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flumazenil and Tuberous Sclerosis

flumazenil has been researched along with Tuberous Sclerosis in 3 studies

Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.

Tuberous Sclerosis: Autosomal dominant neurocutaneous syndrome classically characterized by MENTAL RETARDATION; EPILEPSY; and skin lesions (e.g., adenoma sebaceum and hypomelanotic macules). There is, however, considerable heterogeneity in the neurologic manifestations. It is also associated with cortical tuber and HAMARTOMAS formation throughout the body, especially the heart, kidneys, and eyes. Mutations in two loci TSC1 and TSC2 that encode hamartin and tuberin, respectively, are associated with the disease.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mori, K1
Mori, T1
Toda, Y1
Fujii, E1
Miyazaki, M1
Harada, M1
Kagami, S1
Kuki, I1
Kawawaki, H1
Oba, S1
Okazaki, S1
Ikeda, H1
Tomiwa, K1
Fujita, M1
Hashikawa, K1
Nagai, T1
Kodaka, R1
Uehara, T1
Nishimura, T1

Other Studies

3 other studies available for flumazenil and Tuberous Sclerosis

ArticleYear
Decreased benzodiazepine receptor and increased GABA level in cortical tubers in tuberous sclerosis complex.
    Brain & development, 2012, Volume: 34, Issue:6

    Topics: Aspartic Acid; Brain; Case-Control Studies; Child; Child, Preschool; Female; Flumazenil; gamma-Amino

2012
[123I iomazenil SPECT and identification of the epileptogenic tubers in patients with tuberous sclerosis].
    No to hattatsu = Brain and development, 2008, Volume: 40, Issue:1

    Topics: Adolescent; Adult; Cerebral Cortex; Child; Child, Preschool; Epilepsies, Partial; Female; Flumazenil

2008
Decrease of the central type benzodiazepine receptor in cortical tubers in a patient with tuberous sclerosis.
    Clinical nuclear medicine, 1997, Volume: 22, Issue:2

    Topics: Adolescent; Cerebral Cortex; Flumazenil; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; M

1997