Page last updated: 2024-10-27

flunitrazepam and Aging

flunitrazepam has been researched along with Aging in 56 studies

Flunitrazepam: A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
flunitrazepam : A 1,4-benzodiazepinone that is nitrazepam substituted by a methyl group at position 1 and by a fluoro group at position 2'. It is a potent hypnotic, sedative, and amnestic drug used to treat chronic insomnia.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"The properties of gamma-aminobutyric acid recognition sites, benzodiazepine binding sites and the effect of exogeneous gamma-aminobutyric acid on benzodiazepine binding were determined in crude membrane fractions prepared from the brains of DBA/2 mice at ages before (8-9 and 17-18 days), during (22-23 and 28-29 days) and after (40-43 days) the age of high susceptibility to audiogenic seizures."7.66gamma-Aminobutyric acid and benzodiazepine binding sites in audiogenic seizure-susceptible mice. ( Horton, RW; Meldrum, BS; Prestwich, SA, 1982)
"gamma-Aminobutyric acid (GABA) has been implicated in the development of hypertension and in the regulation of blood pressure."3.67The GABA/benzodiazepine receptor complex in the nervous system of a hypertensive strain of rat. ( Head, RA; Tunnicliff, G; Welborn, KL, 1984)
"The properties of gamma-aminobutyric acid recognition sites, benzodiazepine binding sites and the effect of exogeneous gamma-aminobutyric acid on benzodiazepine binding were determined in crude membrane fractions prepared from the brains of DBA/2 mice at ages before (8-9 and 17-18 days), during (22-23 and 28-29 days) and after (40-43 days) the age of high susceptibility to audiogenic seizures."3.66gamma-Aminobutyric acid and benzodiazepine binding sites in audiogenic seizure-susceptible mice. ( Horton, RW; Meldrum, BS; Prestwich, SA, 1982)
"We investigated the effects of the long-term administration of Kamikihito (KKT) on the specific binding of [3H]muscimol and [3H]flunitrazepam in the brains of young and aged rats using in vitro quantitative autoradiography."1.29Effects of Kamikihito, a traditional Chinese medicine, on neurotransmitter receptor binding in the aged rat brain determined by in vitro autoradiography (2): changes in GABAA and benzodiazepine receptor binding. ( Hasegawa, T; Hayashi, T; Ishihara, S; Kameyama, T; Kaneyuki, T; Morimasa, T; Nabeshima, T; Shohmori, T; Yamada, K, 1994)
" In aged rats, the dose-response curve was shifted to the left, indicating an increase in the potency of GABA to inhibit [3H]t-butylbicycloorthobenzoate binding."1.29GABAA receptor binding in the aging rat inferior colliculus. ( Albin, RL; Caspary, DM; Milbrandt, JC; Turgeon, SM, 1996)
"3H-flunitrazepam binding was studied in membranes from different brain regions and from kidneys and adrenals of young (5-month old) and aged (22-month old) rats."1.28Age-related changes in central and peripheral benzodiazepine binding sites. ( Hadjiivanova, C; Petkov, VV; Zamdjieva, S, 1992)
"kainic acid."1.28Effect of kainic acid administration to prepubescent rats on cholinergic markers in selected brain regions of adult rats. ( Guzmán-Godínez, G; Schliebs, R, 1992)
"Phenobarbital (PhB) was administered to pregnant mice during days 9-18 of gestation."1.28Effect of prenatal and neonatal chronic exposure to phenobarbital on central and peripheral benzodiazepine receptors. ( Fares, F; Gavish, M; Pick, CG; Weizman, A; Yanai, J, 1990)
"Flunitrazepam was given as an induction agent i."1.26A pharmacokinetic and pharmacodynamic study of flunitrazepam. ( Kangas, L; Kanto, J; Pakkanen, A, 1982)
"[3H]muscimol was used for the labeling of GABA receptors and [3H]flunitrazepam for benzodiazepine receptors."1.26Ontogeny of high-affinity GABA and benzodiazepine receptors in the rat cerebellum: an autoradiographic study. ( Kuhar, MJ; Palacios, JM, 1981)

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199024 (42.86)18.7374
1990's29 (51.79)18.2507
2000's3 (5.36)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Friemel, A1
Ebert, B1
Hutson, PH1
Brust, P1
Nieber, K1
Deuther-Conrad, W1
Sieghart, W3
Mayer, A1
Kangas, L1
Kanto, J1
Pakkanen, A1
Brooksbank, BW1
Atkinson, DJ1
Balázs, R1
Tunnicliff, G1
Welborn, KL1
Head, RA1
Altstein, M1
Dudai, Y1
Vogel, Z1
Pedigo, NW1
Schoemaker, H1
Morelli, M1
McDougal, JN1
Malick, JB1
Burks, TF1
Yamamura, HI1
Palacios, JM1
Kuhar, MJ1
Horton, RW1
Prestwich, SA1
Meldrum, BS1
Kubanis, P1
Zornetzer, SF1
Freund, G2
Lippa, AS1
Meyerson, LR1
Beer, B1
Chisholm, J1
Kellogg, C1
Lippa, A1
Gregor, P1
Sellinger, OZ1
Abbracchio, MP1
Balduini, W1
Coen, E1
Lombardelli, G1
Peruzzi, G1
Cattabeni, F1
Pech, C1
Boussaton, E1
Rigaud, J1
Carcarrère, F1
Lareng, L1
Cordebar, R1
Yamada, K2
Hayashi, T2
Hasegawa, T2
Ishihara, S2
Kameyama, T2
Morimasa, T2
Kaneyuki, T2
Shohmori, T2
Nabeshima, T2
Giorgi, O2
Cancedda, E1
Lecca, D1
Orlandi, M2
Corda, MG2
March, D2
Shaw, CA1
Ruano, D3
Machado, A2
Vitorica, J4
Pilachowski, J1
Guilarte, TR1
Taira, T1
Uusi-Oukari, M1
Korpi, ER1
Milbrandt, JC1
Albin, RL1
Turgeon, SM1
Caspary, DM1
Araujo, F1
Bentareha, R1
Ono, T1
Fueta, Y1
Janjua, NA1
Ohmori, O1
Ohno, K1
Murai, Y1
Mita, T1
Suzuki, A1
Otani, K1
Mihara, K1
Yasui, N1
Kondo, T1
Tokinaga, N1
Furukori, H1
Kaneko, S1
Inoue, Y1
Hayashi, K1
Dalezios, Y1
Matsokis, N2
Roberts, AA1
Kellogg, CK2
Giardino, L1
Zanni, M1
Fernandez, M1
Battaglia, A1
Pignataro, O1
Calzà, L1
Korttila, K1
Saarnivaara, L1
Tarkkanen, J1
Himberg, JJ1
Hytönen, M1
Harro, J1
Oreland, L1
Hadjiivanova, C1
Zamdjieva, S1
Petkov, VV1
Guzmán-Godínez, G1
Schliebs, R1
Gravielle, MC1
Flores, V1
Fiszer de Plazas, S1
Schlerka, W1
Reichelt, R1
Hofmann, D1
Födisch, HJ1
Möhler, H1
Knapp, M1
Hebebrand, J1
Zdilar, D1
Rotter, A1
Frostholm, A1
Daval, JL1
Werck, MC1
Nehlig, A1
Pereira de Vasconcelos, A1
Shaw, C1
Cameron, L1
Cynader, M1
Zielinski, B1
Hendrickson, A1
Mhatre, MC1
Fernandes, G1
Ticku, MK1
Primus, RJ1
Deiana, AM1
Salvadori, S1
Cano, J1
Bacon, E2
de Barry, J2
Gombos, G2
Park, D1
Chin, G1
de Blas, AL1
Fares, F1
Weizman, A1
Pick, CG1
Yanai, J1
Gavish, M1
Brüning, G1
Bauer, R1
Baumgarten, HG1
Caboche, J1
Mitrovic, N1
Le Saux, F1
Besson, MJ1
Sauter, A1
Maurin, Y1
Ballinger, WE1
Roujansky, P1
Garrett, KM1
Tabakoff, B1
Komiskey, HL2
Meyers, MB1
Racle, JP1
Benkhadra, A1
Poy, JY1
Gleizal, B1

Reviews

1 review available for flunitrazepam and Aging

ArticleYear
Molecular substrates of anxiety: clues from the heterogeneity of benzodiazepine receptors.
    Life sciences, 1982, Oct-04, Volume: 31, Issue:14

    Topics: Aging; Animals; Anxiety; Benzodiazepines; Binding, Competitive; Brain; Carbolines; Chemical Phenomen

1982

Trials

2 trials available for flunitrazepam and Aging

ArticleYear
Effects of various factors including the CYP2D6 genotype and coadministration of flunitrazepam on the steady-state plasma concentrations of bromperidol and its reduced metabolite.
    Psychopharmacology, 1998, Volume: 135, Issue:4

    Topics: Adolescent; Adult; Aged; Aging; Anti-Anxiety Agents; Antipsychotic Agents; Biotransformation; Cytoch

1998
Effect of increasing amounts of epinephrine during isobaric bupivacaine spinal anesthesia in elderly patients.
    Anesthesia and analgesia, 1987, Volume: 66, Issue:9

    Topics: Aged; Aged, 80 and over; Aging; Anesthesia, Spinal; Autonomic Nerve Block; Blood Pressure; Bupivacai

1987

Other Studies

53 other studies available for flunitrazepam and Aging

ArticleYear
Postnatal development and kinetics of [3H]gaboxadol binding in rat brain: in vitro homogenate binding and quantitative autoradiography.
    Brain research, 2007, Sep-19, Volume: 1170

    Topics: Aging; Animals; Animals, Newborn; Autoradiography; Binding, Competitive; Brain; Brain Chemistry; Flu

2007
Postnatal development of proteins irreversibly labeled by [3H]flunitrazepam.
    Neuroscience letters, 1982, Jul-20, Volume: 31, Issue:1

    Topics: Aging; Animals; Anti-Anxiety Agents; Electrophoresis, Polyacrylamide Gel; Flunitrazepam; Hippocampus

1982
A pharmacokinetic and pharmacodynamic study of flunitrazepam.
    International journal of clinical pharmacology, therapy, and toxicology, 1982, Volume: 20, Issue:12

    Topics: Adult; Aging; Anesthesia, Intravenous; Anti-Anxiety Agents; Female; Flunitrazepam; Humans; Kinetics;

1982
Biochemical development of the human brain. III. Benzodiazepine receptors, free gamma-aminobutyrate (GABA) and other amino acids.
    Journal of neuroscience research, 1982, Volume: 8, Issue:4

    Topics: Adult; Aged; Aging; Amino Acids; Aspartic Acid; Brain; Cerebellum; Female; Flunitrazepam; Frontal Lo

1982
The GABA/benzodiazepine receptor complex in the nervous system of a hypertensive strain of rat.
    Neurochemical research, 1984, Volume: 9, Issue:8

    Topics: Aging; Animals; Brain; Cerebellum; Cerebral Cortex; Flunitrazepam; gamma-Aminobutyric Acid; Glutamat

1984
Benzodiazepine receptors in chick retina: development and cellular localization.
    Brain research, 1981, Feb-09, Volume: 206, Issue:1

    Topics: Aging; Animals; Autoradiography; Chick Embryo; Chickens; Flunitrazepam; Receptors, Drug; Receptors,

1981
Benzodiazepine receptor binding in young, mature and senescent rat brain and kidney.
    Neurobiology of aging, 1981,Summer, Volume: 2, Issue:2

    Topics: Age Factors; Aging; Animals; Brain; Flunitrazepam; Kidney; Male; Rats; Rats, Inbred F344; Receptors,

1981
Ontogeny of high-affinity GABA and benzodiazepine receptors in the rat cerebellum: an autoradiographic study.
    Brain research, 1981, Volume: 254, Issue:4

    Topics: Aging; Animals; Autoradiography; Cerebellum; Clonazepam; Female; Flunitrazepam; gamma-Aminobutyric A

1981
gamma-Aminobutyric acid and benzodiazepine binding sites in audiogenic seizure-susceptible mice.
    Journal of neurochemistry, 1982, Volume: 39, Issue:3

    Topics: Acoustic Stimulation; Aging; Animals; Benzodiazepines; Brain; Cell Membrane; Flunitrazepam; gamma-Am

1982
Memory and postsynaptic cholinergic receptors in aging mice.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:2

    Topics: Aging; Animals; Avoidance Learning; Brain; Brain Mapping; Discrimination Learning; Fear; Flunitrazep

1982
Development of benzodiazepine binding subtypes in three regions of rat brain.
    Brain research, 1983, May-16, Volume: 267, Issue:2

    Topics: Aging; Animals; Binding, Competitive; Brain; Cerebellum; Cerebral Cortex; Flunitrazepam; Hippocampus

1983
Developmental changes in protein carboxylmethylation and in the benzodiazepine receptor proteins in rat brain.
    Biochemical and biophysical research communications, 1983, Nov-15, Volume: 116, Issue:3

    Topics: Aging; Animals; Benzodiazepines; Brain; Cell Membrane; Flunitrazepam; Kinetics; Male; Methionine; Ne

1983
Chronic chlordiazepoxide treatment on adult and newborn rats: effect on the GABA-benzodiazepine receptor complex.
    Advances in biochemical psychopharmacology, 1983, Volume: 38

    Topics: Aging; Animals; Animals, Newborn; Chlordiazepoxide; Female; Flunitrazepam; gamma-Aminobutyric Acid;

1983
[Axillary block of the brachial plexus and flunitrazepam premedication in surgery of the upper limb (study of 1,500 cases)].
    Cahiers d'anesthesiologie, 1984, Volume: 32, Issue:8 Suppl

    Topics: Adolescent; Adult; Aged; Aging; Arm; Axilla; Brachial Plexus; Bupivacaine; Child; Child, Preschool;

1984
[Importance of the ketamine-flunitrazepam combination in elective abortion].
    Cahiers d'anesthesiologie, 1984, Volume: 32, Issue:8 Suppl

    Topics: Abortion, Induced; Adolescent; Adult; Aging; Anesthesia; Consciousness; Female; Flunitrazepam; Human

1984
Effects of Kamikihito, a traditional Chinese medicine, on neurotransmitter receptor binding in the aged rat brain determined by in vitro autoradiography (2): changes in GABAA and benzodiazepine receptor binding.
    Japanese journal of pharmacology, 1994, Volume: 66, Issue:1

    Topics: Aging; Animals; Autoradiography; Brain Chemistry; Drugs, Chinese Herbal; Flunitrazepam; Image Proces

1994
Allosteric modulation of [35S]TBPS-binding in the cerebral cortex of the rat during postnatal development.
    Brain research. Developmental brain research, 1994, Jul-15, Volume: 80, Issue:1-2

    Topics: Aging; Allosteric Regulation; Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compo

1994
Changes in muscarinic cholinergic, PCP, GABAA, D1, and 5-HT2A receptor binding, but not in benzodiazepine receptor binding in the brains of aged rats.
    Life sciences, 1994, Volume: 55, Issue:20

    Topics: Aging; Animals; Autoradiography; Benzazepines; Brain; Flunitrazepam; Male; Phencyclidine; Quinuclidi

1994
Fetal, neonatal and adult expression of benzodiazepine receptor subtypes in human visual cortex.
    European journal of pharmacology, 1993, May-19, Volume: 236, Issue:2

    Topics: Adult; Aged; Aging; Anti-Anxiety Agents; Autoradiography; Embryonic and Fetal Development; Flunitraz

1993
Absence of modifications of the pharmacological properties of the GABAA receptor complex during aging, as assessed in 3- and 24-month-old rat cerebral cortex.
    European journal of pharmacology, 1993, Jun-15, Volume: 246, Issue:1

    Topics: Affinity Labels; Aging; Animals; Anti-Anxiety Agents; Binding, Competitive; Cerebral Cortex; Flunitr

1993
Postnatal development and GABA allosteric modulation of benzodiazepine receptor binding in the vitamin B-6 deficient rat brain.
    Neurochemical research, 1993, Volume: 18, Issue:12

    Topics: Aging; Allosteric Regulation; Animals; Brain; Cell Membrane; Cerebellum; Cerebral Cortex; Female; Fl

1993
Early postnatal treatment with muscimol transiently alters brain GABAA receptors and open-field behavior in rat.
    European journal of pharmacology, 1993, Jan-19, Volume: 230, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Azides; Behavior, Animal; Benzodiazepines; Brain Chemistry; Ethano

1993
GABAA receptor binding in the aging rat inferior colliculus.
    Neuroscience, 1996, Volume: 73, Issue:2

    Topics: Aged; Aging; Animals; Autoradiography; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic

1996
Age-related modifications on the GABAA receptor binding properties from Wistar rat prefrontal cortex.
    Brain research, 1996, Oct-28, Volume: 738, Issue:1

    Topics: Aging; Animals; Benzodiazepines; Binding Sites; Flunitrazepam; GABA Agonists; GABA Modulators; gamma

1996
Granule cell disinhibition in dentate gyrus of genetically seizure susceptible El mice.
    Brain research, 1997, Jan-16, Volume: 745, Issue:1-2

    Topics: Aging; Animals; Anticonvulsants; Bicuculline; Chromatography, High Pressure Liquid; Dentate Gyrus; E

1997
Brain benzodiazepine binding in aged rats.
    Neurochemistry international, 1998, Volume: 32, Issue:2

    Topics: Aging; Animals; Benzodiazepines; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Flunitrazepam;

1998
Synchronous postnatal increase in alpha1 and gamma2L GABA(A) receptor mRNAs and high affinity zolpidem binding across three regions of rat brain.
    Brain research. Developmental brain research, 2000, Jan-03, Volume: 119, Issue:1

    Topics: Aging; Analysis of Variance; Animals; Binding Sites; Binding, Competitive; Brain; Cerebellum; Cerebr

2000
Plasticity of GABA(a) system during ageing: focus on vestibular compensation and possible pharmacological intervention.
    Brain research, 2002, Mar-01, Volume: 929, Issue:1

    Topics: Adaptation, Physiological; Aging; Animals; Brain; Flunitrazepam; GABA Modulators; gamma-Aminobutyric

2002
Effect of age on amnesia and sedation induced by flunitrazepam during local anaesthesia for bronchoscopy.
    British journal of anaesthesia, 1978, Volume: 50, Issue:12

    Topics: Adult; Aged; Aging; Amnesia; Anesthesia, Local; Anti-Anxiety Agents; Bronchoscopy; Flunitrazepam; Hu

1978
Age-related differences of cholecystokinin receptor binding in the rat brain.
    Progress in neuro-psychopharmacology & biological psychiatry, 1992, Volume: 16, Issue:3

    Topics: Aging; Animals; Brain Chemistry; Cerebral Cortex; Flunitrazepam; Hippocampus; In Vitro Techniques; K

1992
Age-related changes in central and peripheral benzodiazepine binding sites.
    Acta physiologica et pharmacologica Bulgarica, 1992, Volume: 18, Issue:1

    Topics: Adrenal Glands; Aging; Animals; Central Nervous System; Cerebellum; Flunitrazepam; Hypothalamus; Kid

1992
Effect of kainic acid administration to prepubescent rats on cholinergic markers in selected brain regions of adult rats.
    Neurochemistry international, 1992, Volume: 21, Issue:3

    Topics: Aging; Animals; Brain; Choline; Choline O-Acetyltransferase; Flunitrazepam; Kainic Acid; Male; Organ

1992
The postnatal development of benzodiazepine receptor sites in the chick optic lobe is modulated by environmental lighting.
    Neurochemistry international, 1992, Volume: 20, Issue:2

    Topics: Aging; Animals; Darkness; Flunitrazepam; Kinetics; Light; Lighting; Optic Lobe, Nonmammalian; Recept

1992
Potency of several type I-benzodiazepine receptor ligands for inhibition of [3H]flunitrazepam binding in different rat brain tissues.
    European journal of pharmacology, 1991, May-02, Volume: 197, Issue:1

    Topics: Aging; Animals; Binding, Competitive; Brain; Flunitrazepam; In Vitro Techniques; Ligands; Rats; Rece

1991
Ontogeny of the benzodiazepine receptor in human brain: fluorographic, immunochemical, and reversible binding studies.
    Journal of neurochemistry, 1991, Volume: 57, Issue:4

    Topics: Adolescent; Aging; Brain; Child; Child, Preschool; Fetus; Flunitrazepam; Humans; Immunoblotting; Inf

1991
Expression of GABAA/benzodiazepine receptor alpha 1-subunit mRNA and [3H]flunitrazepam binding sites during postnatal development of the mouse cerebellum.
    Brain research. Developmental brain research, 1991, Jul-16, Volume: 61, Issue:1

    Topics: Aging; Animals; Autoradiography; Binding Sites; Brain Stem; Cerebellum; Flunitrazepam; Macromolecula

1991
Quantitative autoradiographic study of the postnatal development of benzodiazepine binding sites and their coupling to GABA receptors in the rat brain.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1991, Volume: 9, Issue:4

    Topics: Aging; Animals; Autoradiography; Brain; Flunitrazepam; gamma-Aminobutyric Acid; Organ Specificity; R

1991
Pre- and postnatal development of GABA receptors in Macaca monkey visual cortex.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1991, Volume: 11, Issue:12

    Topics: Aging; Animals; Animals, Newborn; Baclofen; Binding Sites; Corpus Striatum; Embryonic and Fetal Deve

1991
Aging reduces the mRNA of alpha 1 GABAA receptor subunit in rat cerebral cortex.
    European journal of pharmacology, 1991, Oct-14, Volume: 208, Issue:2

    Topics: Aging; Animals; Blotting, Northern; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocycl

1991
Gonadal status and pubertal age influence the responsiveness of the benzodiazepine/GABA receptor complex to environmental challenge in male rats.
    Brain research, 1991, Oct-11, Volume: 561, Issue:2

    Topics: Aging; Animals; Cerebral Cortex; Chlorides; Flunitrazepam; Handling, Psychological; Male; Orchiectom

1991
Age-related decrease in the density of benzodiazepine recognition sites in the brain of the fresh water eel (Anguilla anguilla).
    Neuroscience letters, 1991, Dec-09, Volume: 133, Issue:2

    Topics: Aging; Anguilla; Animals; Brain; Cell Membrane; Flunitrazepam; Kinetics; Receptors, GABA-A

1991
Pharmacologic characterization of GABAA/benzodiazepine receptor in rat hippocampus during aging.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:3

    Topics: Aging; Animals; Binding Sites; Cerebellum; Cerebral Cortex; Culture Techniques; Drug Interactions; F

1991
Differential ontogenesis of type I and II benzodiazepine receptors in mouse cerebellum.
    Brain research. Developmental brain research, 1991, Feb-22, Volume: 58, Issue:2

    Topics: Aging; Animals; Cerebellum; Flunitrazepam; Mice; Models, Biological; Pyridazines; Pyridines; Recepto

1991
Characterization with antibodies of the gamma-aminobutyric acidA/benzodiazepine receptor complex during development of the rat brain.
    Journal of neurochemistry, 1990, Volume: 54, Issue:1

    Topics: Acetylglucosaminidase; Aging; Animals; Antibodies; Antibodies, Monoclonal; Antigen-Antibody Complex;

1990
Effect of prenatal and neonatal chronic exposure to phenobarbital on central and peripheral benzodiazepine receptors.
    Brain research, 1990, Jan-01, Volume: 506, Issue:1

    Topics: Aging; Animals; Brain; Female; Flunitrazepam; Male; Mice; Muscimol; Phenobarbital; Pregnancy; Prenat

1990
Postnatal development of [3H]flunitrazepam and [3H]strychnine binding sites in rat spinal cord localized by quantitative autoradiography.
    Neuroscience letters, 1990, Mar-02, Volume: 110, Issue:1-2

    Topics: Aging; Animals; Flunitrazepam; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Glycine; Re

1990
Postnatal evolution of the gamma-aminobutyric acid/benzodiazepine receptor complex in a model of inherited epilepsy: the quaking mouse.
    Journal of neurochemistry, 1989, Volume: 52, Issue:2

    Topics: Aging; Animals; Brain; Brain Stem; Cerebellum; Diazepam; Diencephalon; Epilepsy; Flunitrazepam; gamm

1989
Neuroreceptor changes in the putamen of alcohol abusers.
    Alcoholism, clinical and experimental research, 1989, Volume: 13, Issue:2

    Topics: Adult; Aging; Alcoholism; Binding, Competitive; Flunitrazepam; Humans; Hypoxia; Putamen; Quinuclidin

1989
Alteration of benzodiazepine receptors in mouse cerebellum following methylazoxymethanol treatment during development.
    Brain research. Developmental brain research, 1989, Jun-01, Volume: 47, Issue:2

    Topics: Aging; Alkylating Agents; Animals; Azo Compounds; Cerebellum; Flunitrazepam; Methylazoxymethanol Ace

1989
The development of type I and type II benzodiazepine receptors in the mouse cortex and cerebellum.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:6

    Topics: Aging; Animals; Anti-Anxiety Agents; Binding, Competitive; Cerebellum; Cerebral Cortex; Female; Flun

1985
Aging: effect on ex-vivo benzodiazepine binding after a diazepam injection.
    Neurochemical research, 1987, Volume: 12, Issue:8

    Topics: Aging; Animals; Anti-Anxiety Agents; Binding, Competitive; Brain; Diazepam; Flunitrazepam; Kinetics;

1987
Aging: effect on the interaction of ethanol and pentobarbital with the benzodiazepine-GABA receptor-ionophore complex.
    Brain research, 1985, Sep-23, Volume: 343, Issue:2

    Topics: Aging; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Ethanol; Flunitr

1985
Comparison of benzodiazepine receptors in cerebellum and inferior colliculus.
    Journal of neurochemistry, 1986, Volume: 47, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Carbolines; Cell Membrane; Cerebellum; Clonazepam; Diazepam; Fluni

1986