flumazenil has been researched along with Hepatolenticular Degeneration in 2 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Hepatolenticular Degeneration: A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CORNEA; and other organs. It is caused by defects in the ATP7B gene encoding copper-transporting ATPase 2 (EC 3.6.3.4), also known as the Wilson disease protein. The overload of copper inevitably leads to progressive liver and neurological dysfunction such as LIVER CIRRHOSIS; TREMOR; ATAXIA and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, EA | 1 |
| Weissenborn, K | 1 |
| Todorov, T | 1 |
| Savov, A | 1 |
| Mihaylova, V | 1 |
| Buettner, J | 1 |
| Koseva, O | 1 |
| Krustev, Z | 1 |
| Jelev, H | 1 |
| Tournev, I | 1 |
| Penkov, V | 1 |
| Konstantinova, D | 1 |
| Tankova, L | 1 |
| Tzolova, N | 1 |
| Kremensky, I | 1 |
| Schmidt, H | 1 |
1 review available for flumazenil and Hepatolenticular Degeneration
| Article | Year |
|---|---|
Neurology and the liver.
Topics: Ammonia; Brain Edema; Cholestasis; Diagnosis, Differential; Fatigue; Flumazenil; GABA Modulators; He | 1997 |
1 other study available for flumazenil and Hepatolenticular Degeneration
| Article | Year |
|---|---|
Ethnic specific background of mutations in Bulgarian patients with Wilson disease.
Topics: Adolescent; Adult; Age of Onset; Alleles; Bulgaria; Ethnicity; Gene Expression; Haplotypes; Hepatole | 2007 |