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flumazenil and Liver Cirrhosis, Alcoholic

flumazenil has been researched along with Liver Cirrhosis, Alcoholic in 6 studies

Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.

Liver Cirrhosis, Alcoholic: FIBROSIS of the hepatic parenchyma due to chronic excess ALCOHOL DRINKING.

Research Excerpts

ExcerptRelevanceReference
"In animal studies as well as in a few cases in humans, the benzodiazepine antagonist flumazenil has been shown to reverse hepatic encephalopathy."7.68[Treatment of acute hepatic encephalopathy with flumazenil]. ( Bassoul, B; de La Coussaye, JE; Eledjam, JJ; Saissi, G; Viel, E, 1990)
"In animal studies as well as in a few cases in humans, the benzodiazepine antagonist flumazenil has been shown to reverse hepatic encephalopathy."3.68[Treatment of acute hepatic encephalopathy with flumazenil]. ( Bassoul, B; de La Coussaye, JE; Eledjam, JJ; Saissi, G; Viel, E, 1990)
" Consequently, it could be anticipated that hepatic disease affects the elimination and oral bioavailability of flumazenil."2.66Flumazenil disposition and elimination in cirrhosis. ( Janssen, U; Klotz, U; Maier, K; von Gaisberg, U; Walker, S, 1989)
"He was treated for hepatic encephalopathy with complete recovery and resolution of the neurologic findings."2.46Reversible hepatic decerebration: a case report and review of the literature. ( Antoun, SA; Delgado, F; Saad, D; Ta, H; Wehbe, E, 2010)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wehbe, E1
Saad, D1
Delgado, F1
Ta, H1
Antoun, SA1
Kapczinski, F2
Sherman, D1
Williams, R1
Lader, M1
Curran, V1
Amaral, OB1
Quevedo, J1
Walz, R1
Viel, E1
de La Coussaye, JE1
Bassoul, B1
Saissi, G1
Eledjam, JJ1
Janssen, U1
Walker, S2
Maier, K1
von Gaisberg, U1
Klotz, U2

Reviews

1 review available for flumazenil and Liver Cirrhosis, Alcoholic

ArticleYear
Reversible hepatic decerebration: a case report and review of the literature.
    European journal of gastroenterology & hepatology, 2010, Volume: 22, Issue:6

    Topics: Alcoholism; Decerebrate State; Flumazenil; Hepatic Encephalopathy; Humans; Liver Cirrhosis, Alcoholi

2010

Trials

3 trials available for flumazenil and Liver Cirrhosis, Alcoholic

ArticleYear
Differential effects of flumazenil in alcoholic and nonalcoholic cirrhotic patients.
    Psychopharmacology, 1995, Volume: 120, Issue:2

    Topics: Adult; Anxiety; Female; Flumazenil; Humans; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Liver Funct

1995
Flumazenil disposition and elimination in cirrhosis.
    Clinical pharmacology and therapeutics, 1989, Volume: 46, Issue:3

    Topics: Administration, Oral; Adult; Biological Availability; Chemical Phenomena; Chemistry; Clinical Trials

1989
Flumazenil and hepatic encephalopathy.
    Lancet (London, England), 1989, Jan-21, Volume: 1, Issue:8630

    Topics: Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Flumazenil; Hepatic Encephalopathy;

1989

Other Studies

2 other studies available for flumazenil and Liver Cirrhosis, Alcoholic

ArticleYear
Flumazenil and hepatic encephalopathy.
    Hepatology (Baltimore, Md.), 1999, Volume: 29, Issue:4

    Topics: Benzodiazepines; Flumazenil; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Liver Cirrhosis, Alcoh

1999
[Treatment of acute hepatic encephalopathy with flumazenil].
    Annales francaises d'anesthesie et de reanimation, 1990, Volume: 9, Issue:4

    Topics: Acute Disease; Flumazenil; Glasgow Coma Scale; Hepatic Encephalopathy; Humans; Liver Cirrhosis, Alco

1990