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flunitrazepam and Friedreich Ataxia

flunitrazepam has been researched along with Friedreich Ataxia in 1 studies

Flunitrazepam: A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
flunitrazepam : A 1,4-benzodiazepinone that is nitrazepam substituted by a methyl group at position 1 and by a fluoro group at position 2'. It is a potent hypnotic, sedative, and amnestic drug used to treat chronic insomnia.

Friedreich Ataxia: An autosomal recessive disease, usually of childhood onset, characterized pathologically by degeneration of the spinocerebellar tracts, posterior columns, and to a lesser extent the corticospinal tracts. Clinical manifestations include GAIT ATAXIA, pes cavus, speech impairment, lateral curvature of spine, rhythmic head tremor, kyphoscoliosis, congestive heart failure (secondary to a cardiomyopathy), and lower extremity weakness. Most forms of this condition are associated with a mutation in a gene on chromosome 9, at band q13, which codes for the mitochondrial protein frataxin. (From Adams et al., Principles of Neurology, 6th ed, p1081; N Engl J Med 1996 Oct 17;335(16):1169-75) The severity of Friedreich ataxia associated with expansion of GAA repeats in the first intron of the frataxin gene correlates with the number of trinucleotide repeats. (From Durr et al, N Engl J Med 1996 Oct 17;335(16):1169-75)

Research Excerpts

ExcerptRelevanceReference
"3H-Flunitrazepam binding was slightly lowered in the inferior olivary and dentate nuclei but was unchanged in the other FA brain regions examined."1.26Brain neurotransmitter receptors in Friedreich's ataxia. ( Azari, J; Barbeau, A; Huxtable, R; Johnson, PC; Reisine, TD; Yamamura, HI, 1979)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reisine, TD1
Azari, J1
Johnson, PC1
Barbeau, A1
Huxtable, R1
Yamamura, HI1

Other Studies

1 other study available for flunitrazepam and Friedreich Ataxia

ArticleYear
Brain neurotransmitter receptors in Friedreich's ataxia.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1979, Volume: 6, Issue:2

    Topics: Adult; Benzodiazepines; Brain; Cerebellar Nuclei; Cerebellum; Dihydroalprenolol; Flunitrazepam; Frie

1979