flunarizine and Dementia

flunarizine has been researched along with Dementia* in 4 studies

Trials

3 trial(s) available for flunarizine and Dementia

Article	Year
Cyclandelate versus flunarizine. A double-blind study in a selected group of patients with dementia. Drugs, 1987, Volume: 33 Suppl 2 A double-blind, double-dummy clinical trial was conducted in which the efficacy of cyclandelate 1600 mg daily was compared with that of flunarizine 10mg daily in 40 patients (25 men and 15 women) with dementia of cerebrovascular origin. Parameters were assessed before treatment, and after 45 and 90 days of therapy. At 90 days, significant improvements were observed in patients given cyclandelate in measurements of P100 latency in the left eye, neurological impairment, dementia scores, ischaemia scores, Gottfries mental deterioration scale, Hamilton depression scores, short term visual memory, long term memory, Bender-Gestalt test and Koh's blocks test. In flunarizine recipients, improvements were observed in neurological impairment, ischaemia scores, Gottfries scale and Hamilton depression scores. Patients treated with cyclandelate showed significantly greater ameliorations in symptoms as assessed by the ischaemia scale, evoked visual potential, visual memory and Koh's block test compared with those given flunarizine. However, in none of the parameters was flunarizine superior to cyclandelate. Topics: Aged; Cerebrovascular Disorders; Clinical Trials as Topic; Cyclandelate; Dementia; Double-Blind Method; Electroencephalography; Evoked Potentials, Auditory; Female; Flunarizine; Humans; Male; Mandelic Acids; Memory; Middle Aged; Psychiatric Status Rating Scales; Random Allocation	1987
[Favorable effect on the symptoms of aging. Results of some studies]. Fortschritte der Medizin. Supplement : die Kongressinformation fur die Praxis, 1986, Volume: 1 Topics: Calcium Channel Blockers; Cinnarizine; Clinical Trials as Topic; Dementia; Flunarizine; Humans	1986
[Brain organic psychosyndrome. More satisfaction with flunarizine]. Fortschritte der Medizin. Supplement : die Kongressinformation fur die Praxis, 1985, Volume: 8 Topics: Aged; Calcium Channel Blockers; Cinnarizine; Clinical Trials as Topic; Dementia; Double-Blind Method; Flunarizine; Humans; Middle Aged	1985

Other Studies

1 other study(ies) available for flunarizine and Dementia

Article	Year
[Use of flunarizine in mild-to-severe senile cerebral deterioration]. La Clinica terapeutica, 1990, Mar-31, Volume: 132, Issue:6 Within the framework of multifactorial etiology the use of calcium entry blockers as a complementary measure in the management of moderate-to-severe senile brain deterioration has been studied. Clinical study of twelve flunarizine-treated patients has yielded promising evidence in favor of vasoactive drugs as adjuvants to treatment with psychoactive drugs. Further studies should lend support to this hypothesis. Topics: Aged; Dementia; Drug Evaluation; Flunarizine; Humans; Male; Psychiatric Status Rating Scales; Time Factors	1990

Article

Year

[Use of flunarizine in mild-to-severe senile cerebral deterioration].

La Clinica terapeutica, 1990, Mar-31, Volume: 132, Issue:6

Within the framework of multifactorial etiology the use of calcium entry blockers as a complementary measure in the management of moderate-to-severe senile brain deterioration has been studied. Clinical study of twelve flunarizine-treated patients has yielded promising evidence in favor of vasoactive drugs as adjuvants to treatment with psychoactive drugs. Further studies should lend support to this hypothesis.

Topics: Aged; Dementia; Drug Evaluation; Flunarizine; Humans; Male; Psychiatric Status Rating Scales; Time Factors

1990