flumazenil has been researched along with Gangliosidosis, GM1 in 2 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Gangliosidosis, GM1: An autosomal recessive neurodegenerative disorder caused by the absence or deficiency of BETA-GALACTOSIDASE. It is characterized by intralysosomal accumulation of G(M1) GANGLIOSIDE and oligosaccharides, primarily in neurons of the central nervous system. The infantile form is characterized by MUSCLE HYPOTONIA, poor psychomotor development, HIRSUTISM, hepatosplenomegaly, and facial abnormalities. The juvenile form features HYPERACUSIS; SEIZURES; and psychomotor retardation. The adult form features progressive DEMENTIA; ATAXIA; and MUSCLE SPASTICITY. (From Menkes, Textbook of Child Neurology, 5th ed, pp96-7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sinigerska, I | 1 |
| Chandler, D | 1 |
| Vaghjiani, V | 1 |
| Hassanova, I | 1 |
| Gooding, R | 1 |
| Morrone, A | 1 |
| Kremensky, I | 1 |
| Kalaydjieva, L | 1 |
| Santamaria, R | 1 |
| Chabás, A | 1 |
| Coll, MJ | 1 |
| Miranda, CS | 1 |
| Vilageliu, L | 1 |
| Grinberg, D | 1 |
2 other studies available for flumazenil and Gangliosidosis, GM1
| Article | Year |
|---|---|
Founder mutation causing infantile GM1-gangliosidosis in the Gypsy population.
Topics: beta-Galactosidase; Founder Effect; Gangliosidosis, GM1; Humans; Infant; Point Mutation; Roma | 2006 |
Twenty-one novel mutations in the GLB1 gene identified in a large group of GM1-gangliosidosis and Morquio B patients: possible common origin for the prevalent p.R59H mutation among gypsies.
Topics: Adolescent; Adult; Base Sequence; beta-Galactosidase; Cells, Cultured; Child; Child, Preschool; Codo | 2006 |