Page last updated: 2024-10-27

flumazenil and Myasthenic Syndromes, Congenital

flumazenil has been researched along with Myasthenic Syndromes, Congenital in 3 studies

Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.

Myasthenic Syndromes, Congenital: A heterogeneous group of disorders characterized by a congenital defect in neuromuscular transmission at the NEUROMUSCULAR JUNCTION. This includes presynaptic, synaptic, and postsynaptic disorders (that are not of autoimmune origin). The majority of these diseases are caused by mutations of various subunits of the nicotinic acetylcholine receptor (RECEPTORS, NICOTINIC) on the postsynaptic surface of the junction. (From Arch Neurol 1999 Feb;56(2):163-7)

Research Excerpts

ExcerptRelevanceReference
"Mutations in its gene may cause congenital myasthenic syndromes."1.30A common mutation (epsilon1267delG) in congenital myasthenic patients of Gypsy ethnic origin. ( Abicht, A; Brunner, J; Herczegfalvi, A; Horváth, R; Janssen, G; Jost, W; Karcagi, V; Lochmüller, H; Mortier, W; Müller-Felber, W; Pongratz, D; Ramaekers, V; Rüdel, R; Schara, U; Schlotter, B; Seidel, U; Stucka, R, 1999)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Urtizberea, JA1
Lochmuller, H2
Tournev, I1
Natera-de Benito, D1
Domínguez-Carral, J1
Muelas, N1
Nascimento, A1
Ortez, C1
Jaijo, T1
Arteaga, R1
Colomer, J1
Vilchez, JJ1
Abicht, A1
Stucka, R1
Karcagi, V1
Herczegfalvi, A1
Horváth, R1
Mortier, W1
Schara, U1
Ramaekers, V1
Jost, W1
Brunner, J1
Janssen, G1
Seidel, U1
Schlotter, B1
Müller-Felber, W1
Pongratz, D1
Rüdel, R1

Other Studies

3 other studies available for flumazenil and Myasthenic Syndromes, Congenital

ArticleYear
[Myology and ethnic minorities: all roads lead to the Roma].
    Medecine sciences : M/S, 2015, Volume: 31 Spec No 3

    Topics: Bulgaria; Congresses as Topic; Consanguinity; Culture; Ethnicity; Founder Effect; France; History, 1

2015
Phenotypic heterogeneity in two large Roma families with a congenital myasthenic syndrome due to CHRNE 1267delG mutation. A long-term follow-up.
    Neuromuscular disorders : NMD, 2016, Volume: 26, Issue:11

    Topics: Adolescent; Adult; Child; Family; Female; Follow-Up Studies; Humans; Male; Middle Aged; Mutation; My

2016
A common mutation (epsilon1267delG) in congenital myasthenic patients of Gypsy ethnic origin.
    Neurology, 1999, Oct-22, Volume: 53, Issue:7

    Topics: Adolescent; Adult; Child; Child, Preschool; Europe; Female; Genotype; Homozygote; Humans; Infant; Ma

1999