flumazenil has been researched along with Reperfusion Injury in 5 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Reperfusion hyperalgesia manifested as a decrease in tail flick latency, following tail immersion in 49 degrees C water, after the release of the tourniquet." | 1.29 | Attenuation of reperfusion hyperalgesia in the rat by systemic administration of benzodiazepines. ( Cartmell, SM; Mitchell, D, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rojas, S | 1 |
| Martín, A | 1 |
| Pareto, D | 1 |
| Herance, JR | 1 |
| Abad, S | 1 |
| Ruíz, A | 1 |
| Flotats, N | 1 |
| Gispert, JD | 1 |
| Llop, J | 1 |
| Gómez-Vallejo, V | 1 |
| Planas, AM | 1 |
| Heiss, WD | 1 |
| Abe, K | 1 |
| Kashiwagi, Y | 1 |
| Tokumura, M | 1 |
| Hosoi, R | 1 |
| Hatazawa, J | 1 |
| Inoue, O | 1 |
| Giffard, C | 1 |
| Landeau, B | 1 |
| Kerrouche, N | 1 |
| Young, AR | 1 |
| Barré, L | 1 |
| Baron, JC | 1 |
| Cartmell, SM | 1 |
| Mitchell, D | 1 |
1 review available for flumazenil and Reperfusion Injury
| Article | Year |
|---|---|
The ischemic penumbra: how does tissue injury evolve?
Topics: Animals; Brain; Brain Edema; Brain Ischemia; Cats; Cerebral Infarction; Cerebrovascular Circulation; | 2012 |
4 other studies available for flumazenil and Reperfusion Injury
| Article | Year |
|---|---|
Positron emission tomography with 11C-flumazenil in the rat shows preservation of binding sites during the acute phase after 2 h-transient focal ischemia.
Topics: Acute Disease; Animals; Binding Sites; Brain Ischemia; Disease Models, Animal; Flumazenil; Male; Ner | 2011 |
Discrepancy between cell injury and benzodiazepine receptor binding after transient middle cerebral artery occlusion in rats.
Topics: Animals; Autoradiography; Benzazepines; Benzilates; Binding Sites; Binding, Competitive; Cerebral Co | 2004 |
Decreased chronic-stage cortical 11C-flumazenil binding after focal ischemia-reperfusion in baboons: a marker of selective neuronal loss?
Topics: Animals; Brain Ischemia; Carbon Isotopes; Cerebral Cortex; Chronic Disease; Flumazenil; Hemodynamics | 2008 |
Attenuation of reperfusion hyperalgesia in the rat by systemic administration of benzodiazepines.
Topics: Animals; Behavior, Animal; Benzodiazepines; Chlordiazepoxide; Depression, Chemical; Diazepam; Dose-R | 1993 |