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flumazenil and Stress Disorders, Post-Traumatic

flumazenil has been researched along with Stress Disorders, Post-Traumatic in 5 studies

Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.

Stress Disorders, Post-Traumatic: A class of traumatic stress disorders with symptoms that last more than one month.

Research Excerpts

ExcerptRelevanceReference
"Patients with PTSD have a changed sensitivity to GABA-A receptor active substances."1.43Women with PTSD have a changed sensitivity to GABA-A receptor active substances. ( Bäckström, T; Helström, L; Möller, AT; Nyberg, S; Söndergaard, HP, 2016)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reuveni, I1
Nugent, AC1
Gill, J1
Vythilingam, M1
Carlson, PJ1
Lerner, A1
Neumeister, A1
Charney, DS1
Drevets, WC1
Bonne, O1
Möller, AT1
Bäckström, T1
Nyberg, S1
Söndergaard, HP1
Helström, L1
Fujita, M1
Southwick, SM1
Denucci, CC1
Zoghbi, SS1
Dillon, MS1
Baldwin, RM1
Bozkurt, A1
Kugaya, A1
Verhoeff, NP1
Seibyl, JP1
Innis, RB1
Geuze, E1
van Berckel, BN1
Lammertsma, AA1
Boellaard, R1
de Kloet, CS1
Vermetten, E1
Westenberg, HG1
Coupland, NJ1
Lillywhite, A1
Bell, CE1
Potokar, JP1
Nutt, DJ1

Trials

2 trials available for flumazenil and Stress Disorders, Post-Traumatic

ArticleYear
Central type benzodiazepine receptors in Gulf War veterans with posttraumatic stress disorder.
    Biological psychiatry, 2004, Jul-15, Volume: 56, Issue:2

    Topics: Adult; Combat Disorders; Female; Flumazenil; Humans; Iodine Radioisotopes; Life Change Events; Male;

2004
A pilot controlled study of the effects of flumazenil in posttraumatic stress disorder.
    Biological psychiatry, 1997, May-01, Volume: 41, Issue:9

    Topics: Adult; Arousal; Combat Disorders; Double-Blind Method; Female; Flumazenil; GABA Modulators; Humans;

1997

Other Studies

3 other studies available for flumazenil and Stress Disorders, Post-Traumatic

ArticleYear
Altered cerebral benzodiazepine receptor binding in post-traumatic stress disorder.
    Translational psychiatry, 2018, 10-04, Volume: 8, Issue:1

    Topics: Adult; Carbon Radioisotopes; Cerebral Cortex; Female; Flumazenil; Gyrus Cinguli; Humans; Male; Parie

2018
Women with PTSD have a changed sensitivity to GABA-A receptor active substances.
    Psychopharmacology, 2016, Volume: 233, Issue:11

    Topics: Adolescent; Adult; Anxiety; Diagnostic and Statistical Manual of Mental Disorders; Diazepam; Female;

2016
Reduced GABAA benzodiazepine receptor binding in veterans with post-traumatic stress disorder.
    Molecular psychiatry, 2008, Volume: 13, Issue:1

    Topics: Adult; Brain Mapping; Carbon Radioisotopes; Case-Control Studies; Flumazenil; Functional Laterality;

2008