Page last updated: 2024-10-27

flunitrazepam and Amnesia

flunitrazepam has been researched along with Amnesia in 27 studies

Flunitrazepam: A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
flunitrazepam : A 1,4-benzodiazepinone that is nitrazepam substituted by a methyl group at position 1 and by a fluoro group at position 2'. It is a potent hypnotic, sedative, and amnestic drug used to treat chronic insomnia.

Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)

Research Excerpts

ExcerptRelevanceReference
" The results suggest that the extent of the benzodiazepines' amnesic effects--both negative (anterograde) and positive (retrograde)--depends on the dosage and type of substance."6.66Anterograde and retrograde amnesia after lormetazepam and flunitrazepam. ( Aufdembrinke, B; Fichte, K; Ott, H; Rohloff, A, 1988)
" The results suggest that the extent of the benzodiazepines' amnesic effects--both negative (anterograde) and positive (retrograde)--depends on the dosage and type of substance."2.66Anterograde and retrograde amnesia after lormetazepam and flunitrazepam. ( Aufdembrinke, B; Fichte, K; Ott, H; Rohloff, A, 1988)
"Flunitrazepam was used in general and local anesthesia."1.26Practical experiences with flunitrazepam in anesthesia. ( Dworacek, B; Penners, HC, 1979)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199022 (81.48)18.7374
1990's2 (7.41)18.2507
2000's1 (3.70)29.6817
2010's2 (7.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cappelli, A1
Anzini, M1
Castriconi, F1
Grisci, G1
Paolino, M1
Braile, C1
Valenti, S1
Giuliani, G1
Vomero, S1
Di Capua, A1
Betti, L1
Giannaccini, G1
Lucacchini, A1
Ghelardini, C1
Di Cesare Mannelli, L1
Frosini, M1
Ricci, L1
Giorgi, G1
Mascia, MP1
Biggio, G1
Galizio, M1
Mathews, M1
Mason, M1
Panoz-Brown, D1
Prichard, A1
Soto, P1
Kumar, V1
Khanna, VK1
Seth, PK1
Singh, PN1
Bhattacharya, SK1
Tolksdorf, W2
Berlin, J2
Bethke, U2
Nieder, G1
Vinsová, E1
Rosele, B1
David, A1
Krivosic-Horber, R1
Parraguette, J1
Garbarini, T1
Diulcin, N1
Sicre, B1
Renum, B1
Fitzal, S1
Groll-Knapp, E1
Länger, W1
Riegler, R1
Dundee, JW3
George, KA3
Vardarajan, CR1
Clarke, RS1
Nair, SK1
Korttila, K3
Linnoila, M1
De Castro, J1
Parmentier, P1
Heermann, J1
Candas, H1
Saarnivaara, L2
Tarkkanen, J2
Himberg, JJ2
Hytönen, M2
Heipertz, W1
Vontin, H1
Schorer, R1
Junger, H1
Schulte-Steinberg, O1
Striebel, JP1
Westphal, KT1
Lutz, H1
Dworacek, B1
Penners, HC1
Suzuki, N1
Nishibori, M2
Kubota, Y1
Rager, P1
Bénézech, M1
Ott, H1
Rohloff, A1
Aufdembrinke, B1
Fichte, K1
Gentil, V1
Gorenstein, C1
Bello, CN1
Kurka, P1
Van de Walle, J1
Lauwers, P1
Adriaensen, H1

Trials

6 trials available for flunitrazepam and Amnesia

ArticleYear
[Psychosomatic effects of intramuscular premedication wtih flunitrazepam, innovar and a placebo in combination with atropine (author's transl)].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1981, Volume: 16, Issue:1

    Topics: Adult; Amnesia; Anti-Anxiety Agents; Anxiety; Atropine; Droperidol; Drug Combinations; Drug Therapy,

1981
[Premedication with flunitrazepam, lormetazepam or pethidine-promethazine. Psychometric study of subjective conditions].
    Der Anaesthesist, 1983, Volume: 32, Issue:6

    Topics: Adult; Amnesia; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Depression; Emotions; Flunitrazepam;

1983
Amnesic action of and skills related to driving after intravenous flunitrazepam.
    Acta anaesthesiologica Scandinavica, 1976, Volume: 20, Issue:2

    Topics: Adult; Amnesia; Anti-Anxiety Agents; Automobile Driving; Clinical Trials as Topic; Female; Flicker F

1976
Relative amnesic actions of diazepam, flunitrazepam and lorazepam in man.
    British journal of clinical pharmacology, 1977, Volume: 4, Issue:1

    Topics: Amnesia; Anesthesia; Anti-Anxiety Agents; Diazepam; Female; Flunitrazepam; Humans; Lorazepam; Time F

1977
Comparison of diazepam and flunitrazepam for sedation during local anaesthesia for bronchoscopy.
    British journal of anaesthesia, 1978, Volume: 50, Issue:3

    Topics: Adult; Aged; Amnesia; Anesthesia, Local; Anti-Anxiety Agents; Bronchoscopy; Cardiovascular System; D

1978
Anterograde and retrograde amnesia after lormetazepam and flunitrazepam.
    Psychopharmacology series, 1988, Volume: 6

    Topics: Amnesia; Amnesia, Retrograde; Anti-Anxiety Agents; Benzodiazepines; Double-Blind Method; Emotions; F

1988

Other Studies

21 other studies available for flunitrazepam and Amnesia

ArticleYear
Design, Synthesis, and Biological Evaluation of Imidazo[1,5-a]quinoline as Highly Potent Ligands of Central Benzodiazepine Receptors.
    Journal of medicinal chemistry, 2016, Apr-14, Volume: 59, Issue:7

    Topics: Amnesia; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepines; Binding Sites; Brain; Catt

2016
Amnestic drugs in the odor span task: Effects of flunitrazepam, zolpidem and scopolamine.
    Neurobiology of learning and memory, 2017, Volume: 145

    Topics: Amnesia; Animals; Cholinergic Antagonists; Discrimination, Psychological; Dose-Response Relationship

2017
Brain neurotransmitter receptor binding and nootropic studies on Indian Hypericum perforatum Linn.
    Phytotherapy research : PTR, 2002, Volume: 16, Issue:3

    Topics: Amnesia; Animals; Avoidance Learning; Behavior, Animal; Binding, Competitive; Brain; Dose-Response R

2002
[Ataracticoanalgesia in gynecological operation. I. Evidencing amnestic effects of flunitrazepam (Rohypnol, Roche)].
    Sbornik lekarsky, 1982, Volume: 84, Issue:3

    Topics: Adolescent; Adult; Aged; Amnesia; Anti-Anxiety Agents; Child; Female; Flunitrazepam; Genitalia, Fema

1982
[Flunitrazepam by the rectal route as premedication in children].
    Cahiers d'anesthesiologie, 1984, Volume: 32, Issue:8 Suppl

    Topics: Adolescent; Amnesia; Behavior; Child; Child, Preschool; Consciousness; Female; Flunitrazepam; Heart

1984
[Comparison of the effects of flunitrazepam and diazepam used in premedication].
    Cahiers d'anesthesiologie, 1984, Volume: 32, Issue:8 Suppl

    Topics: Adult; Aged; Amnesia; Anesthesia; Anxiety; Diazepam; Drug Tolerance; Female; Flunitrazepam; Hemodyna

1984
Flunitrazepam misuse and abuse in South Africa.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1999, Volume: 89, Issue:11

    Topics: Amnesia; Anti-Anxiety Agents; Depression; Female; Flunitrazepam; Humans; Illicit Drugs; Rape; Sleep

1999
Proceedings: Anaesthesia and amnesia with flunitrazepam.
    British journal of anaesthesia, 1976, Volume: 48, Issue:3

    Topics: Amnesia; Anesthesia, General; Anti-Anxiety Agents; Diazepam; Flunitrazepam; Humans

1976
The amnesic action of diazepam, flunitrazepam and lorazepam in man.
    Acta anaesthesiologica Belgica, 1976, Volume: 27 suppl

    Topics: Amnesia; Anti-Anxiety Agents; Diazepam; Dose-Response Relationship, Drug; Female; Flunitrazepam; Hum

1976
[Choice of a potentiator of analgesics].
    Annales de l'anesthesiologie francaise, 1976, Volume: 17, Issue:10

    Topics: Amnesia; Analgesics, Opioid; Anesthesia; Anesthetics; Autonomic Nerve Block; Barbiturates; Diazepam;

1976
[Prolongated amnesia after "rohypnol" i.v. before local anesthesia and responsiveness during operation (author's transl)].
    Laryngologie, Rhinologie, Otologie, 1977, Volume: 56, Issue:3

    Topics: Amnesia; Anti-Anxiety Agents; Blood Pressure; Flunitrazepam; Heart Rate; Humans; Postoperative Compl

1977
[Amnesia after the benzodiazepines flunitrazepam and lorazepam].
    Klinische Anasthesiologie und Intensivtherapie, 1978, Issue:17

    Topics: Amnesia; Anti-Anxiety Agents; Flunitrazepam; Humans; Lorazepam; Time Factors

1978
[Administration and dosage of flunitrazepam in combination with regional anesthesia].
    Klinische Anasthesiologie und Intensivtherapie, 1978, Issue:17

    Topics: Amnesia; Analgesia; Anesthesia, Conduction; Anesthesia, Spinal; Anti-Anxiety Agents; Diazepam; Drug

1978
[The sedative and amnesic effects of flunitrazepam during regional anaesthesia (author's transl)].
    Praktische Anasthesie, Wiederbelebung und Intensivtherapie, 1979, Volume: 14, Issue:1

    Topics: Adult; Aged; Alcohol Drinking; Amnesia; Anesthesia, Conduction; Anti-Anxiety Agents; Female; Flunitr

1979
Effect of age on amnesia and sedation induced by flunitrazepam during local anaesthesia for bronchoscopy.
    British journal of anaesthesia, 1978, Volume: 50, Issue:12

    Topics: Adult; Aged; Aging; Amnesia; Anesthesia, Local; Anti-Anxiety Agents; Bronchoscopy; Flunitrazepam; Hu

1978
Practical experiences with flunitrazepam in anesthesia.
    Acta anaesthesiologica Belgica, 1979, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Aged; Amnesia; Anesthesia, Conduction; Anesthesia, General; Anesthesia, Intraveno

1979
Analysis of 526 cases of intravenous flunitrazepam sedation in dentistry.
    Anesthesia progress, 1990, Volume: 37, Issue:4

    Topics: Adult; Aged; Amnesia; Anesthesia, Dental; Anesthesia, Intravenous; Conscious Sedation; Female; Fluni

1990
[Memory gaps and hypercomplex automatisms after a single oral dose of benzodiazepines: clinical and medico-legal aspects].
    Annales medico-psychologiques, 1986, Volume: 144, Issue:1

    Topics: Adult; Amnesia; Anti-Anxiety Agents; Automatism; Bromazepam; Drug Synergism; Ethanol; Female; Flunit

1986
Reversal of flunitrazepam amnestic effects by aminophylline.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:5

    Topics: Aminophylline; Amnesia; Flunitrazepam; Humans

1988
[Clinical experiences with Ro 05-4200 in anaesthesia(author's transl)].
    Der Anaesthesist, 1974, Volume: 23, Issue:9

    Topics: Adolescent; Adult; Aged; Amnesia; Anesthetics; Anti-Anxiety Agents; Blood Pressure; Chemical Phenome

1974
Clinical experimentation with flunitrazepam (Ro 05-4200).
    Acta anaesthesiologica Belgica, 1974, Volume: 25, Issue:3

    Topics: Amnesia; Animals; Anti-Anxiety Agents; Blood Circulation; Cardiovascular System; Cats; Drug Synergis

1974