Page last updated: 2024-10-27

flumazenil and Fibromyalgia

flumazenil has been researched along with Fibromyalgia in 1 studies

Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.

Fibromyalgia: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)

Research Excerpts

ExcerptRelevanceReference
"Regional gray matter alterations in chronic pain, as detected with voxel-based morphometry of anatomical magnetic resonance images, are commonly interpreted to reflect neurodegeneration, but this assumption has not been tested."1.46Histological Underpinnings of Grey Matter Changes in Fibromyalgia Investigated Using Multimodal Brain Imaging. ( Araujo, D; Ceko, M; Daigle-Martel, A; Feier, NA; Fitzcharles, MA; Funck, T; Narayanan, S; Pomares, FB; Roy, S; Schweinhardt, P; Stikov, N; Thiel, A, 2017)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pomares, FB1
Funck, T1
Feier, NA1
Roy, S1
Daigle-Martel, A1
Ceko, M1
Narayanan, S1
Araujo, D1
Thiel, A1
Stikov, N1
Fitzcharles, MA1
Schweinhardt, P1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Investigation of the Effect of Initial Central Sensitization Severity on Treatment Response in Patients With Fibromyalgia[NCT05020600]40 participants (Anticipated)Observational2021-08-19Recruiting
Investigation of the Relationship Between Neuropathic Complaints and Central Sensitization in Patients With Fibromyalgia[NCT05701696]111 participants (Anticipated)Observational2023-01-16Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for flumazenil and Fibromyalgia

ArticleYear
Histological Underpinnings of Grey Matter Changes in Fibromyalgia Investigated Using Multimodal Brain Imaging.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017, 02-01, Volume: 37, Issue:5

    Topics: Aged; Body Water; Brain Chemistry; Chronic Pain; Female; Fibromyalgia; Flumazenil; Gray Matter; Huma

2017
Histological Underpinnings of Grey Matter Changes in Fibromyalgia Investigated Using Multimodal Brain Imaging.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017, 02-01, Volume: 37, Issue:5

    Topics: Aged; Body Water; Brain Chemistry; Chronic Pain; Female; Fibromyalgia; Flumazenil; Gray Matter; Huma

2017
Histological Underpinnings of Grey Matter Changes in Fibromyalgia Investigated Using Multimodal Brain Imaging.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017, 02-01, Volume: 37, Issue:5

    Topics: Aged; Body Water; Brain Chemistry; Chronic Pain; Female; Fibromyalgia; Flumazenil; Gray Matter; Huma

2017
Histological Underpinnings of Grey Matter Changes in Fibromyalgia Investigated Using Multimodal Brain Imaging.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017, 02-01, Volume: 37, Issue:5

    Topics: Aged; Body Water; Brain Chemistry; Chronic Pain; Female; Fibromyalgia; Flumazenil; Gray Matter; Huma

2017