flumazenil has been researched along with Hyperphagia in 5 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Hyperphagia: Ingestion of a greater than optimal quantity of food.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Interestingly, benzodiazepine receptor antagonist flumazenil (5 ng/rat, icv), augmented the orexin-A (30 nM/rat, icv) induced hyperphagia; the effect may be attributed to the intrinsic activity of the agent." | 3.73 | GABA(A) receptors mediate orexin-A induced stimulation of food intake. ( Carta, A; Chopde, CT; Kokare, DM; Patole, AM; Subhedar, NK, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kokare, DM | 1 |
| Patole, AM | 1 |
| Carta, A | 1 |
| Chopde, CT | 1 |
| Subhedar, NK | 1 |
| Higgs, S | 2 |
| Cooper, SJ | 3 |
| Van Miert, AS | 1 |
| Koot, M | 1 |
| Van Duin, CT | 1 |
| Gilbert, DB | 1 |
5 other studies available for flumazenil and Hyperphagia
| Article | Year |
|---|---|
GABA(A) receptors mediate orexin-A induced stimulation of food intake.
Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Eating; Flumazenil; GABA Agonists; GABA Antagon | 2006 |
Increased food intake following injection of the benzodiazepine receptor agonist midazolam into the IVth ventricle.
Topics: Animals; Anti-Anxiety Agents; Cerebral Ventricles; Dose-Response Relationship, Drug; Eating; Flumaze | 1996 |
Hyperphagia induced by direct administration of midazolam into the parabrachial nucleus of the rat.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Behavior, Animal; Cerebral Ventricles; Feeding B | 1996 |
Appetite-modulating drugs in dwarf goats, with special emphasis on benzodiazepine-induced hyperphagia and its antagonism by flumazenil and RO 15-3505.
Topics: Animals; Anti-Anxiety Agents; Appetite Regulation; Azepines; Benzodiazepines; Benzodiazepinones; Bod | 1989 |
Clonazepam-induced hyperphagia in nondeprived rats: tests of pharmacological specificity with Ro5-4864, Ro5-3663, Ro15-1788 and CGS 9896.
Topics: Animals; Benzodiazepinones; Clonazepam; Drug Interactions; Feeding Behavior; Flumazenil; Humans; Hyp | 1985 |