flumazenil has been researched along with Mental Disorders in 18 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Flumazenil was efficient for leading out from coma in 86% of cases with poisoning only by benzodiazepines and 13% of cases with mixed intoxications mainly containing benzodiazepines and alcohol or carbamazepine." | 3.69 | [Suicidal poisoning with benzodiazepines]. ( Chodorowski, Z; Sein Anand, J, 1997) |
| "Flumazenil is a benzodiazepine receptor antagonist." | 2.39 | The effects of flumazenil in neuropsychiatric disorders. ( Malizia, AL; Nutt, DJ, 1995) |
| "Withdrawal symptoms were tracked, however, the nature and severity of these symptoms differed between patients." | 1.35 | The role of flumazenil in the treatment of benzodiazepine dependence: physiological and psychological profiles. ( Hood, S; Hulse, G; O'Neil, G, 2009) |
| "The purpose of this study is visual evaluation of the distribution of I-123 iomazenil in the brains of patients with various types of mental disorder and to examine whether chronic administration of a clinical dose of benzodiazepine (BZ) affects the binding of I-123 iomazenil to BZ receptors (BZR)." | 1.30 | I-123 iomazenil SPECT in patients with mental disorders. ( Nakabeppu, Y; Nakajo, M; Naruo, T; Nozoe, S; Obo, Y; Takigawa, M; Tanaka, H; Tani, A; Tsuchimochi, S, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (22.22) | 18.7374 |
| 1990's | 9 (50.00) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andersson, JD | 1 |
| Matuskey, D | 1 |
| Finnema, SJ | 1 |
| Hood, S | 1 |
| O'Neil, G | 1 |
| Hulse, G | 1 |
| Torizuka, K | 3 |
| Uemura, K | 3 |
| Toru, M | 1 |
| Shinohara, Y | 1 |
| Nishimura, T | 1 |
| Yonekura, Y | 3 |
| Nakagawara, J | 3 |
| Matsuda, H | 1 |
| Sakai, F | 1 |
| Matsuda, K | 3 |
| Fukuyama, H | 3 |
| Morimoto, K | 3 |
| Malizia, AL | 1 |
| Nutt, DJ | 1 |
| Tohru, M | 1 |
| Thoru, M | 1 |
| Thakker, P | 1 |
| Gallagher, TM | 1 |
| Jones, EA | 1 |
| Weissenborn, K | 1 |
| Chodorowski, Z | 1 |
| Sein Anand, J | 1 |
| Nakabeppu, Y | 1 |
| Nakajo, M | 1 |
| Naruo, T | 1 |
| Obo, Y | 1 |
| Nozoe, S | 1 |
| Takigawa, M | 1 |
| Tsuchimochi, S | 1 |
| Tani, A | 1 |
| Tanaka, H | 1 |
| Cooper, MR | 1 |
| Leykin, Y | 1 |
| Halpern, P | 1 |
| Silbiger, A | 1 |
| Sorkin, P | 1 |
| Niv, D | 1 |
| Rudick, V | 1 |
| Geller, E | 1 |
| Persson, A | 1 |
| Ehrin, E | 1 |
| Eriksson, L | 1 |
| Farde, L | 1 |
| Hedström, CG | 1 |
| Litton, JE | 1 |
| Mindus, P | 1 |
| Sedvall, G | 1 |
| López, JA | 1 |
| García, RF | 1 |
| Martí, TS | 1 |
| Fehér, Á | 1 |
| Juhász, A | 1 |
| Rimanóczy, Á | 1 |
| Álmos, P | 1 |
| Béres, J | 1 |
| Janka, Z | 1 |
| Kálmán, J | 1 |
| Olivan, G | 1 |
| Okruhlica, L | 1 |
| Medvecká, E | 1 |
| Medvecký, J | 1 |
3 reviews available for flumazenil and Mental Disorders
| Article | Year |
|---|---|
Positron emission tomography imaging of the γ-aminobutyric acid system.
Topics: Animals; Benzodiazepines; Brain; Carbon Radioisotopes; Flumazenil; Fluorine Radioisotopes; gamma-Ami | 2019 |
The effects of flumazenil in neuropsychiatric disorders.
Topics: Animals; Antidotes; Flumazenil; GABA Modulators; Humans; Mental Disorders | 1995 |
Neurology and the liver.
Topics: Ammonia; Brain Edema; Cholestasis; Diagnosis, Differential; Fatigue; Flumazenil; GABA Modulators; He | 1997 |
3 trials available for flumazenil and Mental Disorders
| Article | Year |
|---|---|
[A phase 3 clinical trial of 123I-iomazenil, a new central-type benzodiazepine receptor imaging agent (Part 2)--Report on clinical usefulness in diagnosis of degenerative neurological diseases and mental disorders].
Topics: Adult; Aged; Brain; Female; Flumazenil; GABA-A Receptor Agonists; Humans; Iodine Radioisotopes; Japa | 1996 |
[Phase 2 clinical study of 123I-iomazenil in various cerebral diseases: part 1--examination of injection dose and clinical indications].
Topics: Adult; Brain Diseases; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Mental Disorders; Mid | 1996 |
[Phase 2 clinical study of 123I-iomazenil in various cerebral diseases: part 2--clinical evaluation of central-type benzodiazepine receptor imaging with 123I-iomazenil SPECT].
Topics: Adult; Brain Diseases; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Mental Disorders; Mid | 1996 |
12 other studies available for flumazenil and Mental Disorders
| Article | Year |
|---|---|
The role of flumazenil in the treatment of benzodiazepine dependence: physiological and psychological profiles.
Topics: Adult; Benzodiazepines; Blood Pressure; Cohort Studies; Diagnosis, Dual (Psychiatry); Female; Flumaz | 2009 |
Flumazenil reverses paradoxical reaction to midazolam in a child.
Topics: Antidotes; Child; Flumazenil; Humans; Hypnotics and Sedatives; Male; Mental Disorders; Midazolam | 1996 |
[Suicidal poisoning with benzodiazepines].
Topics: Adolescent; Adult; Aged; Alcoholism; Benzodiazepines; Carbamazepine; Coma; Ethanol; Female; Flumazen | 1997 |
I-123 iomazenil SPECT in patients with mental disorders.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Brain; Female; Flumazenil; Humans; Iodine Radioisotop | 1997 |
Re: I-123 iomazenil SPECT in patients with mental disorders.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Brain; Female; Flumazenil; Humans; Iodine Radioisotop | 1999 |
Acute poisoning treated in the intensive care unit: a case series.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Critical Care; Female; Flumazenil; Humans | 1989 |
Imaging of [11C]-labelled Ro 15-1788 binding to benzodiazepine receptors in the human brain by positron emission tomography.
Topics: Adult; Animals; Benzodiazepinones; Brain; Cerebral Cortex; Diazepam; Flumazenil; Humans; Kinetics; M | 1985 |
Drugs and Mental Health Problems among the Roma: Protective Factors Promoted by the Iglesia Evangélica Filadelfia.
Topics: Adult; Female; Health Promotion; Humans; Male; Mental Disorders; Middle Aged; Protective Factors; Pr | 2018 |
Dopamine metabolism-related gene polymorphisms in Roma (Gypsy) and Hungarian populations.
Topics: Adult; Alleles; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Genotype; Humans; Hun | 2011 |
The health status of delinquent gipsy youths in Spain.
Topics: Adolescent; Disease; Female; Health Status; Humans; Juvenile Delinquency; Male; Mental Disorders; Nu | 2002 |
[Psychiatric disorders in the gypsy ethnic group].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Czechoslovakia; Ethnicity; Female; Humans; Male; | 1987 |
[Characteristics of psychopathologic manifestations in gypsies].
Topics: Czechoslovakia; Ethnicity; Humans; Mental Disorders; Roma | 1986 |