Page last updated: 2024-10-27

flunitrazepam and Coronary Disease

flunitrazepam has been researched along with Coronary Disease in 14 studies

Flunitrazepam: A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
flunitrazepam : A 1,4-benzodiazepinone that is nitrazepam substituted by a methyl group at position 1 and by a fluoro group at position 2'. It is a potent hypnotic, sedative, and amnestic drug used to treat chronic insomnia.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
"Although phenylephrine bolus administration is frequently used to increase coronary perfusion pressure in patients with coronary artery disease or valvular aortic stenosis, there are no data describing its effect on left ventricular function (LVF)."9.07Effect of phenylephrine bolus administration on global left ventricular function in patients with coronary artery disease and patients with valvular aortic stenosis. ( Beyer, M; Georgieff, M; Goertz, AW; Lindner, KH; Schirmer, U; Seefelder, C, 1993)
"Although phenylephrine bolus administration is frequently used to increase coronary perfusion pressure in patients with coronary artery disease or valvular aortic stenosis, there are no data describing its effect on left ventricular function (LVF)."5.07Effect of phenylephrine bolus administration on global left ventricular function in patients with coronary artery disease and patients with valvular aortic stenosis. ( Beyer, M; Georgieff, M; Goertz, AW; Lindner, KH; Schirmer, U; Seefelder, C, 1993)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199010 (71.43)18.7374
1990's3 (21.43)18.2507
2000's0 (0.00)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yara, M1
Tomino, M1
Miyata, K1
Ishida, Y1
Saiki, I1
Seta, N1
Hara, N1
Uchino, H1
Hennart, D2
d'Hollander, A2
Primo-Dubois, J2
Bastien, O1
Hercule, C1
George, M1
Girard, C1
Villard, J1
Nitenberg, A2
Marty, J2
Blanchet, F1
Zouioueche, S1
Baury, A1
Desmonts, JM2
Schulte-Sasse, U2
Hess, W3
Tarnow, J4
Goertz, AW1
Lindner, KH1
Seefelder, C1
Schirmer, U1
Beyer, M1
Georgieff, M1
Schaer, H1
Dewachter, B1
Massaut, J1
Schmidt, D1
Eberlein, HJ1
Colson, P1
Médioni, P1
Saussine, M1
Séguin, JR1
Cuchet, D1
Grolleau, D1
Chaptal, PA1
Roquefeuil, B1
Philip, I1
Foult, JM1
Joyon, D1
Lepage, JY1
Blanloeil, Y1
Pinaud, M1
Helias, J1
Auneau, C1
Cozian, A1
Souron, R1
Markschies-Hornung, A1

Trials

4 trials available for flunitrazepam and Coronary Disease

ArticleYear
[Hemodynamic analysis of 6 different anesthesia induction procedures in coronary surgery patients].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1982, Volume: 17, Issue:4

    Topics: Alfaxalone Alfadolone Mixture; Anesthesia, Intravenous; Coronary Artery Bypass; Coronary Disease; Di

1982
Effect of phenylephrine bolus administration on global left ventricular function in patients with coronary artery disease and patients with valvular aortic stenosis.
    Anesthesiology, 1993, Volume: 78, Issue:5

    Topics: Aged; Anesthesia, General; Aortic Valve Stenosis; Coronary Disease; Female; Flunitrazepam; Hemodynam

1993
Hemodynamic effect of calcium channel blockade during anesthesia for coronary artery surgery.
    Journal of cardiothoracic and vascular anesthesia, 1992, Volume: 6, Issue:4

    Topics: Anesthesia, Intravenous; Blood Pressure; Cardiac Output; Cardiopulmonary Bypass; Coronary Artery Byp

1992
Coronary and left ventricular hemodynamic responses following reversal of flunitrazepam-induced sedation with flumazenil in patients with coronary artery disease.
    Anesthesiology, 1991, Volume: 74, Issue:1

    Topics: Adult; Coronary Circulation; Coronary Disease; Diastole; Female; Flumazenil; Flunitrazepam; Humans;

1991

Other Studies

10 other studies available for flunitrazepam and Coronary Disease

ArticleYear
[Perioperative management of off-pump CABG for a 93-year-old man].
    Masui. The Japanese journal of anesthesiology, 2014, Volume: 63, Issue:10

    Topics: Aged, 80 and over; Anesthesia; Brain; Cerebrovascular Circulation; Consciousness Monitors; Coronary

2014
The haemodynamic effects of flunitrazepam in anaesthetized patients with valvular or coronary artery lesions.
    Acta anaesthesiologica Scandinavica, 1982, Volume: 26, Issue:3

    Topics: Adult; Anesthesia; Anti-Anxiety Agents; Blood Pressure; Cardiac Output; Coronary Disease; Electrocar

1982
[Anesthesia with flunitrazepam/fentanyl in the severe coronary patient. Hemodynamic study].
    Cahiers d'anesthesiologie, 1984, Volume: 32, Issue:8 Suppl

    Topics: Aged; Anesthesia; Coronary Artery Bypass; Coronary Disease; Female; Fentanyl; Flunitrazepam; Hemodyn

1984
Effects of flunitrazepam on left ventricular performance, coronary haemodynamics and myocardial metabolism in patients with coronary artery disease.
    British journal of anaesthesia, 1983, Volume: 55, Issue:12

    Topics: Carbon Dioxide; Coronary Circulation; Coronary Disease; Flunitrazepam; Heart Ventricles; Hemodynamic

1983
[The coronary patient, a challenge to the anesthesist].
    Der Anaesthesist, 1977, Volume: 26, Issue:5

    Topics: Adrenergic beta-Antagonists; Anesthesia, General; Angina Pectoris; Coronary Disease; Etomidate; Fent

1977
[Flunitrazepam-pretreatment for prevention of adverse cardiovascular effects following ketamine].
    Der Anaesthesist, 1979, Volume: 28, Issue:10

    Topics: Adult; Anesthesia, Local; Anti-Anxiety Agents; Cardiovascular System; Coronary Disease; Drug Evaluat

1979
Hemodynamic effects of flunitrazepam in the coronary patient under moderated analgesic anesthesia.
    Acta anaesthesiologica Belgica, 1979, Volume: 30 Suppl

    Topics: Anesthesia; Anti-Anxiety Agents; Coronary Disease; Dose-Response Relationship, Drug; Flunitrazepam;

1979
[Induction of anaesthesia in patients with coronary artery disease: flunitrazepam, diazepam, ketamine, fentanyl. A haemodynamic study (author's transl)].
    Der Anaesthesist, 1979, Volume: 28, Issue:1

    Topics: Adult; Aged; Anesthetics; Coronary Artery Bypass; Coronary Disease; Diazepam; Fentanyl; Flunitrazepa

1979
Hemodynamic effects of diazepam, flunitrazepam, and midazolam in patients with ischemic heart disease: assessment with a radionuclide approach.
    Anesthesiology, 1986, Volume: 65, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Coronary Disease; Coronary Vessels; Diazepam; Flunitrazepam; Hemodyn

1986
Isoflurane improves the tolerance to pacing-induced myocardial ischemia.
    Anesthesiology, 1986, Volume: 64, Issue:2

    Topics: Adult; Aged; Angina Pectoris; Cardiac Output; Cardiac Pacing, Artificial; Coronary Circulation; Coro

1986