flumazenil has been researched along with Creutzfeldt-Jakob Syndrome in 3 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Creutzfeldt-Jakob Syndrome: A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aguglia, U | 2 |
| Oliveri, RL | 2 |
| Gambardella, A | 2 |
| Quattrone, A | 2 |
| Talerico, G | 1 |
| Zappia, M | 1 |
| De Sarro, GB | 1 |
| Itoh, Y | 1 |
| Amano, T | 1 |
| Shimizu, T | 1 |
| Hashimoto, J | 1 |
| Kubo, A | 1 |
| Fukuuchi, Y | 1 |
3 other studies available for flumazenil and Creutzfeldt-Jakob Syndrome
| Article | Year |
|---|---|
Functional integrity of benzodiazepine receptors of the geniculo-striate visual pathways in Creutzfeldt-Jakob disease. A pharmacological evoked potential study.
Topics: Creutzfeldt-Jakob Syndrome; Diazepam; Evoked Potentials, Visual; Flumazenil; Humans; Male; Middle Ag | 1993 |
Functional preservation of benzodiazepine receptors of the primary somatosensory cortex in Creutzfeldt-Jakob disease: a pharmacologic-evoked potential study.
Topics: Aged; Creutzfeldt-Jakob Syndrome; Diazepam; Electroencephalography; Evoked Potentials, Somatosensory | 1996 |
Single-photon emission computed tomography image of benzodiazepine receptors in a patient with Creutzfeldt-Jakob disease.
Topics: Brain; Brain Chemistry; Cerebellar Ataxia; Creutzfeldt-Jakob Syndrome; Female; Flumazenil; Humans; M | 1998 |