Page last updated: 2024-10-27

flumazenil and Endotoxin Shock

flumazenil has been researched along with Endotoxin Shock in 1 studies

Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.

Research Excerpts

ExcerptRelevanceReference
"To assess the possible implication of the allosteric coupling of different modulatory sites at the GABA-A receptor complex in hepatic encephalopathy (HE), we investigated in autopsied frontal cortex of six cirrhotic patients and six appropriately-matched controls, the modulatory effects of the benzodiazepine site agonist flunitrazepam on the binding of [3H]muscimol and the effect of the neurosteroid site agonist allopregnanolone (5alpha-pregnan-3alpha-ol-20-one) on the binding of [3H]muscimol and [3H]flunitrazepam."3.72Normal coupling of brain benzodiazepine and neurosteroid modulatory sites on the GABA-A receptor complex in human hepatic encephalopathy. ( Ahboucha, S; Butterworth, RF; Chatauret, N; Desjardins, P; Pomier-Layrargues, G, 2003)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahboucha, S1
Desjardins, P1
Chatauret, N1
Pomier-Layrargues, G1
Butterworth, RF1

Other Studies

1 other study available for flumazenil and Endotoxin Shock

ArticleYear
Normal coupling of brain benzodiazepine and neurosteroid modulatory sites on the GABA-A receptor complex in human hepatic encephalopathy.
    Neurochemistry international, 2003, Volume: 43, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Brain; Female; Flumazenil; Flunitrazepam; Hepatic Encephalopathy; Hu

2003