flunitrazepam has been researched along with Epilepsy, Tonic-Clonic in 2 studies
Flunitrazepam: A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
flunitrazepam : A 1,4-benzodiazepinone that is nitrazepam substituted by a methyl group at position 1 and by a fluoro group at position 2'. It is a potent hypnotic, sedative, and amnestic drug used to treat chronic insomnia.
Epilepsy, Tonic-Clonic: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Three cases of convulsive status epilepticus (CSE) following abrupt discontinuation of long-term use of 25 mg of lorazepam in one patient and more than 20 mg of flunitrazepam in two patients are presented; they were non-epileptics and free of other high-risk factors for seizures." | 3.70 | Convulsive status epilepticus following abrupt high-dose benzodiazepine discontinuation. ( Angelopoulos, EK; Chioni, A; Daskalopoulou, EG; Gatzonis, SD; Mantouvalos, V; Siafakas, A; Zournas, C, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ben-Cherif, W | 1 |
| Gharbi, R | 1 |
| Sebai, H | 1 |
| Dridi, D | 1 |
| Boughattas, NA | 1 |
| Ben-Attia, M | 1 |
| Gatzonis, SD | 1 |
| Angelopoulos, EK | 1 |
| Daskalopoulou, EG | 1 |
| Mantouvalos, V | 1 |
| Chioni, A | 1 |
| Zournas, C | 1 |
| Siafakas, A | 1 |
2 other studies available for flunitrazepam and Epilepsy, Tonic-Clonic
| Article | Year |
|---|---|
Neuropharmacological screening of two 1,5-benzodiazepine compounds in mice.
Topics: Animals; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Benzopyrans; Diazepam; Dose-Response R | 2010 |
Convulsive status epilepticus following abrupt high-dose benzodiazepine discontinuation.
Topics: Adult; Anti-Anxiety Agents; Dose-Response Relationship, Drug; Epilepsy, Tonic-Clonic; Female; Flunit | 2000 |