flumazenil has been researched along with Disease Exacerbation in 14 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
| Excerpt | Relevance | Reference |
|---|---|---|
| "PET allowed prediction of malignant MCA infarction within the time window suggested for hemicraniectomy." | 2.71 | Prediction of malignant course in MCA infarction by PET and microdialysis. ( Bosche, B; Brinker, G; Dohmen, C; Graf, R; Heiss, WD; Kracht, L; Neveling, M; Sobesky, J; Staub, F, 2003) |
| "Therapeutic management in hepatic encephalopathy depends on its etiology as well as progression degree." | 2.41 | [Therapeutic management of hepatic encephalopathy]. ( Helewski, KJ; Konecki, JJ; Kowalczyk-Ziomek, GI, 2002) |
| "Treatment with alprazolam was found to reverse partially the adverse effects of postinoculation stress, and also to inhibit the beneficial effects of the preinoculation administration of stress on tumor development." | 1.29 | Effects of alprazolam on the development of Moloney sarcoma virus-induced tumors in stressed mice. ( Balboa, JL; Fernández-Rial, JC; Freire-Garabal, M; García-Vallejo, L; Núñez-Iglesias, MJ; Rey-Méndez, M, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 8 (57.14) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vivash, L | 1 |
| Gregoire, MC | 1 |
| Bouilleret, V | 1 |
| Berard, A | 1 |
| Wimberley, C | 1 |
| Binns, D | 1 |
| Roselt, P | 1 |
| Katsifis, A | 1 |
| Myers, DE | 1 |
| Hicks, RJ | 1 |
| O'Brien, TJ | 1 |
| Dedeurwaerdere, S | 1 |
| Horino, A | 1 |
| Kawawaki, H | 1 |
| Fukuoka, M | 1 |
| Tsuji, H | 1 |
| Hattori, Y | 1 |
| Inoue, T | 1 |
| Nukui, M | 1 |
| Kuki, I | 1 |
| Okazaki, S | 1 |
| Tomiwa, K | 1 |
| Hirose, S | 1 |
| Yamauchi, H | 1 |
| Nishii, R | 1 |
| Higashi, T | 1 |
| Kagawa, S | 1 |
| Fukuyama, H | 1 |
| Heiss, WD | 3 |
| Helewski, KJ | 1 |
| Kowalczyk-Ziomek, GI | 1 |
| Konecki, JJ | 1 |
| Dohmen, C | 1 |
| Bosche, B | 1 |
| Graf, R | 1 |
| Staub, F | 1 |
| Kracht, L | 1 |
| Sobesky, J | 1 |
| Neveling, M | 1 |
| Brinker, G | 1 |
| Turner, MR | 2 |
| Hammers, A | 2 |
| Al-Chalabi, A | 2 |
| Shaw, CE | 2 |
| Andersen, PM | 2 |
| Brooks, DJ | 2 |
| Leigh, PN | 2 |
| Osei-Lah, AD | 1 |
| Mills, KR | 1 |
| Freire-Garabal, M | 1 |
| Núñez-Iglesias, MJ | 1 |
| Balboa, JL | 1 |
| Fernández-Rial, JC | 1 |
| García-Vallejo, L | 1 |
| Rey-Méndez, M | 1 |
| Kracht, LW | 1 |
| Thiel, A | 1 |
| Grond, M | 1 |
| Pawlik, G | 1 |
| Matheja, P | 1 |
| Lüdemann, P | 1 |
| Kuwert, T | 1 |
| Weckesser, M | 1 |
| Kellinghaus, C | 1 |
| Weitemeyer, L | 1 |
| Diehl, B | 1 |
| Schuierer, G | 1 |
| Ringelstein, EB | 1 |
| Schober, O | 1 |
| Chamova, T | 1 |
| Guergueltcheva, V | 1 |
| Gospodinova, M | 1 |
| Krause, S | 1 |
| Cirak, S | 1 |
| Kaprelyan, A | 1 |
| Angelova, L | 1 |
| Mihaylova, V | 1 |
| Bichev, S | 1 |
| Chandler, D | 2 |
| Naydenov, E | 1 |
| Grudkova, M | 1 |
| Djukmedzhiev, P | 1 |
| Voit, T | 2 |
| Pogoryelova, O | 1 |
| Lochmüller, H | 1 |
| Goebel, HH | 1 |
| Bahlo, M | 1 |
| Kalaydjieva, L | 2 |
| Tournev, I | 2 |
| Juhász, E | 1 |
| Béres, J | 1 |
| Kanizsai, S | 1 |
| Nagy, K | 1 |
| Angelicheva, D | 1 |
| Heather, L | 1 |
| Gooding, R | 1 |
| Gresham, D | 1 |
| Yanakiev, P | 1 |
| de Jonge, R | 1 |
| Baas, F | 1 |
| Dye, D | 1 |
| Karagyozov, L | 1 |
| Savov, A | 1 |
| Blechschmidt, K | 1 |
| Keats, B | 1 |
| Thomas, PK | 1 |
| King, RH | 1 |
| Starr, A | 1 |
| Nikolova, A | 1 |
| Colomer, J | 1 |
| Ishpekova, B | 1 |
| Urtizberea, JA | 1 |
| Merlini, L | 1 |
| Butinar, D | 1 |
| Chabrol, B | 1 |
| Baethmann, M | 1 |
| Nedkova, V | 1 |
| Corches, A | 1 |
2 reviews available for flumazenil and Disease Exacerbation
| Article | Year |
|---|---|
The ischemic penumbra: how does tissue injury evolve?
Topics: Animals; Brain; Brain Edema; Brain Ischemia; Cats; Cerebral Infarction; Cerebrovascular Circulation; | 2012 |
[Therapeutic management of hepatic encephalopathy].
Topics: Anti-Bacterial Agents; Disease Progression; Flumazenil; Hepatic Encephalopathy; Humans; Lactulose; L | 2002 |
2 trials available for flumazenil and Disease Exacerbation
| Article | Year |
|---|---|
Prediction of malignant course in MCA infarction by PET and microdialysis.
Topics: Biomarkers; Blood Flow Velocity; Brain Edema; Carbon Radioisotopes; Cerebrovascular Circulation; Dis | 2003 |
Penumbral probability thresholds of cortical flumazenil binding and blood flow predicting tissue outcome in patients with cerebral ischaemia.
Topics: Aged; Blood Flow Velocity; Brain Ischemia; Cerebral Cortex; Cerebrovascular Circulation; Disease Pro | 2001 |
10 other studies available for flumazenil and Disease Exacerbation
| Article | Year |
|---|---|
In vivo measurement of hippocampal GABAA/cBZR density with [18F]-flumazenil PET for the study of disease progression in an animal model of temporal lobe epilepsy.
Topics: Animals; Disease Progression; Epilepsy, Temporal Lobe; Flumazenil; Hippocampus; Male; Models, Animal | 2014 |
A case of succinic semialdehyde dehydrogenase deficiency with status epilepticus and rapid regression.
Topics: Amino Acid Metabolism, Inborn Errors; Atrophy; Brain; Developmental Disabilities; Diffusion Magnetic | 2016 |
Hemodynamic compromise as a cause of internal border-zone infarction and cortical neuronal damage in atherosclerotic middle cerebral artery disease.
Topics: Aged; Carbon Radioisotopes; Cerebral Arteries; Cerebral Cortex; Cerebrovascular Circulation; Disease | 2009 |
Distinct cerebral lesions in sporadic and 'D90A' SOD1 ALS: studies with [11C]flumazenil PET.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Carbon Radioisotopes; Cerebral Cortex; Disease Progressi | 2005 |
Abnormal cortical excitability in sporadic but not homozygous D90A SOD1 ALS.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Case-Control Studies; Cerebral Cortex; Disease Progressi | 2005 |
Effects of alprazolam on the development of Moloney sarcoma virus-induced tumors in stressed mice.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Disease Progression; Female; Flumazenil; GABA Modulators; | 1996 |
Disturbed benzodiazepine receptor function at the onset of temporal lobe epilepsy--lomanzenil-binding in de-novo TLE.
Topics: Adolescent; Adult; Binding Sites; Disease Progression; Epilepsy, Temporal Lobe; Female; Flumazenil; | 2001 |
GNE myopathy in Roma patients homozygous for the p.I618T founder mutation.
Topics: Adolescent; Adult; Child; Disease Progression; Distal Myopathies; Female; Follow-Up Studies; Founder | 2015 |
The Consequence of a Founder Effect: CCR5-∆32, CCR2-64I and SDF1-3'A Polymorphism in Vlach Gypsy Population in Hungary.
Topics: Chemokine CXCL12; Disease Progression; Ethnicity; Europe; Founder Effect; Gene Frequency; Genetic Pr | 2012 |
Hereditary motor and sensory neuropathy--Lom (HMSNL): refined genetic mapping in Romani (Gypsy) families from several European countries.
Topics: Adolescent; Adult; Child; Chromosome Mapping; Disease Progression; DNA Mutational Analysis; Europe; | 2000 |