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flunitrazepam and Absence Status

flunitrazepam has been researched along with Absence Status in 9 studies

Flunitrazepam: A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
flunitrazepam : A 1,4-benzodiazepinone that is nitrazepam substituted by a methyl group at position 1 and by a fluoro group at position 2'. It is a potent hypnotic, sedative, and amnestic drug used to treat chronic insomnia.

Research Excerpts

ExcerptRelevanceReference
" We have now applied autoradiography to study properties of GABA(A)/benzodiazepine receptors in 9-day-old rats acutely (6 h) and sub-acutely (7 days) after kainic acid-induced status epilepticus by analyzing displacement of [(3)H]flunitrazepam binding by zolpidem, a ligand selective for the alpha1beta2gamma2 receptor subtype."7.74Status epilepticus alters zolpidem sensitivity of [3H]flunitrazepam binding in the developing rat brain. ( Holopainen, IE; Kukko-Lukjanov, TK; Laurén, HB; Lopez-Picon, FR; Uusi-Oukari, M, 2007)
"Flunitrazepam (FZP) was administered intravenously, with success, to two patients with status epilepticus."7.67Intravenous flunitrazepam for status epilepticus. ( Akagi, M; Nagaura, T; Nishigaki, T; Sakata, N; Sumi, K, 1989)
"Two cases of status epilepticus are reported, whose seizures responded well to the injection of flunitrazepam."7.67Intravenous injection of flunitrazepam for status epilepticus in children--two case reports. ( Mimaki, T; Ono, J; Tagawa, T; Tanaka, J, 1988)
" We have now applied autoradiography to study properties of GABA(A)/benzodiazepine receptors in 9-day-old rats acutely (6 h) and sub-acutely (7 days) after kainic acid-induced status epilepticus by analyzing displacement of [(3)H]flunitrazepam binding by zolpidem, a ligand selective for the alpha1beta2gamma2 receptor subtype."3.74Status epilepticus alters zolpidem sensitivity of [3H]flunitrazepam binding in the developing rat brain. ( Holopainen, IE; Kukko-Lukjanov, TK; Laurén, HB; Lopez-Picon, FR; Uusi-Oukari, M, 2007)
"Effects of status epilepticus and chronic temporal lobe epilepsy on benzodiazepine (BDZ) receptor binding in the rat brain were evaluated using in vitro autoradiography, 24 h and 40 days after kainic acid (KA) administration (10 mg/kg i."3.70Characterization of benzodiazepine receptor binding following kainic acid administration: an autoradiography study in rats. ( Ondarza-Rovira, R; Rocha, L, 1999)
" Three cases of convulsive status epilepticus (CSE) following abrupt discontinuation of long-term use of 25 mg of lorazepam in one patient and more than 20 mg of flunitrazepam in two patients are presented; they were non-epileptics and free of other high-risk factors for seizures."3.70Convulsive status epilepticus following abrupt high-dose benzodiazepine discontinuation. ( Angelopoulos, EK; Chioni, A; Daskalopoulou, EG; Gatzonis, SD; Mantouvalos, V; Siafakas, A; Zournas, C, 2000)
" Status epilepticus was induced in immature animals by administration of kainic acid (7 mg/kg intraperitoneal), whereas adults rats received saline."3.70Characterization of benzodiazepine receptor binding in immature rat brain after kainic acid administration. ( Gaona, A; González-Trujano, ME; Jiménez, G; Ondarza, R; Rocha, L, 2000)
"Flunitrazepam (FZP) was administered intravenously, with success, to two patients with status epilepticus."3.67Intravenous flunitrazepam for status epilepticus. ( Akagi, M; Nagaura, T; Nishigaki, T; Sakata, N; Sumi, K, 1989)
"Two cases of status epilepticus are reported, whose seizures responded well to the injection of flunitrazepam."3.67Intravenous injection of flunitrazepam for status epilepticus in children--two case reports. ( Mimaki, T; Ono, J; Tagawa, T; Tanaka, J, 1988)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's3 (33.33)18.2507
2000's4 (44.44)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kawakami, Y1
Matsumoto, Y1
Hashimoto, K1
Kuwabara, K1
Hirata, K1
Fujita, T1
Fujino, O1
Laurén, HB1
Lopez-Picon, FR1
Kukko-Lukjanov, TK1
Uusi-Oukari, M1
Holopainen, IE1
Primavera, A1
Cocito, L1
Briefer, JP1
Unger, PF1
Rocha, L2
Ondarza-Rovira, R1
Gatzonis, SD1
Angelopoulos, EK1
Daskalopoulou, EG1
Mantouvalos, V1
Chioni, A1
Zournas, C1
Siafakas, A1
González-Trujano, ME1
Jiménez, G1
Gaona, A1
Ondarza, R1
Sumi, K1
Nagaura, T1
Sakata, N1
Nishigaki, T1
Akagi, M1
Ono, J1
Mimaki, T1
Tagawa, T1
Tanaka, J1

Other Studies

9 other studies available for flunitrazepam and Absence Status

ArticleYear
Treatment with flunitrazepam of continuous spikes and waves during slow wave sleep (CSWS) in children.
    Seizure, 2007, Volume: 16, Issue:2

    Topics: Anticonvulsants; Child; Electroencephalography; Epilepsy; Flunitrazepam; Humans; Landau-Kleffner Syn

2007
Status epilepticus alters zolpidem sensitivity of [3H]flunitrazepam binding in the developing rat brain.
    Neuroscience, 2007, May-11, Volume: 146, Issue:2

    Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Autoradiography; Brain; Disease Models

2007
Acute confusion in a chronic benzodiazepine patient. Withdrawal-related nonconvulsive status epilepticus misdiagnosed as acute intoxication.
    General hospital psychiatry, 1995, Volume: 17, Issue:6

    Topics: Aged; Anti-Anxiety Agents; Anxiety Disorders; Confusion; Diagnostic Errors; Drug Overdose; Flunitraz

1995
[Emergency medicine for the practitioner: coma and confusional states].
    Revue medicale de la Suisse romande, 1997, Volume: 117, Issue:4

    Topics: Adult; Aged; Anti-Anxiety Agents; Cognition Disorders; Coma; Epilepsy, Absence; Family Practice; Fem

1997
Characterization of benzodiazepine receptor binding following kainic acid administration: an autoradiography study in rats.
    Neuroscience letters, 1999, Mar-12, Volume: 262, Issue:3

    Topics: Animals; Autoradiography; Brain; Flunitrazepam; Kainic Acid; Male; Neurons; Organ Specificity; Rats;

1999
Convulsive status epilepticus following abrupt high-dose benzodiazepine discontinuation.
    Drug and alcohol dependence, 2000, Apr-01, Volume: 59, Issue:1

    Topics: Adult; Anti-Anxiety Agents; Dose-Response Relationship, Drug; Epilepsy, Tonic-Clonic; Female; Flunit

2000
Characterization of benzodiazepine receptor binding in immature rat brain after kainic acid administration.
    Epilepsia, 2000, Volume: 41 Suppl 6

    Topics: Age Factors; Animals; Autoradiography; Brain; Cerebral Cortex; Disease Models, Animal; Epilepsy, Tem

2000
Intravenous flunitrazepam for status epilepticus.
    Acta paediatrica Japonica : Overseas edition, 1989, Volume: 31, Issue:5

    Topics: Child; Child, Preschool; Electroencephalography; Female; Flunitrazepam; Humans; Injections, Intraven

1989
Intravenous injection of flunitrazepam for status epilepticus in children--two case reports.
    Brain & development, 1988, Volume: 10, Issue:5

    Topics: Electroencephalography; Female; Flunitrazepam; Humans; Infant; Infant, Newborn; Injections, Intraven

1988