flunitrazepam has been researched along with Autistic Disorder in 3 studies
Flunitrazepam: A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
flunitrazepam : A 1,4-benzodiazepinone that is nitrazepam substituted by a methyl group at position 1 and by a fluoro group at position 2'. It is a potent hypnotic, sedative, and amnestic drug used to treat chronic insomnia.
Autistic Disorder: A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Data from these single concentration ligand binding studies indicate that the GABAergic receptor system (3[H]-flunitrazepam labeled benzodiazepine binding sites and 3[H]-muscimol labeled GABA(A) receptors) is significantly reduced in high binding regions, marking for the first time an abnormality in the GABA system in autism." | 3.71 | Density and distribution of hippocampal neurotransmitter receptors in autism: an autoradiographic study. ( Bauman, ML; Blatt, GJ; Booker, AB; Fitzgerald, CM; Guptill, JT; Kemper, TL, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oblak, A | 1 |
| Gibbs, TT | 2 |
| Blatt, GJ | 3 |
| Guptill, JT | 2 |
| Booker, AB | 2 |
| Kemper, TL | 2 |
| Bauman, ML | 2 |
| Fitzgerald, CM | 1 |
3 other studies available for flunitrazepam and Autistic Disorder
| Article | Year |
|---|---|
Decreased GABAA receptors and benzodiazepine binding sites in the anterior cingulate cortex in autism.
Topics: Adaptor Proteins, Signal Transducing; Adult; Autistic Disorder; Down-Regulation; Female; Flunitrazep | 2009 |
[3H]-flunitrazepam-labeled benzodiazepine binding sites in the hippocampal formation in autism: a multiple concentration autoradiographic study.
Topics: Adolescent; Adult; Autistic Disorder; Autoradiography; Benzodiazepines; Binding Sites; Cerebellum; F | 2007 |
Density and distribution of hippocampal neurotransmitter receptors in autism: an autoradiographic study.
Topics: Adolescent; Adult; Autistic Disorder; Autoradiography; Binding Sites; Cell Count; Culture Techniques | 2001 |