flumazenil has been researched along with Panic Attacks in 23 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We hypothesised that RTD (compared with the control drink) would result in an increase in anxiety symptoms when provoked by a panicogenic challenge with the benzodiazepine antagonist, flumazenil." | 9.15 | Rapid tryptophan depletion following cognitive behavioural therapy for panic disorder. ( Adrover, M; Argyropoulos, S; Bell, C; Frampton, C; Hince, D; Hood, S; Nash, J; Nutt, D; Potokar, J; Rich, A, 2011) |
| "Flumazenil is a benzodiazepine receptor antagonist thought to be panicogenic in patients with panic disorder but not in control subjects." | 9.09 | Behavioral, neuroendocrine, and cardiovascular response to flumazenil: no evidence for an altered benzodiazepine receptor sensitivity in panic disorder. ( Holsboer, F; Kellner, M; Ströhle, A; Wiedemann, K, 1999) |
| "Flumazenil is a benzodiazepine receptor antagonist that has been reported to provoke panic attacks in patients with panic disorder." | 9.08 | Effect of flumazenil in lactate-sensitive patients with panic disorder. ( Holsboer, F; Kellner, M; Ströhle, A; Wiedemann, K; Yassouridis, A, 1998) |
| " We hypothesised that RTD (compared with the control drink) would result in an increase in anxiety symptoms when provoked by a panicogenic challenge with the benzodiazepine antagonist, flumazenil." | 5.15 | Rapid tryptophan depletion following cognitive behavioural therapy for panic disorder. ( Adrover, M; Argyropoulos, S; Bell, C; Frampton, C; Hince, D; Hood, S; Nash, J; Nutt, D; Potokar, J; Rich, A, 2011) |
| "Flumazenil is a benzodiazepine receptor antagonist thought to be panicogenic in patients with panic disorder but not in control subjects." | 5.09 | Behavioral, neuroendocrine, and cardiovascular response to flumazenil: no evidence for an altered benzodiazepine receptor sensitivity in panic disorder. ( Holsboer, F; Kellner, M; Ströhle, A; Wiedemann, K, 1999) |
| "The benzodiazepine antagonist, flumazenil, can provoke panic attacks in some panic disorder patients." | 5.09 | Flumazenil challenge in social phobia. ( Bell, C; Coupland, NJ; Dorkins, E; Nutt, DJ; Potokar, JP, 2000) |
| "Flumazenil is a benzodiazepine receptor antagonist that has been reported to provoke panic attacks in patients with panic disorder." | 5.08 | Effect of flumazenil in lactate-sensitive patients with panic disorder. ( Holsboer, F; Kellner, M; Ströhle, A; Wiedemann, K; Yassouridis, A, 1998) |
| " We employed flumazenil radiolabeled with carbon 11, a radioligand that labels the benzodiazepine site on the GABA(A) receptor, and fully quantitative, high-sensitivity PET to test the hypothesis that central benzodiazepine site binding is decreased in medication-free patients with panic disorder." | 3.70 | Decreased brain GABA(A)-benzodiazepine receptor binding in panic disorder: preliminary results from a quantitative PET study. ( Bell, CJ; Cunningham, VJ; Jones, T; Liddle, PF; Malizia, AL; Nutt, DJ, 1998) |
| "Flumazenil is a relatively pure benzodiazepine/GABAA antagonist with limited intrinsic activity." | 2.68 | Effects of the benzodiazepine antagonist flumazenil in PTSD. ( Bremner, JD; Charney, DS; Heninger, GR; Krystal, JH; Nagy, LM; Nicolaou, AL; Randall, PK, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (56.52) | 18.2507 |
| 2000's | 8 (34.78) | 29.6817 |
| 2010's | 2 (8.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bernik, M | 1 |
| Ramos, RT | 1 |
| Hetem, LAB | 1 |
| Graeff, F | 1 |
| Hasler, G | 1 |
| Nugent, AC | 1 |
| Carlson, PJ | 1 |
| Carson, RE | 1 |
| Geraci, M | 1 |
| Drevets, WC | 1 |
| Suzuki, K | 1 |
| Takano, T | 1 |
| Fujiyama, K | 1 |
| Tanabe, Y | 1 |
| Matsuoka, H | 1 |
| Bell, C | 3 |
| Hood, S | 2 |
| Potokar, J | 2 |
| Nash, J | 2 |
| Adrover, M | 2 |
| Frampton, C | 1 |
| Hince, D | 1 |
| Rich, A | 2 |
| Argyropoulos, S | 2 |
| Nutt, D | 2 |
| Bell, EC | 1 |
| Baker, GB | 1 |
| Poag, C | 1 |
| Bellavance, F | 1 |
| Khudabux, J | 1 |
| Le Mellédo, JM | 2 |
| Cameron, OG | 1 |
| Huang, GC | 1 |
| Nichols, T | 1 |
| Koeppe, RA | 1 |
| Minoshima, S | 1 |
| Rose, D | 1 |
| Frey, KA | 1 |
| Randall, PK | 1 |
| Bremner, JD | 2 |
| Krystal, JH | 1 |
| Nagy, LM | 1 |
| Heninger, GR | 1 |
| Nicolaou, AL | 1 |
| Charney, DS | 2 |
| Kuikka, JT | 1 |
| Pitkänen, A | 1 |
| Lepola, U | 1 |
| Partanen, K | 1 |
| Vainio, P | 1 |
| Bergström, KA | 1 |
| Wieler, HJ | 1 |
| Kaiser, KP | 1 |
| Mittelbach, L | 1 |
| Koponen, H | 1 |
| Bradwejn, J | 1 |
| Koszycki, D | 1 |
| Couëtoux du Tertre, A | 1 |
| Paradis, M | 1 |
| Bourin, M | 1 |
| Schlegel, S | 1 |
| Steinert, H | 1 |
| Bockisch, A | 1 |
| Hahn, K | 1 |
| Schloesser, R | 1 |
| Benkert, O | 1 |
| Ströhle, A | 2 |
| Kellner, M | 2 |
| Yassouridis, A | 1 |
| Holsboer, F | 2 |
| Wiedemann, K | 2 |
| Maddock, RJ | 1 |
| Bernik, MA | 1 |
| Gorenstein, C | 1 |
| Vieira Filho, AH | 1 |
| Malizia, AL | 3 |
| Cunningham, VJ | 1 |
| Bell, CJ | 2 |
| Liddle, PF | 1 |
| Jones, T | 1 |
| Nutt, DJ | 4 |
| Morimoto, K | 1 |
| Lawson, C | 1 |
| Wilson, S | 1 |
| Innis, RB | 1 |
| White, T | 1 |
| Fujita, M | 1 |
| Silbersweig, D | 1 |
| Goddard, AW | 1 |
| Staib, L | 1 |
| Stern, E | 1 |
| Cappiello, A | 1 |
| Woods, S | 1 |
| Baldwin, R | 1 |
| Coupland, NJ | 2 |
| Potokar, JP | 1 |
| Dorkins, E | 1 |
| Van Driel, M | 1 |
| Lott, P | 1 |
| Jhangri, GS | 1 |
| Forshall, S | 1 |
3 reviews available for flumazenil and Panic Attacks
| Article | Year |
|---|---|
The neurobiology of social phobia.
Topics: Brain; Caffeine; Carbon Dioxide; Cholecystokinin; Epinephrine; Female; Flumazenil; Human Growth Horm | 1999 |
[Benzodiazepine receptor imaging in the brain: recent developments and clinical validity].
Topics: Brain; Carbon Radioisotopes; Epilepsy, Temporal Lobe; Flumazenil; Humans; Iodine Radioisotopes; Pani | 1999 |
What do brain imaging studies tell us about anxiety disorders?
Topics: Anxiety Disorders; Brain; Carbon Radioisotopes; Cerebrovascular Circulation; Flumazenil; Humans; Pan | 1999 |
12 trials available for flumazenil and Panic Attacks
| Article | Year |
|---|---|
Effect of single doses of pindolol and d-fenfluramine on flumazenil-induced anxiety in panic disorder patients.
Topics: Adult; Anxiety; Female; Fenfluramine; Flumazenil; GABA Modulators; Humans; Male; Middle Aged; Panic | 2019 |
Rapid tryptophan depletion following cognitive behavioural therapy for panic disorder.
Topics: Adult; Anxiety; Cognitive Behavioral Therapy; Cross-Over Studies; Double-Blind Method; Female; Fluma | 2011 |
Response to flumazenil in the late luteal phase and follicular phase of the menstrual cycle in healthy control females.
Topics: Adult; Double-Blind Method; Female; Flumazenil; Follicular Phase; GABA Modulators; gamma-Aminobutyri | 2004 |
Effects of the benzodiazepine antagonist flumazenil in PTSD.
Topics: Anxiety Disorders; Arousal; Combat Disorders; Double-Blind Method; Flumazenil; GABA Modulators; GABA | 1995 |
Effects of flumazenil on cholecystokinin-tetrapeptide-induced panic symptoms in healthy volunteers.
Topics: Adult; Amino Acid Sequence; Cross-Over Studies; Double-Blind Method; Female; Flumazenil; GABA-A Rece | 1994 |
Effect of flumazenil in lactate-sensitive patients with panic disorder.
Topics: Adrenocorticotropic Hormone; Adult; Double-Blind Method; Female; Flumazenil; Heart Rate; Humans; Hyd | 1998 |
Acute effects of low-dose flumazenil in panic disorder.
Topics: Adult; Dose-Response Relationship, Drug; Fear; Female; Flumazenil; GABA Modulators; Heart Rate; Huma | 1998 |
Stressful reactions and panic attacks induced by flumazenil in chronic benzodiazepine users.
Topics: Adult; Anti-Anxiety Agents; Arousal; Diazepam; Double-Blind Method; Female; Flumazenil; GABA Modulat | 1998 |
Behavioral, neuroendocrine, and cardiovascular response to flumazenil: no evidence for an altered benzodiazepine receptor sensitivity in panic disorder.
Topics: Adrenocorticotropic Hormone; Adult; Affective Symptoms; Analysis of Variance; Arousal; Behavioral Sy | 1999 |
Flumazenil challenge in social phobia.
Topics: Adult; Anxiety; Benzodiazepines; Blood Pressure; Case-Control Studies; Cross-Over Studies; Double-Bl | 2000 |
Response to flumazenil in women with premenstrual dysphoric disorder.
Topics: Cross-Over Studies; Double-Blind Method; Female; Flumazenil; GABA Modulators; Humans; Luteal Phase; | 2000 |
Does 5-HT restrain panic? A tryptophan depletion study in panic disorder patients recovered on paroxetine.
Topics: Adult; Affect; Aged; Agoraphobia; Cross-Over Studies; Double-Blind Method; Female; Flumazenil; GABA | 2002 |
8 other studies available for flumazenil and Panic Attacks
| Article | Year |
|---|---|
Altered cerebral gamma-aminobutyric acid type A-benzodiazepine receptor binding in panic disorder determined by [11C]flumazenil positron emission tomography.
Topics: Adult; Brain; Brain Mapping; Carbon Radioisotopes; Cerebral Cortex; Comorbidity; Depressive Disorder | 2008 |
Panic attack associated with flumazenil at electroconvulsive therapy session.
Topics: Electroconvulsive Therapy; Female; Flumazenil; GABA Modulators; Humans; Middle Aged; Panic Disorder; | 2009 |
Reduced gamma-aminobutyric acid(A)-benzodiazepine binding sites in insular cortex of individuals with panic disorder.
Topics: Adult; Binding Sites; Brain; Carbon Radioisotopes; Cerebral Cortex; Comorbidity; Depressive Disorder | 2007 |
Abnormal regional benzodiazepine receptor uptake in the prefrontal cortex in patients with panic disorder.
Topics: Female; Flumazenil; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Panic Disorder; | 1995 |
Decreased benzodiazepine receptor binding in panic disorder measured by IOMAZENIL-SPECT. A preliminary report.
Topics: Adult; Cerebral Ventricles; Female; Flumazenil; Frontal Lobe; Humans; Male; Occipital Lobe; Panic Di | 1994 |
Decreased brain GABA(A)-benzodiazepine receptor binding in panic disorder: preliminary results from a quantitative PET study.
Topics: Adult; Aged; Brain; Carbon Radioisotopes; Cerebral Cortex; Female; Flumazenil; Functional Laterality | 1998 |
Behavioral, neuroendocrine, and cardiovascular response to flumazenil: no evidence for an altered benzodiazepine receptor sensitivity in panic disorder.
Topics: Confounding Factors, Epidemiologic; Flumazenil; GABA Modulators; Hemodynamics; Humans; Panic Disorde | 1999 |
SPECT [I-123]iomazenil measurement of the benzodiazepine receptor in panic disorder.
Topics: Adolescent; Adult; Aged; Female; Flumazenil; GABA Modulators; Hippocampus; Humans; Iodine Radioisoto | 2000 |