flumazenil has been researched along with Liver Diseases in 6 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Liver Diseases: Pathological processes of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the two patients, nordazepam accumulation (main active metabolite of clorazepam) was demonstrated as the cause of the coma." | 3.70 | Prolonged sedation requiring mechanical ventilation and continuous flumazenil infusion after routine doses of clorazepam for alcohol withdrawal syndrome. ( Alzieu, M; Becquemont, L; Delhotal Landes, B; Guglielminotti, J; Guidet, B; Maury, E; Offenstadt, G, 1999) |
| ")], a short half-life (45." | 1.28 | Pharmacokinetics of benzodiazepine antagonist Ro 15-1788 in cirrhotic patients with moderate or severe liver dysfunction. ( Butterworth, RF; Giguère, JF; Lavoie, J; Pomier-Layrargues, G; Willems, B, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wettstein, M | 1 |
| Häussinger, D | 1 |
| Guglielminotti, J | 1 |
| Maury, E | 1 |
| Alzieu, M | 1 |
| Delhotal Landes, B | 1 |
| Becquemont, L | 1 |
| Guidet, B | 1 |
| Offenstadt, G | 1 |
| Koczorek, M | 1 |
| van der Rijt, CC | 1 |
| Drost, RH | 1 |
| Schalm, SW | 1 |
| Schramel, M | 1 |
| Pomier-Layrargues, G | 1 |
| Giguère, JF | 1 |
| Lavoie, J | 1 |
| Willems, B | 1 |
| Butterworth, RF | 1 |
| Cruz, M | 1 |
| Dieguez, A | 1 |
| Fos, E | 1 |
| Hierro, F | 1 |
1 review available for flumazenil and Liver Diseases
| Article | Year |
|---|---|
[Hepatic encephalopathy--therapy].
Topics: Administration, Oral; Ammonia; Anti-Bacterial Agents; Diet, Protein-Restricted; Dipeptides; Flumazen | 2003 |
5 other studies available for flumazenil and Liver Diseases
| Article | Year |
|---|---|
Prolonged sedation requiring mechanical ventilation and continuous flumazenil infusion after routine doses of clorazepam for alcohol withdrawal syndrome.
Topics: Aged; Alcohol Withdrawal Seizures; Anticonvulsants; Antidotes; Bronchitis; Clorazepate Dipotassium; | 1999 |
[Chronic liver diseases. The nihilism has gone].
Topics: Amantadine; Antioxidants; Antiviral Agents; Chronic Disease; Dipeptides; Drug Therapy, Combination; | 2001 |
Pharmacokinetics of flumazenil in fulminant hepatic failure.
Topics: Adolescent; Chronic Disease; Female; Flumazenil; Humans; Liver Diseases; Male | 1991 |
Pharmacokinetics of benzodiazepine antagonist Ro 15-1788 in cirrhotic patients with moderate or severe liver dysfunction.
Topics: Adult; Blood Proteins; Female; Flumazenil; Half-Life; Humans; Infusions, Intravenous; Liver; Liver D | 1989 |
Epidemiologic survey on hepatitis B in Gypsy women.
Topics: Ethnicity; Female; Hepatitis B; Hepatitis B Surface Antigens; Humans; Liver Diseases; Pregnancy; Ris | 1988 |