flunarizine and Status-Epilepticus

flunarizine has been researched along with Status-Epilepticus* in 2 studies

Other Studies

2 other study(ies) available for flunarizine and Status-Epilepticus

ArticleYear
Patient with unusual alternating hemiplegia.
    Pediatric neurology, 1994, Volume: 10, Issue:2

    A patient with unusual alternating hemiplegia in childhood is reported. The frequency of hemiplegic episodes was lower than that in other reported patients. Interictal positron emission tomography revealed decreased cerebral blood flow in the left hemisphere. After cerebral angiography, postanesthetic irritability occurred which evolved into coma with hemiplegic episodes. We believe that cerebral angiography in a child with alternating hemiplegia may cause hemiplegic episodes and coma. The episodes disappeared almost completely for 6 years after treatment with flunarizine, thus indicating the benefit of the medication for the treatment of alternating hemiplegia.

    Topics: Basal Ganglia; Cerebral Angiography; Cerebral Cortex; Child; Coma; Dominance, Cerebral; Electroencephalography; Epilepsy, Tonic-Clonic; Female; Flunarizine; Follow-Up Studies; Hemiplegia; Humans; Ischemic Attack, Transient; Recurrence; Regional Blood Flow; Status Epilepticus; Tomography, Emission-Computed

1994
Alternating hemiplegia of childhood: a study of 10 patients and results of flunarizine treatment.
    Neurology, 1993, Volume: 43, Issue:1

    Alternating hemiplegia of childhood is a rare syndrome characterized by onset before 18 months of age of frequent attacks of alternating paralysis, transient ocular palsies, nystagmus, choreoathetosis, and autonomic dysfunction. We describe features of 10 patients followed for up to 27 years. The mechanism of alternating hemiplegia remains unknown but an association to migraine is suspected because of the strong family history of migraine and aura symptoms in some patients. We treated nine patients with flunarizine, a calcium channel blocker, for up to 5 years; they showed a reduction in duration of the hemiplegic attacks, but the episodes ceased completely in only one patient. With long-term follow-up, the persistent motor, movement, and cognitive deficits are more apparent. It is not certain if the flunarizine alters this course.

    Topics: Adolescent; Adult; Autonomic Nervous System Diseases; Child; Child, Preschool; Electroencephalography; Female; Flunarizine; Hemiplegia; Humans; Magnetic Resonance Spectroscopy; Male; Muscles; Nystagmus, Pathologic; Organophosphorus Compounds; Recurrence; Retrospective Studies; Status Epilepticus; Syndrome

1993