flumazenil has been researched along with Glaucoma in 12 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (50.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morlino, S | 1 |
| Alesi, V | 1 |
| Calì, F | 1 |
| Lepri, FR | 1 |
| Secinaro, A | 1 |
| Grammatico, P | 1 |
| Novelli, A | 1 |
| Drago, F | 1 |
| Castori, M | 1 |
| Baban, A | 1 |
| Vogt, G | 1 |
| Kádasi, ĽL | 1 |
| Czeizel, E | 1 |
| Sivadorai, P | 1 |
| Cherninkova, S | 2 |
| Bouwer, S | 1 |
| Kamenarova, K | 1 |
| Angelicheva, D | 1 |
| Seeman, P | 1 |
| Hollingsworth, K | 1 |
| Mihaylova, V | 1 |
| Oscar, A | 1 |
| Dimitrova, G | 1 |
| Kaneva, R | 2 |
| Tournev, I | 2 |
| Kalaydjieva, L | 2 |
| Azmanov, DN | 1 |
| Dimitrova, S | 1 |
| Florez, L | 1 |
| Draganov, D | 1 |
| Morar, B | 1 |
| Saat, R | 1 |
| Juan, M | 1 |
| Arostegui, JI | 1 |
| Ganguly, S | 1 |
| Soodyall, H | 1 |
| Chakrabarti, S | 1 |
| Padh, H | 1 |
| López-Nevot, MA | 1 |
| Chernodrinska, V | 1 |
| Anguelov, B | 1 |
| Majumder, P | 1 |
| Angelova, L | 1 |
| Mackey, DA | 1 |
| Mendizabal, I | 1 |
| Valente, C | 1 |
| Gusmão, A | 1 |
| Alves, C | 1 |
| Gomes, V | 1 |
| Goios, A | 1 |
| Parson, W | 1 |
| Calafell, F | 1 |
| Alvarez, L | 1 |
| Amorim, A | 1 |
| Gusmão, L | 1 |
| Comas, D | 1 |
| Prata, MJ | 1 |
| Gencíkova, A | 5 |
| Gencík, A | 6 |
| Ferák, V | 4 |
| Gerinec, A | 2 |
| Plásilová, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of Gene, Inheritance Pattern and Genotype - Phenotype Correlations in South Korean Patients With Primary Congenital Glaucoma[NCT01020721] | 100 participants (Anticipated) | Observational | 2008-09-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for flumazenil and Glaucoma
| Article | Year |
|---|---|
Epidemiology and genetics of primary congenital glaucoma in Slovakia. Description of a form of primary congenital glaucoma in gypsies with autosomal-recessive inheritance and complete penetrance.
Topics: Age Factors; Child, Preschool; Cohort Studies; Cross-Sectional Studies; Female; Glaucoma; Humans; In | 1989 |
11 other studies available for flumazenil and Glaucoma
| Article | Year |
|---|---|
LTBP2-related "Marfan-like" phenotype in two Roma/Gypsy subjects with the LTBP2 homozygous p.R299X variant.
Topics: Adolescent; Child; Corneal Diseases; Ectopia Lentis; Eye Diseases, Hereditary; Female; Genetic Disea | 2019 |
[Homozygous E387K (1159G>A) mutation of the CYP1B1 gene in a Roma boy affected with primary congenital glaucoma. Case report].
Topics: Aryl Hydrocarbon Hydroxylases; Child, Preschool; Cytochrome P-450 CYP1B1; Genetic Counseling; Glauco | 2014 |
Genetic heterogeneity and minor CYP1B1 involvement in the molecular basis of primary congenital glaucoma in Gypsies.
Topics: Aryl Hydrocarbon Hydroxylases; Case-Control Studies; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzym | 2008 |
LTBP2 and CYP1B1 mutations and associated ocular phenotypes in the Roma/Gypsy founder population.
Topics: Adolescent; Adult; Aryl Hydrocarbon Hydroxylases; Child; Child, Preschool; Cytochrome P-450 CYP1B1; | 2011 |
Reconstructing the Indian origin and dispersal of the European Roma: a maternal genetic perspective.
Topics: DNA, Mitochondrial; Emigration and Immigration; Ethnicity; Founder Effect; Genetics, Population; Gla | 2011 |
Congenital glaucoma in Gypsies from Slovakia.
Topics: Adolescent; Adult; Child; Consanguinity; Czechoslovakia; Ethnicity; Female; Gene Frequency; Genes, R | 1982 |
Population genetic aspects of primary congenital glaucoma. II. Fitness, parental consanguinity, founder effect.
Topics: Consanguinity; Czechoslovakia; Ethnicity; Genetics, Population; Glaucoma; Humans; Roma | 1982 |
Population genetical aspects of primary congenital glaucoma. I. Incidence, prevalence, gene frequency, and age of onset.
Topics: Age Factors; Czechoslovakia; Ethnicity; Gene Frequency; Genetics, Population; Glaucoma; Humans; Roma | 1982 |
[Population-genetical characteristics of congenital glaucoma in Slovakia (author's transl)].
Topics: Consanguinity; Czechoslovakia; Glaucoma; Humans; Infant, Newborn; Roma | 1980 |
Genetic heterogeneity of congenital glaucoma.
Topics: Consanguinity; Czechoslovakia; Female; Genes, Recessive; Glaucoma; Humans; Male; Pedigree; Roma; Sex | 1980 |
[Molecular diagnosis of mutations responsible for recurrent and severe forms of primary congenital glaucoma].
Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Glaucoma; Hu | 1998 |