flumazenil has been researched along with Tuberous Sclerosis in 3 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Tuberous Sclerosis: Autosomal dominant neurocutaneous syndrome classically characterized by MENTAL RETARDATION; EPILEPSY; and skin lesions (e.g., adenoma sebaceum and hypomelanotic macules). There is, however, considerable heterogeneity in the neurologic manifestations. It is also associated with cortical tuber and HAMARTOMAS formation throughout the body, especially the heart, kidneys, and eyes. Mutations in two loci TSC1 and TSC2 that encode hamartin and tuberin, respectively, are associated with the disease.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (33.33) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Mori, K | 1 |
Mori, T | 1 |
Toda, Y | 1 |
Fujii, E | 1 |
Miyazaki, M | 1 |
Harada, M | 1 |
Kagami, S | 1 |
Kuki, I | 1 |
Kawawaki, H | 1 |
Oba, S | 1 |
Okazaki, S | 1 |
Ikeda, H | 1 |
Tomiwa, K | 1 |
Fujita, M | 1 |
Hashikawa, K | 1 |
Nagai, T | 1 |
Kodaka, R | 1 |
Uehara, T | 1 |
Nishimura, T | 1 |
3 other studies available for flumazenil and Tuberous Sclerosis
Article | Year |
---|---|
Decreased benzodiazepine receptor and increased GABA level in cortical tubers in tuberous sclerosis complex.
Topics: Aspartic Acid; Brain; Case-Control Studies; Child; Child, Preschool; Female; Flumazenil; gamma-Amino | 2012 |
[123I iomazenil SPECT and identification of the epileptogenic tubers in patients with tuberous sclerosis].
Topics: Adolescent; Adult; Cerebral Cortex; Child; Child, Preschool; Epilepsies, Partial; Female; Flumazenil | 2008 |
Decrease of the central type benzodiazepine receptor in cortical tubers in a patient with tuberous sclerosis.
Topics: Adolescent; Cerebral Cortex; Flumazenil; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; M | 1997 |