flumazenil has been researched along with Inadequate Sleep in 12 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, we investigated the possible involvement of GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice." | 7.74 | Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice. ( Kumar, A; Singh, A, 2008) |
| " In the present study, we investigated the possible involvement of GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice." | 3.74 | Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice. ( Kumar, A; Singh, A, 2008) |
| "The antidepressive effect of sleep deprivation (SD) in depressed patients disappears after sleep of the recovery night and after early morning naps." | 2.73 | Effect of flumazenil-augmentation on microsleep and mood in depressed patients during partial sleep deprivation. ( Brand, S; Hatzinger, M; Hemmeter, U; Holsboer-Trachsler, E, 2007) |
| "Total sleep deprivation is the classic variant of its clinical use." | 2.44 | Sleep deprivation therapy. ( Svestka, J, 2008) |
| "Treatment with melatonin (5 and 10 mg/kg, ip) significantly improved locomotor activity, weight loss and antianxiety effect as compared to control (sleep deprived)." | 1.37 | Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behavior modification and oxidative damage in mice. ( Kumar, A; Kumar, P; Singh, A, 2011) |
| "Treatment with melatonin (5 mg/kg and 10 mg/kg, ip) significantly improved locomotor activity, weight loss and antianxiety effect as compared with control (sleep-deprived)." | 1.35 | Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behaviour modification and oxidative damage in mice. ( Kumar, A; Singh, A, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Svestka, J | 1 |
| Singh, A | 3 |
| Kumar, A | 3 |
| Kumar, P | 1 |
| Hemmeter, U | 2 |
| Hatzinger, M | 2 |
| Brand, S | 1 |
| Holsboer-Trachsler, E | 2 |
| Ohayon, MM | 1 |
| Emrich, HM | 2 |
| Sonderegger, P | 1 |
| Mai, N | 1 |
| Pokk, P | 2 |
| Zharkovsky, A | 1 |
| Seifritz, E | 1 |
| Trachsel, L | 1 |
| Lauer, CJ | 1 |
| Holsboer, F | 1 |
| Väli, M | 1 |
| Lavie, P | 2 |
| Peled, R | 1 |
| Wollman, M | 1 |
| Zomer, J | 1 |
| Tzischinsky, O | 1 |
1 review available for flumazenil and Inadequate Sleep
| Article | Year |
|---|---|
Sleep deprivation therapy.
Topics: Antipsychotic Agents; Circadian Rhythm; Clinical Trials as Topic; Combined Modality Therapy; Depress | 2008 |
4 trials available for flumazenil and Inadequate Sleep
| Article | Year |
|---|---|
Effect of flumazenil-augmentation on microsleep and mood in depressed patients during partial sleep deprivation.
Topics: Adult; Affect; Arousal; Attention; Combined Modality Therapy; Depressive Disorder, Major; Double-Bli | 2007 |
Action of the benzodiazepine antagonist Ro 15-1788 in humans after sleep withdrawal.
Topics: Adult; Arousal; Attention; Benzodiazepinones; Clinical Trials as Topic; Double-Blind Method; Flumaze | 1984 |
Effects of flumazenil on recovery sleep and hormonal secretion after sleep deprivation in male controls.
Topics: Adrenocorticotropic Hormone; Adult; Electroencephalography; Flumazenil; Growth Hormone; Humans; Hydr | 1995 |
RO 15-1788 decreases hypnotic effects of sleep deprivation.
Topics: Adult; Arousal; Benzodiazepines; Dose-Response Relationship, Drug; Emotions; Flumazenil; Humans; Hyp | 1987 |
7 other studies available for flumazenil and Inadequate Sleep
| Article | Year |
|---|---|
Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice.
Topics: Animals; Anxiety; Behavior, Animal; Body Weight; Catalase; Dose-Response Relationship, Drug; Flumaze | 2008 |
Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behaviour modification and oxidative damage in mice.
Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Body Weight; Dose-Response Relationship, Drug; Fem | 2009 |
Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behavior modification and oxidative damage in mice.
Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Flumazenil; GABA Modulators; gamma-Aminobutyric Ac | 2011 |
Insomnia: a ticking clock for depression?
Topics: Combined Modality Therapy; Comorbidity; Depressive Disorder; Flumazenil; GABA Modulators; GABA-A Rec | 2007 |
The effects of drugs acting at GABA-benzodiazepine-barbiturate receptor complex on the behaviour of sleep-deprived mice.
Topics: Analysis of Variance; Animals; Azides; Behavior, Animal; Benzodiazepines; Convulsants; Diazepam; Flu | 1995 |
The effects of flumazenil, Ro 154513 and beta-CCM on the behaviour of control and stressed mice in the staircase test.
Topics: Animals; Arousal; Azides; Benzodiazepines; Carbolines; Dose-Response Relationship, Drug; Escape Reac | 2001 |
Agonist-like effects of the benzodiazepine receptor antagonist RO 15-1788.
Topics: Adult; Arousal; Flumazenil; Humans; Male; Reaction Time; Receptors, GABA-A; Sleep Deprivation; Sleep | 1987 |