flumazenil has been researched along with Liver Failure, Acute in 2 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The treatment with flumazenil completely abolished the decrease in the metabolite (P < 0." | 5.33 | Flumazenil-induced improvement of the central dopaminergic system in rats with acute hepatic failure. ( Adachi, N; Arai, T; Liu, K; Yano, M, 2005) |
| "The treatment with flumazenil completely abolished the decrease in the metabolite (P < 0." | 1.33 | Flumazenil-induced improvement of the central dopaminergic system in rats with acute hepatic failure. ( Adachi, N; Arai, T; Liu, K; Yano, M, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Quero Guillén, JC | 1 |
| Carmona Soria, I | 1 |
| García Montes, JM | 1 |
| Jiménez Sáenz, M | 1 |
| Herrerías Gutiérrez, JM | 1 |
| Yano, M | 1 |
| Adachi, N | 1 |
| Liu, K | 1 |
| Arai, T | 1 |
2 other studies available for flumazenil and Liver Failure, Acute
| Article | Year |
|---|---|
Hepatic encephalopathy: nomenclature, pathogenesis and treatment.
Topics: Anti-Bacterial Agents; Antifungal Agents; Bromocriptine; Dipeptides; Dopamine Agonists; Electroencep | 2003 |
Flumazenil-induced improvement of the central dopaminergic system in rats with acute hepatic failure.
Topics: Ammonia; Anesthesia; Animals; Biogenic Monoamines; Brain Chemistry; Central Nervous System; Dopamine | 2005 |