and peripheral-type benzodiazepine binding in gliomas: implications for diagnostic imaging. ( Junck, L; Mancini, WR; Olson, JM; Penney, JB; Young, AB, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thomas, JW | 1 |
| Tallman, JF | 1 |
| Zhang, L | 1 |
| Tardy, M | 1 |
| Berry, JP | 1 |
| Escaig, F | 1 |
| Galle, P | 1 |
| Ikezaki, K | 2 |
| Black, KL | 2 |
| Santori, EM | 1 |
| Smith, ML | 1 |
| Becker, DP | 1 |
| Payne, BA | 1 |
| Toga, AW | 2 |
| Starosta-Rubinstein, S | 1 |
| Ciliax, BJ | 1 |
| Penney, JB | 2 |
| McKeever, P | 1 |
| Young, AB | 2 |
| Olson, JM | 1 |
| Junck, L | 1 |
| Mancini, WR | 1 |
6 other studies available for flunitrazepam and Glioma
| Article | Year |
|---|---|
Characterization of photoaffinity labeling of benzodiazepine binding sites.
Topics: Affinity Labels; Animals; Benzodiazepines; Brain; Cell Line; Cell Membrane; Cerebral Cortex; Corpus | 1981 |
[Localization of two neurotropic molecules in cultured glial cells by ion microscopy].
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Astrocytes; Flunitrazepam; Flurazepam; Glioma; M | 1992 |
Three-dimensional comparison of peripheral benzodiazepine binding and histological findings in rat brain tumor.
Topics: Animals; Brain Neoplasms; Female; Flunitrazepam; Glioma; Isoquinolines; Rats; Rats, Inbred Strains; | 1990 |
Imaging of brain tumors using peripheral benzodiazepine receptor ligands.
Topics: Animals; Autoradiography; Brain Neoplasms; Clonazepam; Female; Flunitrazepam; Glioma; Image Processi | 1989 |
Imaging of a glioma using peripheral benzodiazepine receptor ligands.
Topics: Adrenal Gland Neoplasms; Animals; Flunitrazepam; Glioma; Humans; Isoquinolines; Kidney; Mice; Mice, | 1987 |
Isoquinoline and peripheral-type benzodiazepine binding in gliomas: implications for diagnostic imaging.
Topics: Benzodiazepines; Benzodiazepinones; Brain Neoplasms; Cells, Cultured; Flunitrazepam; Glioma; Humans; | 1988 |