Page last updated: 2024-10-27

flumazenil and MS (Multiple Sclerosis)

flumazenil has been researched along with MS (Multiple Sclerosis) in 8 studies

Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.

Research Excerpts

ExcerptRelevanceReference
"Using positron emission tomography (PET) with [(11) C]flumazenil ([(11) C]FMZ), an antagonist of the central benzodiazepine site located within the GABAA receptor, we quantified and mapped neuronal damage in the gray matter (GM) of patients with multiple sclerosis (MS) at distinct disease stages."7.81The neuronal component of gray matter damage in multiple sclerosis: A [(11) C]flumazenil positron emission tomography study. ( Assouad, R; Bodini, B; Bottin, L; Bottlaender, M; Dollé, F; Freeman, L; Garcia-Lorenzo, D; Granger, B; Leroy, C; Louapre, C; Lubetzki, C; Papeix, C; Stankoff, B; Tourbah, A, 2015)
"Using positron emission tomography (PET) with [(11) C]flumazenil ([(11) C]FMZ), an antagonist of the central benzodiazepine site located within the GABAA receptor, we quantified and mapped neuronal damage in the gray matter (GM) of patients with multiple sclerosis (MS) at distinct disease stages."3.81The neuronal component of gray matter damage in multiple sclerosis: A [(11) C]flumazenil positron emission tomography study. ( Assouad, R; Bodini, B; Bottin, L; Bottlaender, M; Dollé, F; Freeman, L; Garcia-Lorenzo, D; Granger, B; Leroy, C; Louapre, C; Lubetzki, C; Papeix, C; Stankoff, B; Tourbah, A, 2015)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's3 (37.50)18.2507
2000's1 (12.50)29.6817
2010's1 (12.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Kang, Y1
Rúa, SMH1
Kaunzner, UW1
Perumal, J1
Nealon, N1
Qu, W1
Kothari, PJ1
Vartanian, T1
Kuceyeski, A1
Gauthier, SA1
Freeman, L1
Garcia-Lorenzo, D1
Bottin, L1
Leroy, C1
Louapre, C1
Bodini, B1
Papeix, C1
Assouad, R1
Granger, B1
Tourbah, A1
Dollé, F1
Lubetzki, C1
Bottlaender, M1
Stankoff, B1
Fernández, O1
Fernández, V1
Martinez-Cabrera, V1
Mayorga, C1
Alonso, A1
León, A1
Arnal, C1
Hens, M1
Luque, G1
de Ramón, E1
Caballero, A1
Leyva, L1
Gyódi, E4
Benczur, M1
Pálffy, G3
Tálas, M1
Petrányi, G3
Földes, I1
Hollán, SR1
Milanov, I1
Topalov, N1
Kmetski, T1
Kálmán, B2
Takács, K2
Kramer, J1
Füst, G1
Tauszik, T2
Guseo, A2
Kuntár, L2
Komoly, S1
Nagy, C2

Other Studies

8 other studies available for flumazenil and MS (Multiple Sclerosis)

ArticleYear
A Multi-Ligand Imaging Study Exploring GABAergic Receptor Expression and Inflammation in Multiple Sclerosis.
    Molecular imaging and biology, 2020, Volume: 22, Issue:6

    Topics: Adult; Case-Control Studies; Cohort Studies; Female; Flumazenil; Gray Matter; Humans; Immunity, Inna

2020
The neuronal component of gray matter damage in multiple sclerosis: A [(11) C]flumazenil positron emission tomography study.
    Annals of neurology, 2015, Volume: 78, Issue:4

    Topics: Adult; Carbon Radioisotopes; Female; Flumazenil; Gray Matter; Humans; Male; Middle Aged; Multiple Sc

2015
Multiple sclerosis in Gypsies from southern Spain: prevalence, mitochondrial DNA haplogroups and HLA class II association.
    Tissue antigens, 2008, Volume: 71, Issue:5

    Topics: Adolescent; Adult; Aged; Alleles; DNA, Mitochondrial; Female; Genes, MHC Class II; Genetic Predispos

2008
Association between HLA B7, DR2 and dysfunction of natural- and antibody-mediated cytotoxicity without connection with the deficient interferon production in multiple sclerosis.
    Human immunology, 1982, Volume: 4, Issue:3

    Topics: Adult; Antibody-Dependent Cell Cytotoxicity; Cytotoxicity, Immunologic; Female; Genes, MHC Class II;

1982
Prevalence of multiple sclerosis in Gypsies and Bulgarians.
    Neuroepidemiology, 1999, Volume: 18, Issue:4

    Topics: Adolescent; Adult; Aged; Bulgaria; Child; Child, Preschool; Epidemiologic Methods; Female; Humans; I

1999
Sclerosis multiplex in gypsies.
    Acta neurologica Scandinavica, 1991, Volume: 84, Issue:3

    Topics: Alleles; Complement C4a; Complement C4b; Female; HLA-B Antigens; HLA-B7 Antigen; HLA-DQ Antigens; HL

1991
Association between the lack of HLA-DQw6 and the low incidence of multiple sclerosis in Hungarian Gypsies.
    Immunogenetics, 1990, Volume: 31, Issue:5-6

    Topics: Ethnicity; HLA-DQ Antigens; Humans; Hungary; Multiple Sclerosis; Polymorphism, Restriction Fragment

1990
Multiple sclerosis in 3 gipsy and 2 partly gipsy subjects (a clinical and immunogenetic study).
    Acta medica Hungarica, 1986, Volume: 43, Issue:1

    Topics: Adult; Ethnicity; Female; HLA Antigens; Humans; Hungary; Male; Middle Aged; Multiple Sclerosis; Roma

1986