flumazenil has been researched along with Emergencies in 12 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Emergencies: Situations or conditions requiring immediate intervention to avoid serious adverse results.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Flumazenil is an important adjunct to the diagnosis and treatment of benzodiazepine toxicity." | 6.39 | Reappraisal of the "coma cocktail". Dextrose, flumazenil, naloxone, and thiamine. ( Doyon, S; Roberts, JR, 1994) |
| "Flumazenil was injected intravenously as a 0." | 5.29 | Diagnostic and therapeutic utility of flumazenil in comatose patients with drug overdose. ( Chern, TL; Deng, JF; Hu, SC; Lee, CH, 1993) |
| " When sedation with benzodiazepines is carried out, the specific antagonist, flumazenil should always be available for use in emergencies such as accidental oversedation, iatrogenic overdose or paradoxical reactions." | 3.69 | Use of inhalational and intravenous sedation in dentistry. ( Rodrigo, MR, 1997) |
| "Flumazenil acts as an antidote for pharmacological and toxic effects due to benzodiazepines." | 2.67 | Efficacy of flumazenil in acute alcohol intoxication: double blind placebo-controlled evaluation. ( Askenasi, R; Lheureux, P, 1991) |
| "Flumazenil is an important adjunct to the diagnosis and treatment of benzodiazepine toxicity." | 2.39 | Reappraisal of the "coma cocktail". Dextrose, flumazenil, naloxone, and thiamine. ( Doyon, S; Roberts, JR, 1994) |
| "Flumazenil has been reported to reverse the CNS effects of zolpidem." | 1.39 | Pediatric zolpidem ingestion demonstrating zero-order kinetics treated with flumazenil. ( Carstairs, SD; Negus, E; Thornton, SL, 2013) |
| "Flumazenil was injected intravenously as a 0." | 1.29 | Diagnostic and therapeutic utility of flumazenil in comatose patients with drug overdose. ( Chern, TL; Deng, JF; Hu, SC; Lee, CH, 1993) |
| "Flumazenil was injected intravenously first in a regimen of 0." | 1.28 | [Flumazenil as an emergency management of patients with acute mental disorder]. ( Chern, TL; Deng, JF; Hu, SC; Lee, CH, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 7 (58.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Setlakwe, EL | 1 |
| Johnson, AL | 1 |
| Thornton, SL | 1 |
| Negus, E | 1 |
| Carstairs, SD | 1 |
| Jeske, AH | 1 |
| Redden, RJ | 1 |
| Doyon, S | 1 |
| Roberts, JR | 1 |
| Shibata, T | 1 |
| Kubota, N | 1 |
| Yokoyama, H | 1 |
| Chern, TL | 2 |
| Hu, SC | 2 |
| Lee, CH | 2 |
| Deng, JF | 2 |
| Rodrigo, MR | 1 |
| Roberge, RJ | 1 |
| Lin, E | 1 |
| Krenzelok, EP | 1 |
| Buylaert, WA | 1 |
| Lheureux, P | 1 |
| Askenasi, R | 1 |
| Baehrendtz, S | 1 |
| Höjer, J | 1 |
4 reviews available for flumazenil and Emergencies
| Article | Year |
|---|---|
Narcotic/sedative receptor antagonists.
Topics: Anesthesia, Dental; Anti-Anxiety Agents; Binding, Competitive; Conscious Sedation; Drug Interactions | 1993 |
Reappraisal of the "coma cocktail". Dextrose, flumazenil, naloxone, and thiamine.
Topics: Animals; Coma; Emergencies; Flumazenil; Glucose; Humans; Naloxone; Thiamine | 1994 |
Coma induced by intoxication.
Topics: Accidental Falls; Alcohol-Induced Disorders, Nervous System; Alcoholic Intoxication; Antidotes; Brai | 2000 |
Flumazenil in self-induced benzodiazepine poisoning.
Topics: Anesthesia; Benzodiazepines; Emergencies; Flumazenil; Humans; Receptors, GABA-A | 1988 |
2 trials available for flumazenil and Emergencies
| Article | Year |
|---|---|
Efficacy of flumazenil in acute alcohol intoxication: double blind placebo-controlled evaluation.
Topics: Adolescent; Adult; Aged; Alcoholic Intoxication; Benzodiazepines; Coma; Double-Blind Method; Drug Ov | 1991 |
Flumazenil in self-induced benzodiazepine poisoning.
Topics: Anesthesia; Benzodiazepines; Emergencies; Flumazenil; Humans; Receptors, GABA-A | 1988 |
7 other studies available for flumazenil and Emergencies
| Article | Year |
|---|---|
Acute encephalopathy in a 2-year-old pot-bellied pig following accidental intoxication with clonazepam.
Topics: Acute Febrile Encephalopathy; Animals; Antidotes; Clonazepam; Diagnosis, Differential; Drug-Related | 2017 |
Pediatric zolpidem ingestion demonstrating zero-order kinetics treated with flumazenil.
Topics: Antidotes; Central Nervous System Depressants; Child; Coma; Down Syndrome; Drug Overdose; Emergencie | 2013 |
[A pregnant woman with convulsion treated with diazepam which was reversed with flumazenil just prior to cesarean section].
Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Cesarean Section; Diazepam; Eclampsia; Emergenc | 1994 |
Diagnostic and therapeutic utility of flumazenil in comatose patients with drug overdose.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzodiazepines; Coma; Drug Overdose; Emergencies; Femal | 1993 |
Use of inhalational and intravenous sedation in dentistry.
Topics: Accidents; Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthesia, Local; A | 1997 |
Flumazenil reversal of carisoprodol (Soma) intoxication.
Topics: Antidotes; Carisoprodol; Central Nervous System; Emergencies; Female; Flumazenil; GABA Modulators; H | 2000 |
[Flumazenil as an emergency management of patients with acute mental disorder].
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Emergencies; Female; Flumazenil; Humans; Male; Middle | 1992 |