flunitrazepam has been researched along with Complication, Postoperative in 15 studies
Flunitrazepam: A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
flunitrazepam : A 1,4-benzodiazepinone that is nitrazepam substituted by a methyl group at position 1 and by a fluoro group at position 2'. It is a potent hypnotic, sedative, and amnestic drug used to treat chronic insomnia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Report on a case of cardiac arrest and coma lasting 10 hours secondary to the i." | 5.26 | [Intraoperative cardiac arrest and postoperative coma secondary to flunitrazepam (Rohypnol) (author's transl)]. ( Janda, A; Wagner, G, 1980) |
| "The delirium-free protocol (DFP) group was given an intramuscular injection of diazepam at 20:00 h each night, as well as a continuous intravenous infusion of flunitrazepam and pethidine administered over 8 h, for the first three nights postoperatively." | 5.10 | A novel approach to the prevention of postoperative delirium in the elderly after gastrointestinal surgery. ( Aizawa, K; Kanai, T; Kawano, Y; Miyazawa, N; Saikawa, Y; Takabayashi, T; Yamamoto, T, 2002) |
| " Univariate analyses showed that older age, male gender, additional flunitrazepam for sedation in intensive care unit (ICU) after surgery, longer periods of time under mechanical ventilation after surgery, longer ICU stays, occurrence of postoperative complications, and longer hospital stays were significantly associated with postoperative delirium." | 3.78 | Incidence and risk factors of postoperative delirium in patients with esophageal cancer. ( Ando, N; Fujisawa, D; Hashiguchi, S; Kitagawa, Y; Mimura, M; Miyajima, K; Ozawa, S; Shirahase, J; Takeuchi, H; Takeuchi, M; Yoshimura, K, 2012) |
| "Flunitrazepam was not a very satisfactory drug for the induction of anaesthesia, and recovery was too prolonged for routine use." | 2.64 | Clinical studies of induction agents XLIII: Flunitrazepam. ( Clarke, RS; Dundee, JW; Gaston, JH; Varadarajan, CR, 1976) |
| "Report on a case of cardiac arrest and coma lasting 10 hours secondary to the i." | 1.26 | [Intraoperative cardiac arrest and postoperative coma secondary to flunitrazepam (Rohypnol) (author's transl)]. ( Janda, A; Wagner, G, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (66.67) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yara, M | 1 |
| Tomino, M | 1 |
| Miyata, K | 1 |
| Ishida, Y | 1 |
| Saiki, I | 1 |
| Seta, N | 1 |
| Hara, N | 1 |
| Uchino, H | 1 |
| Takeuchi, M | 1 |
| Takeuchi, H | 1 |
| Fujisawa, D | 1 |
| Miyajima, K | 1 |
| Yoshimura, K | 1 |
| Hashiguchi, S | 1 |
| Ozawa, S | 1 |
| Ando, N | 1 |
| Shirahase, J | 1 |
| Kitagawa, Y | 1 |
| Mimura, M | 1 |
| Janda, A | 1 |
| Wagner, G | 1 |
| Schmutzler, S | 1 |
| Uges, D | 1 |
| Agoston, S | 1 |
| Langrehr, D | 1 |
| De Ville, A | 1 |
| Dubois-Primo, J | 1 |
| Bouton, JM | 1 |
| Rosele, B | 1 |
| David, A | 1 |
| Krivosic-Horber, R | 1 |
| Meites, G | 1 |
| Portecazaux, A | 1 |
| Pessey, JJ | 1 |
| Gobeaux, D | 1 |
| Di Florio, T | 1 |
| Goucke, R | 1 |
| Spies, CD | 1 |
| Dubisz, N | 1 |
| Funk, W | 1 |
| Blum, S | 1 |
| Müller, C | 1 |
| Rommelspacher, H | 1 |
| Brummer, G | 1 |
| Specht, M | 1 |
| Hannemann, L | 1 |
| Striebel, HW | 1 |
| Aizawa, K | 1 |
| Kanai, T | 1 |
| Saikawa, Y | 1 |
| Takabayashi, T | 1 |
| Kawano, Y | 1 |
| Miyazawa, N | 1 |
| Yamamoto, T | 1 |
| Dundee, JW | 1 |
| Varadarajan, CR | 1 |
| Gaston, JH | 1 |
| Clarke, RS | 1 |
| Heermann, J | 1 |
| Candas, H | 1 |
| Schaer, H | 1 |
| Navarro Ariza, J | 1 |
| Montero Benzo, R | 1 |
| Barber Dolz, L | 1 |
| Vicente Sánchez, JL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Standardised Nurse-led Approach for Risk Screening and Decrease of Alcohol Withdrawal Among Adult Inpatients With Alcohol Dependence in an Ear, Nose, Throat and Jaw Surgery Department[NCT02782156] | 89 participants (Actual) | Observational | 2014-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for flunitrazepam and Complication, Postoperative
| Article | Year |
|---|---|
Prophylaxis of alcohol withdrawal syndrome in alcohol-dependent patients admitted to the intensive care unit after tumour resection.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Chlormethiazole; Clonidine; Critical Care | 1995 |
A novel approach to the prevention of postoperative delirium in the elderly after gastrointestinal surgery.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Anxiety Agents; Delirium; Diazepam; Digestive Syst | 2002 |
Clinical studies of induction agents XLIII: Flunitrazepam.
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Anti-Anxiety Agents; Chemical Phenomena; Chemistry | 1976 |
12 other studies available for flunitrazepam and Complication, Postoperative
| Article | Year |
|---|---|
[Perioperative management of off-pump CABG for a 93-year-old man].
Topics: Aged, 80 and over; Anesthesia; Brain; Cerebrovascular Circulation; Consciousness Monitors; Coronary | 2014 |
Incidence and risk factors of postoperative delirium in patients with esophageal cancer.
Topics: Adult; Aged; Aged, 80 and over; Anti-Anxiety Agents; Delirium; Esophageal Neoplasms; Esophagectomy; | 2012 |
[Intraoperative cardiac arrest and postoperative coma secondary to flunitrazepam (Rohypnol) (author's transl)].
Topics: Anti-Anxiety Agents; Bradycardia; Coma; Dose-Response Relationship, Drug; Female; Flunitrazepam; Hea | 1980 |
[Rohypnol poisoning as a cause of postanesthetic coma and the success of 4-aminopyridine therapy].
Topics: 4-Aminopyridine; Adult; Aminopyridines; Anesthesia; Coma; Female; Flunitrazepam; Humans; Naloxone; P | 1984 |
[Anesthesia and pediatric cardiac surgery in children weighing less than 10 kg].
Topics: Anesthesia, Inhalation; Body Weight; Cardiopulmonary Bypass; Child, Preschool; Flunitrazepam; Heart | 1984 |
[Flunitrazepam by the rectal route as premedication in children].
Topics: Adolescent; Amnesia; Behavior; Child; Child, Preschool; Consciousness; Female; Flunitrazepam; Heart | 1984 |
[Importance of flunitrazepam for the reduction of bleeding in rhinoplasty].
Topics: Adolescent; Adult; Female; Fentanyl; Flunitrazepam; Hemorrhage; Humans; Intraoperative Complications | 1984 |
[Importance of flunitrazepam as a complement to peridural anesthesia in aged subjects and in those presenting risk factors in orthopedic surgery].
Topics: Aged; Anesthesia, Epidural; Blood Pressure; Body Temperature; Bone and Bones; Electrocardiography; F | 1984 |
Reduction of dopamine release and postoperative emesis by benzodiazepines.
Topics: Animals; Dopamine; Flunitrazepam; Midazolam; Postoperative Complications; Rats; Vomiting | 1993 |
[Prolongated amnesia after "rohypnol" i.v. before local anesthesia and responsiveness during operation (author's transl)].
Topics: Amnesia; Anti-Anxiety Agents; Blood Pressure; Flunitrazepam; Heart Rate; Humans; Postoperative Compl | 1977 |
[The coronary patient, a challenge to the anesthesist].
Topics: Adrenergic beta-Antagonists; Anesthesia, General; Angina Pectoris; Coronary Disease; Etomidate; Fent | 1977 |
[Study of flunitrazepam in heart surgery with C.E.C. Metabolic and respiratory aspects].
Topics: Adolescent; Adult; Anesthesia, General; Anesthetics; Anti-Anxiety Agents; Cardiac Surgical Procedure | 1977 |