flumazenil has been researched along with Stomach Ulcer in 5 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Stomach Ulcer: Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effects of CGS 9896, a partial benzodiazepine agonist, and chlordiazepoxide, a full benzodiazepine agonist, on stress-induced gastric ulcers as well as blood glucose were compared." | 3.68 | Effect of CGS 9896 on stress-induced gastric ulcer in rat. ( Karim, KH; Najim, RA, 1990) |
| "The effects of bilateral microinjections of chlordiazepoxide and GABA into the central amygdalar nucleus on gastric ulcer formation induced by cold-restraint were examined in chronically implanted Wistar rats." | 3.67 | The GABA/benzodiazepine receptor complex in the central amygdalar nucleus and stress ulcers in rats. ( Hebert, MA; Henke, PG; Ray, A; Sullivan, RM; Trimper, JM, 1989) |
| "Flumazenil alone was found to aggravate ethanol-induced gastric damage (200-400 microg)." | 1.31 | Benzodiazepines protect against ethanol-induced gastric mucosal damage in vitro. ( Al-Mulla Hummadi, YM; Farjou, IB; Najim, RA, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Najim, RA | 3 |
| Karim, KH | 2 |
| Al-Mulla Hummadi, YM | 1 |
| Farjou, IB | 1 |
| Sullivan, RM | 1 |
| Henke, PG | 1 |
| Ray, A | 1 |
| Hebert, MA | 1 |
| Trimper, JM | 1 |
| Kunchandy, J | 1 |
| Kulkarni, SK | 1 |
5 other studies available for flumazenil and Stomach Ulcer
| Article | Year |
|---|---|
Prevention of ethanol-induced gastric damage by the imidazobenzodiazepines Ro 15-4513 and Ro 15-3505 in rats.
Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Ethanol; Flumazenil; Male; Rats; Rats, Wistar; | 1993 |
Benzodiazepines protect against ethanol-induced gastric mucosal damage in vitro.
Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Central Nervous System Depressants; Clonazepam; E | 2001 |
Effect of CGS 9896 on stress-induced gastric ulcer in rat.
Topics: Animals; Benzodiazepines; Chlordiazepoxide; Cold Temperature; Drug Therapy, Combination; Flumazenil; | 1990 |
The GABA/benzodiazepine receptor complex in the central amygdalar nucleus and stress ulcers in rats.
Topics: Amygdala; Animals; Arousal; Chlordiazepoxide; Dose-Response Relationship, Drug; Flumazenil; Male; Ra | 1989 |
Involvement of central type benzodiazepine and GABAA receptor in the protective effect of benzodiazepines in stress-induced gastric ulcers in rats.
Topics: Animals; Anti-Anxiety Agents; Female; Flumazenil; Gastric Mucosa; Male; Rats; Rats, Inbred Strains; | 1987 |