Page last updated: 2024-10-27

flumazenil and Neuralgia

flumazenil has been researched along with Neuralgia in 4 studies

Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.

Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.

Research Excerpts

ExcerptRelevanceReference
"It is associated with allodynia and hyperalgesia."1.48Neurobiological mechanisms of antiallodynic effect of transcranial direct current stimulation (tDCS) in a mice model of neuropathic pain. ( Caumo, W; Dos Santos, ARS; Martins, DF; Martins, TC; Medeiros, LF; Nucci-Martins, C; Siteneski, A; Souza, A; Torres, ILS, 2018)
"The effects of diazepam or Ro5-4864 on neuropathic pain were completely blocked by pretreatment with a neurosteroid synthesis inhibitor, aminoglutethimide (AMG)."1.43Inhibition of Neuropathic Pain by a Single Intraperitoneal Injection of Diazepam in the Rat: Possible Role of Neurosteroids. ( Chen, SL; Liu, XG; Wei, XH; Zang, Y; Zheng, WH, 2016)
"At doses producing already maximal antihyperalgesia, HZ166 was devoid of sedation and motor impairment, and showed no loss of analgesic activity during a 9-day chronic treatment period (i."1.37HZ166, a novel GABAA receptor subtype-selective benzodiazepine site ligand, is antihyperalgesic in mouse models of inflammatory and neuropathic pain. ( Benke, D; Besson, M; Cook, JM; Daali, Y; Desmeules, J; Di Lio, A; Edwankar, R; Wang, ZJ; Zeilhofer, HU, 2011)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Souza, A1
Martins, DF1
Medeiros, LF1
Nucci-Martins, C1
Martins, TC1
Siteneski, A1
Caumo, W1
Dos Santos, ARS1
Torres, ILS1
Chen, SL1
Zang, Y1
Zheng, WH1
Wei, XH1
Liu, XG1
Di Lio, A1
Benke, D1
Besson, M1
Desmeules, J1
Daali, Y1
Wang, ZJ1
Edwankar, R1
Cook, JM1
Zeilhofer, HU1
Orliaguet, G1
Nguyen, JP1
Abay, K1
Berberich, E1
Melon, E1
Duvaldestin, P1

Other Studies

4 other studies available for flumazenil and Neuralgia

ArticleYear
Neurobiological mechanisms of antiallodynic effect of transcranial direct current stimulation (tDCS) in a mice model of neuropathic pain.
    Brain research, 2018, 03-01, Volume: 1682

    Topics: Adenosine A1 Receptor Antagonists; Animals; Caffeine; Central Nervous System Stimulants; Disease Mod

2018
Inhibition of Neuropathic Pain by a Single Intraperitoneal Injection of Diazepam in the Rat: Possible Role of Neurosteroids.
    The Chinese journal of physiology, 2016, 02-29, Volume: 59, Issue:1

    Topics: Animals; Benzodiazepinones; Carrier Proteins; Diazepam; Flumazenil; Injections, Intraperitoneal; Int

2016
HZ166, a novel GABAA receptor subtype-selective benzodiazepine site ligand, is antihyperalgesic in mouse models of inflammatory and neuropathic pain.
    Neuropharmacology, 2011, Volume: 60, Issue:4

    Topics: Animals; Benzodiazepines; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; GABA-A Rece

2011
[Anesthesia for thalamic stimulations: value of flumazenil].
    Annales francaises d'anesthesie et de reanimation, 1991, Volume: 10, Issue:3

    Topics: Adult; Aged; Anesthesia, General; Electric Stimulation; Flumazenil; Humans; Intraoperative Period; M

1991