Page last updated: 2024-10-27

flumazenil and Genetic Predisposition

flumazenil has been researched along with Genetic Predisposition in 30 studies

Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.

Research Excerpts

ExcerptRelevanceReference
"Our aim is to compare the genetic susceptibility and possible effects of determinants associated with smoking behaviours in the Hungarian general (HG) and Roma populations."1.62Roma Socioeconomic Status Has a Higher Impact on Smoking Behaviour than Genetic Susceptibility. ( Ádány, R; Fiatal, S; Kósa, Z; Merzah, M; Natae, S; Pikó, P; Sándor, J, 2021)
"This study was designed to estimate the genetic susceptibility of the Hungarian Roma (HR) population to essential hypertension (EH) and compare it to that of the general (HG) population."1.56The genetic risk for hypertension is lower among the Hungarian Roma population compared to the general population. ( Ádány, R; Fiatal, S; Kósa, Z; Pikó, P; Sándor, J; Soltész, B, 2020)
"Besides modifiable risk factors, genetic susceptibility may also explain the high cardiovascular disease burden of the Roma population."1.51Genetic profiling revealed an increased risk of venous thrombosis in the Hungarian Roma population. ( Ádány, R; Fiatal, S; Kósa, Z; Pikó, P; Sándor, J, 2019)
"The aim of the study was to evaluate the genetic susceptibility of Roma to hazardous alcohol consumption compared to the Hungarian general population."1.46Distribution Characteristics and Combined Effect of Polymorphisms Affecting Alcohol Consumption Behaviour in the Hungarian General and Roma Populations. ( Ádány, R; Diószegi, J; Fiatal, S; Kósa, Z; McKee, M; Moravcsik-Kornyicki, Á; Sándor, J; Tóth, R, 2017)
"Our aim was to determine whether a genetic susceptibility contributes to the high prevalence of smoking among Roma in a study based on data collected from cross-sectional surveys."1.43High Prevalence of Smoking in the Roma Population Seems to Have No Genetic Background. ( Ádány, R; Fiatal, S; Kósa, Z; McKee, M; Moravcsik-Kornyicki, Á; Sándor, J; Tóth, R, 2016)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.33)18.2507
2000's7 (23.33)29.6817
2010's18 (60.00)24.3611
2020's4 (13.33)2.80

Authors

AuthorsStudies
Werissa, NA1
Piko, P6
Fiatal, S9
Kosa, Z8
Sandor, J8
Adany, R9
Llanaj, E1
Nagy, K3
Rácz, G1
János, S1
Soltész, B1
Pires, C1
Marques, IJ1
Dias, D1
Saramago, A1
Leite, V1
Cavaco, BM1
Merzah, M1
Natae, S1
Hubáček, JA1
Šedová, L1
Olišarová, V1
Adámková, V1
Adámek, V1
Tóthová, V1
Petrova, G1
Yaneva, N1
Hrbková, J1
Libik, M1
Savov, A1
Macek, M1
Szalai, R1
Magyari, L1
Matyas, P1
Duga, B2
Banfai, Z2
Szabo, A1
Kovesdi, E2
Melegh, B2
Tenorio, J1
Navas, P1
Barrios, E1
Fernández, L1
Nevado, J1
Quezada, CA1
López-Meseguer, M1
Arias, P1
Mena, R1
Lobo, JL1
Alvarez, C1
Heath, K1
Escribano-Subías, P1
Lapunzina, P1
Yus Cebrian, F1
Recasens Flores, Mdel V1
Izquierdo Álvarez, S1
Parra Salinas, I1
Rodriguez-Vigil Iturrate, C1
Diószegi, J1
Tóth, R2
Moravcsik-Kornyicki, Á2
McKee, M2
Mydlárová Blaščáková, M1
Blaščáková, Ľ1
Poráčová, J1
Mydlár, J1
Vašková, J1
Bernasovská, J2
Boroňová, I2
Petrejčíková, E2
Bernasovský, I2
Sumegi, K1
Melegh, BI1
Maasz, A1
Simko, V1
Ginter, E1
Fiore, M1
Nurden, AT1
Vinciguerra, C1
Nurden, P1
Pillois, X1
Juhász, E1
Béres, J1
Kanizsai, S1
Mačeková, S1
Gabriková, D1
Bôžiková, A1
Behulová, R1
Svíčková, P1
Soták, M1
Sovičová, A1
Carnogurská, J1
Sevilla, T1
Martínez-Rubio, D1
Márquez, C1
Paradas, C1
Colomer, J1
Jaijo, T1
Millán, JM1
Palau, F1
Espinós, C1
Minárik, G1
Ferák, V1
Feráková, E1
Ficek, A1
Poláková, H1
Kádasi, L1
Morar, B1
Gresham, D1
Angelicheva, D2
Tournev, I1
Gooding, R1
Guergueltcheva, V1
Schmidt, C1
Abicht, A1
Lochmuller, H1
Tordai, A1
Kalmar, L1
Nagy, M1
Karcagi, V1
Jeanpierre, M1
Herczegfalvi, A1
Beeson, D1
Venkataraman, V1
Warwick Carter, K1
Reeve, J1
de Pablo, R1
Kucinskas, V1
Kalaydjieva, L4
Schumacher, J1
Kaneva, R3
Jamra, RA1
Diaz, GO1
Ohlraun, S1
Milanova, V3
Lee, YA1
Rivas, F1
Mayoral, F1
Fuerst, R1
Flaquer, A1
Windemuth, C1
Gay, E1
Sanz, S1
González, MJ1
Gil, S1
Cabaleiro, F1
del Rio, F1
Perez, F1
Haro, J1
Kostov, C2
Chorbov, V1
Nikolova-Hill, A1
Stoyanova, V3
Onchev, G2
Kremensky, I2
Strauch, K1
Schulze, TG1
Nürnberg, P1
Gaebel, W1
Klimke, A1
Auburger, G1
Wienker, TF1
Propping, P1
Cichon, S1
Jablensky, A3
Rietschel, M1
Nöthen, MM1
Siváková, D1
Zacharová, M1
Gasparovic, J1
Raslová, K1
Wsólová, L1
Basistová, Z1
Blazícek, P1
Peterka, M1
Peterková, R1
Likovský, Z1
Fernández, O1
Fernández, V1
Martinez-Cabrera, V1
Mayorga, C1
Alonso, A1
León, A1
Arnal, C1
Hens, M1
Luque, G1
de Ramón, E1
Caballero, A1
Leyva, L1
MacGregor, S1
Vladimirova, R1
Aleksiev, S1
Angelova, M1
Loh, A1
Hallmayer, J2
Chakarova, CH1
Nikolova, A1
Belemezova, M1
Milenska, T1
Kirov, G1

Reviews

1 review available for flumazenil and Genetic Predisposition

ArticleYear
Short life expectancy and metabolic syndrome in Romanies (gypsies) in Slovakia.
    Central European journal of public health, 2010, Volume: 18, Issue:1

    Topics: Female; Genetic Predisposition to Disease; Humans; Life Expectancy; Male; Metabolic Syndrome; Phenot

2010

Trials

1 trial available for flumazenil and Genetic Predisposition

ArticleYear
High frequency of GJB2 mutation W24X among Slovak Romany (Gypsy) patients with non-syndromic hearing loss (NSHL).
    General physiology and biophysics, 2003, Volume: 22, Issue:4

    Topics: Child; Child, Preschool; Connexin 26; Connexins; Female; Genes, Dominant; Genetic Predisposition to

2003

Other Studies

28 other studies available for flumazenil and Genetic Predisposition

ArticleYear
SNP-Based Genetic Risk Score Modeling Suggests No Increased Genetic Susceptibility of the Roma Population to Type 2 Diabetes Mellitus.
    Genes, 2019, 11-19, Volume: 10, Issue:11

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Environmental Exposure; Fasting; Female; Genetic Pr

2019
Applicability of Obesity-Related SNPs and their Effect Size Measures Defined on Populations with European Ancestry for Genetic Risk Estimation among Roma.
    Genes, 2020, 05-06, Volume: 11, Issue:5

    Topics: Adult; Aged; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Europe; Female; Genetic Predisposition t

2020
The genetic risk for hypertension is lower among the Hungarian Roma population compared to the general population.
    PloS one, 2020, Volume: 15, Issue:6

    Topics: Adult; Alleles; Biomarkers; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposit

2020
A pathogenic variant in CHEK2 shows a founder effect in Portuguese Roma patients with thyroid cancer.
    Endocrine, 2021, Volume: 73, Issue:3

    Topics: Checkpoint Kinase 2; Ethnicity; Founder Effect; Genetic Predisposition to Disease; Humans; Male; Ped

2021
Roma Socioeconomic Status Has a Higher Impact on Smoking Behaviour than Genetic Susceptibility.
    International journal of environmental research and public health, 2021, 03-19, Volume: 18, Issue:6

    Topics: Female; Genetic Predisposition to Disease; Humans; Hungary; Male; Roma; Smoking; Social Class

2021
Genetic factors exist behind the high prevalence of reduced high-density lipoprotein cholesterol levels in the Roma population.
    Atherosclerosis, 2017, Volume: 263

    Topics: Adult; Atherosclerosis; Cardiovascular Diseases; Cholesterol, HDL; Cross-Sectional Studies; Female;

2017
Distinct Penetrance of Obesity-Associated Susceptibility Alleles in the Hungarian General and Roma Populations.
    Obesity facts, 2017, Volume: 10, Issue:5

    Topics: Adult; Aged; Alleles; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Ethnicity; Female; Gene Frequen

2017
Distribution of ADH1B genotypes predisposed to enhanced alcohol consumption in the Czech Roma/Gypsy population.
    Central European journal of public health, 2018, Volume: 26, Issue:4

    Topics: Alcohol Dehydrogenase; Alcohol Drinking; Czech Republic; Genetic Predisposition to Disease; Genotype

2018
Genetic profiling revealed an increased risk of venous thrombosis in the Hungarian Roma population.
    Thrombosis research, 2019, Volume: 179

    Topics: Adult; Cardiovascular Diseases; Female; Genetic Predisposition to Disease; Humans; Hungary; Male; Mi

2019
Identification of 99% of CFTR gene mutations in Bulgarian-, Bulgarian Turk-, and Roma cystic fibrosis patients.
    Molecular genetics & genomic medicine, 2019, Volume: 7, Issue:8

    Topics: Adolescent; Adult; Bulgaria; Child; Child, Preschool; Cohort Studies; Cystic Fibrosis; Cystic Fibros

2019
Genetic polymorphisms in promoter and intronic regions of CYP1A2 gene in Roma and Hungarian population samples.
    Environmental toxicology and pharmacology, 2014, Volume: 38, Issue:3

    Topics: Adult; Cytochrome P-450 CYP1A2; Female; Genetic Predisposition to Disease; Genotype; Healthy Volunte

2014
A founder EIF2AK4 mutation causes an aggressive form of pulmonary arterial hypertension in Iberian Gypsies.
    Clinical genetics, 2015, Volume: 88, Issue:6

    Topics: Adolescent; Adult; Base Sequence; Familial Primary Pulmonary Hypertension; Female; Founder Effect; G

2015
Combination of a triple alpha-globin gene with beta-thalassemia in a gypsy family: importance of the genetic testing in the diagnosis and search for a donor for bone marrow transplantation for one of their children.
    BMC research notes, 2016, Apr-14, Volume: 9

    Topics: alpha-Globins; beta-Thalassemia; Blood Donors; Bone Marrow Transplantation; Family Health; Female; G

2016
Distribution Characteristics and Combined Effect of Polymorphisms Affecting Alcohol Consumption Behaviour in the Hungarian General and Roma Populations.
    Alcohol and alcoholism (Oxford, Oxfordshire), 2017, Volume: 52, Issue:1

    Topics: Adult; Alcohol Drinking; Female; Genetic Predisposition to Disease; Humans; Hungary; Male; Middle Ag

2017
High Prevalence of Smoking in the Roma Population Seems to Have No Genetic Background.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2016, Volume: 18, Issue:12

    Topics: Adult; Aged; Cross-Sectional Studies; Family Characteristics; Female; Gene Frequency; Genetic Predis

2016
Relationship between A163G osteoprotegerin gene polymorphism and other osteoporosis parameters in Roma and non-Roma postmenopausal women in eastern Slovakia.
    Journal of clinical laboratory analysis, 2017, Volume: 31, Issue:5

    Topics: Case-Control Studies; Female; Genetic Predisposition to Disease; Humans; Osteoporosis; Osteoproteger

2017
Marked Differences of Haplotype Tagging SNP Distribution, Linkage, and Haplotype Profile of APOA5 Gene in Roma Population Samples.
    Pathology oncology research : POR, 2017, Volume: 23, Issue:4

    Topics: Adult; Apolipoprotein A-V; Cardiovascular Diseases; Female; Genetic Predisposition to Disease; Haplo

2017
Rapid diagnosis of the French gypsy mutation in Glanzmann thrombasthenia using high-resolution melting analysis.
    Thrombosis and haemostasis, 2010, Volume: 104, Issue:5

    Topics: DNA Mutational Analysis; France; Genetic Predisposition to Disease; Genetic Testing; Heterozygote; H

2010
The Consequence of a Founder Effect: CCR5-∆32, CCR2-64I and SDF1-3'A Polymorphism in Vlach Gypsy Population in Hungary.
    Pathology oncology research : POR, 2012, Volume: 18, Issue:2

    Topics: Chemokine CXCL12; Disease Progression; Ethnicity; Europe; Founder Effect; Gene Frequency; Genetic Pr

2012
Association of the FTO rs9939609 polymorphism with obesity in Roma/Gypsy population.
    American journal of physical anthropology, 2012, Volume: 147, Issue:1

    Topics: Adult; Aged; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Body Mass Index; Female; Genetic Predisp

2012
Genetics of the Charcot-Marie-Tooth disease in the Spanish Gypsy population: the hereditary motor and sensory neuropathy-Russe in depth.
    Clinical genetics, 2013, Volume: 83, Issue:6

    Topics: Adolescent; Adult; Cell Cycle Proteins; Charcot-Marie-Tooth Disease; Child; DNA Mutational Analysis;

2013
Mutation history of the roma/gypsies.
    American journal of human genetics, 2004, Volume: 75, Issue:4

    Topics: Chromosome Mapping; Cluster Analysis; DNA Mutational Analysis; Emigration and Immigration; Europe; F

2004
Genomewide scan and fine-mapping linkage studies in four European samples with bipolar affective disorder suggest a new susceptibility locus on chromosome 1p35-p36 and provides further evidence of loci on chromosome 4q31 and 6q24.
    American journal of human genetics, 2005, Volume: 77, Issue:6

    Topics: Bipolar Disorder; Bulgaria; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 4; Chromosomes, Hum

2005
Apolipoprotein E polymorphism in relation to plasma lipid levels and other risk factors of atherosclerosis in two ethnic groups from Slovakia.
    Collegium antropologicum, 2006, Volume: 30, Issue:2

    Topics: Adult; Apolipoproteins E; Atherosclerosis; Cholesterol; Female; Gene Frequency; Genetic Predispositi

2006
The lack of isolated palatal clefts in Czech Gypsies.
    Acta chirurgiae plasticae, 2006, Volume: 48, Issue:3

    Topics: Cleft Palate; Czech Republic; Female; Genetic Predisposition to Disease; Humans; Male; Retrospective

2006
Multiple sclerosis in Gypsies from southern Spain: prevalence, mitochondrial DNA haplogroups and HLA class II association.
    Tissue antigens, 2008, Volume: 71, Issue:5

    Topics: Adolescent; Adult; Aged; Alleles; DNA, Mitochondrial; Female; Genes, MHC Class II; Genetic Predispos

2008
Bipolar disorder in the Bulgarian Gypsies: genetic heterogeneity in a young founder population.
    American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2009, Mar-05, Volume: 150B, Issue:2

    Topics: Adolescent; Adult; Aged; Alleles; Bipolar Disorder; Bulgaria; Female; Founder Effect; Genetic Hetero

2009
A linkage study of affective disorders in two Bulgarian Gypsy families: results for candidate regions on chromosomes 18 and 21.
    Psychiatric genetics, 1998,Winter, Volume: 8, Issue:4

    Topics: Bipolar Disorder; Bulgaria; Centromere; Chromosomes, Human, Pair 18; Chromosomes, Human, Pair 21; Fe

1998