flumazenil has been researched along with Inflammation in 14 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
Excerpt | Relevance | Reference |
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"The mechanism underlying the previous findings that the development of antinociceptive tolerance to morphine was significantly delayed in the presence of inflammatory pain induced by formalin was examined." | 7.69 | Involvement of pain associated anxiety in the development of morphine tolerance in formalin treated mice. ( Kaneto, H; Rahman, AF; Takahashi, M, 1994) |
"The mechanism underlying the previous findings that the development of antinociceptive tolerance to morphine was significantly delayed in the presence of inflammatory pain induced by formalin was examined." | 3.69 | Involvement of pain associated anxiety in the development of morphine tolerance in formalin treated mice. ( Kaneto, H; Rahman, AF; Takahashi, M, 1994) |
"Ischemic stroke is caused by interruption or significant impairment of blood supply to the brain, which leads to a cascade of metabolic and molecular alterations resulting in functional disturbance and morphologic damage." | 2.50 | Radionuclide imaging in ischemic stroke. ( Heiss, WD, 2014) |
"NAFLD is the liver manifestation of metabolic syndrome (MS)." | 1.40 | Gamma-glutamyl transpeptidase level associated with metabolic syndrome and proinflammatory parameters in the young Roma population in eastern Slovakia: a population-based study. ( Drazilová, S; Fedacko, J; Gecková, AM; Janicko, M; Jarcuska, P; Kristian, P; Mareková, M; Pella, D; Senajová, G; Siegfried, L; Tkác, M; Veselíny, E, 2014) |
"Obesity-induced metabolic syndrome is a multiple risk factor for cardiovascular (CV) risk factors and type 2 diabetes, and ethnic minorities seem to have unfavourable medical risk factors in general more frequently than majority populations." | 1.40 | Prevalence of cardiovascular risk factors in relation to metabolic syndrome in the Roma population compared with the non-Roma population in the eastern part of Slovakia. ( Babcák, M; Babinská, I; Cecetková, B; Drazilová, S; Fedacko, J; Gecková, AM; Janicko, M; Jankajová, M; Jarcuska, P; Kalanin, P; Kmec, J; Mareková, M; Pazinka, P; Pella, D; Pella, J; Sabol, F; Siegfried, L; Veselíny, E, 2014) |
"At doses producing already maximal antihyperalgesia, HZ166 was devoid of sedation and motor impairment, and showed no loss of analgesic activity during a 9-day chronic treatment period (i." | 1.37 | HZ166, a novel GABAA receptor subtype-selective benzodiazepine site ligand, is antihyperalgesic in mouse models of inflammatory and neuropathic pain. ( Benke, D; Besson, M; Cook, JM; Daali, Y; Desmeules, J; Di Lio, A; Edwankar, R; Wang, ZJ; Zeilhofer, HU, 2011) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (7.14) | 18.2507 |
2000's | 3 (21.43) | 29.6817 |
2010's | 7 (50.00) | 24.3611 |
2020's | 3 (21.43) | 2.80 |
Authors | Studies |
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Saunders, MJ | 1 |
Edwards, BS | 1 |
Zhu, J | 1 |
Sklar, LA | 1 |
Graves, SW | 1 |
Ji, MH | 1 |
Zhang, L | 1 |
Mao, MJ | 1 |
Zhang, H | 1 |
Yang, JJ | 1 |
Qiu, LL | 1 |
Kang, Y | 1 |
Rúa, SMH | 1 |
Kaunzner, UW | 1 |
Perumal, J | 1 |
Nealon, N | 1 |
Qu, W | 1 |
Kothari, PJ | 1 |
Vartanian, T | 1 |
Kuceyeski, A | 1 |
Gauthier, SA | 1 |
Matsumoto, D | 1 |
Ushio, S | 1 |
Wada, Y | 1 |
Noda, Y | 1 |
Esumi, S | 1 |
Izushi, Y | 1 |
Kitamura, Y | 1 |
Sendo, T | 1 |
Parente, A | 1 |
Vállez García, D | 1 |
Shoji, A | 1 |
Lopes Alves, I | 1 |
Maas, B | 1 |
Zijlma, R | 1 |
Dierckx, RA | 1 |
Buchpiguel, CA | 1 |
de Vries, EF | 1 |
Doorduin, J | 1 |
Heiss, WD | 2 |
Di Lio, A | 1 |
Benke, D | 1 |
Besson, M | 1 |
Desmeules, J | 1 |
Daali, Y | 1 |
Wang, ZJ | 1 |
Edwankar, R | 1 |
Cook, JM | 1 |
Zeilhofer, HU | 1 |
Romero Gómez, M | 1 |
Bautista, JD | 1 |
Grande, L | 1 |
Ramos Guerrero, RM | 1 |
Sánchez Muñoz, D | 1 |
Anseloni, VC | 1 |
Gold, MS | 1 |
Rahman, AF | 1 |
Takahashi, M | 1 |
Kaneto, H | 1 |
Mediratta, PK | 1 |
Sharma, KK | 1 |
Singh, S | 1 |
Jarcuska, P | 4 |
Janicko, M | 2 |
Drazilová, S | 2 |
Senajová, G | 1 |
Veselíny, E | 2 |
Fedacko, J | 2 |
Siegfried, L | 2 |
Kristian, P | 1 |
Tkác, M | 1 |
Pella, D | 2 |
Mareková, M | 2 |
Gecková, AM | 2 |
Pella, J | 1 |
Sabol, F | 1 |
Pazinka, P | 1 |
Jankajová, M | 1 |
Kmec, J | 1 |
Babcák, M | 1 |
Kalanin, P | 1 |
Babinská, I | 1 |
Cecetková, B | 1 |
3 reviews available for flumazenil and Inflammation
Article | Year |
---|---|
Radionuclide imaging in ischemic stroke.
Topics: Animals; Brain; Brain Ischemia; Carbon Radioisotopes; Cerebrovascular Disorders; Flumazenil; Humans; | 2014 |
The ischemic penumbra: how does tissue injury evolve?
Topics: Animals; Brain; Brain Edema; Brain Ischemia; Cats; Cerebral Infarction; Cerebrovascular Circulation; | 2012 |
[New concepts in the physiopathology of hepatic encephalopathy and therapeutic prospects].
Topics: Ammonia; Brain; Brain Edema; Dipeptides; Flumazenil; Glutaminase; Glutamine; Hepatic Encephalopathy; | 2004 |
11 other studies available for flumazenil and Inflammation
Article | Year |
---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Overinhibition mediated by parvalbumin interneurons might contribute to depression-like behavior and working memory impairment induced by lipopolysaccharide challenge.
Topics: Animals; Behavior, Animal; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; Fl | 2020 |
A Multi-Ligand Imaging Study Exploring GABAergic Receptor Expression and Inflammation in Multiple Sclerosis.
Topics: Adult; Case-Control Studies; Cohort Studies; Female; Flumazenil; Gray Matter; Humans; Immunity, Inna | 2020 |
Bumetanide prevents diazepam-modified anxiety-like behavior in lipopolysaccharide-treated mice.
Topics: Animals; Anti-Anxiety Agents; Anti-Bacterial Agents; Anxiety; Behavior, Animal; Bicuculline; Bumetan | 2021 |
Contribution of neuroinflammation to changes in [
Topics: Animals; Biological Transport; Carbon Radioisotopes; Flumazenil; Inflammation; Male; Pons; Positron- | 2017 |
HZ166, a novel GABAA receptor subtype-selective benzodiazepine site ligand, is antihyperalgesic in mouse models of inflammatory and neuropathic pain.
Topics: Animals; Benzodiazepines; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; GABA-A Rece | 2011 |
Inflammation-induced shift in the valence of spinal GABA-A receptor-mediated modulation of nociception in the adult rat.
Topics: Animals; Antineoplastic Agents; Flumazenil; Freund's Adjuvant; GABA Agonists; GABA Antagonists; GABA | 2008 |
Involvement of pain associated anxiety in the development of morphine tolerance in formalin treated mice.
Topics: Animals; Anxiety; Aspirin; Diazepam; Drug Tolerance; Flumazenil; Formaldehyde; Indomethacin; Inflamm | 1994 |
Evaluation of immunomodulatory potential of Ocimum sanctum seed oil and its possible mechanism of action.
Topics: Adjuvants, Immunologic; Animals; Antibody Formation; Diazepam; Erythrocytes; Flumazenil; Foot; GABA | 2002 |
Gamma-glutamyl transpeptidase level associated with metabolic syndrome and proinflammatory parameters in the young Roma population in eastern Slovakia: a population-based study.
Topics: Adolescent; Adult; C-Reactive Protein; Comorbidity; Cross-Sectional Studies; Diet; Fatty Liver; Fema | 2014 |
Prevalence of cardiovascular risk factors in relation to metabolic syndrome in the Roma population compared with the non-Roma population in the eastern part of Slovakia.
Topics: Adolescent; Adult; Age Distribution; Body Mass Index; Cardiovascular Diseases; Comorbidity; Dyslipid | 2014 |