flumazenil has been researched along with Fragile X Syndrome in 1 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Fragile X Syndrome: A condition characterized genotypically by mutation of the distal end of the long arm of the X chromosome (at gene loci FRAXA or FRAXE) and phenotypically by cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. INTELLECTUAL DISABILITY occurs in nearly all males and roughly 50% of females with the full mutation of FRAXA. (From Menkes, Textbook of Child Neurology, 5th ed, p226)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| D'Hulst, C | 1 |
| Heulens, I | 1 |
| Van der Aa, N | 1 |
| Goffin, K | 1 |
| Koole, M | 1 |
| Porke, K | 1 |
| Van De Velde, M | 1 |
| Rooms, L | 1 |
| Van Paesschen, W | 1 |
| Van Esch, H | 1 |
| Van Laere, K | 1 |
| Kooy, RF | 1 |
1 trial available for flumazenil and Fragile X Syndrome
| Article | Year |
|---|---|
Positron Emission Tomography (PET) Quantification of GABAA Receptors in the Brain of Fragile X Patients.
Topics: Adolescent; Adult; Animals; Brain; Female; Flumazenil; Fragile X Syndrome; Humans; Male; Mice; Middl | 2015 |