flunarizine and Ehlers-Danlos-Syndrome

Ehlers-Danlos syndrome is a rare inherited illness, which includes an autosomal dominant and also a recessive X-linked variant. Its main clinical characteristic is a generalised connective tissue involving collagen and elastin, causing fragile and hyperextensible skin, loose jointedness and bruising. Many clinical subtypes are described, each of a different severity degree pattern. The correlation of this syndrome and headache disorders is rare. In this paper we describe the case of a young woman with Type II (less severe) Ehlers-Danlos Syndrome and headache.

Topics: Adult; Brain; Calcium Channel Blockers; Ehlers-Danlos Syndrome; Female; Flunarizine; Headache; Humans; Magnetic Resonance Imaging; Migraine Disorders; Mouth; Radiography