flumethasone-pivalate and Postoperative-Complications

Clinicians often prescribe otic drops anecdotally to try and clear grommets blocked with blood. We carried out an in vitro double-blind randomized controlled study comparing the efficacy of sodium bicarbonate, Locorten Vioform and olive oil drops in clearing Shah grommets placed in 'artificial ears' and blocked with blood in a standardized fashion. There were 33 grommets in each group, and drops were inserted three times a day for 7 days. Olive oil drops cleared 17 of 33 (51.51%), Locorten Vioform cleared one of 33 (3%) and sodium bicarbonate cleared zero of 33 (0%) blocked grommets. Statistical comparison between pairs indicates that olive oil was significantly better than both Locorten Vioform (P < 0.001) and sodium bicarbonate drops (P < 0.001) at clearing grommets blocked with blood.

Topics: Administration, Topical; Anti-Infective Agents, Local; Anti-Inflammatory Agents; Clioquinol; Equipment Failure; Flumethasone; Humans; Middle Ear Ventilation; Models, Anatomic; Olive Oil; Plant Oils; Postoperative Complications; Prospective Studies; Sodium Bicarbonate