flumazenil has been researched along with Convulsive Generalized Seizure Disorder in 9 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Most PET receptor studies in idiopathic generalized epilepsy conducted to date include only small numbers of patients and should be interpreted with caution." | 2.42 | Flumazenil positron emission tomography and other ligands for functional imaging. ( Hammers, A, 2004) |
| "Idiopathic generalized epilepsy, with a marked familial character, has not been reported to date in Bulgarian Gypsies." | 1.34 | Familial generalized epilepsy in Bulgarian Roma. ( Genton, P; Guergueltcheva, V; Jamali, S; Lathrop, M; Petkov, R; Radionova, M; Raycheva, M; Royer, B; Szepetowski, P; Tournev, I; Velizarova, R; Yonova, M, 2007) |
| "Five patients with idiopathic generalized epilepsy (IGE) were studied at rest and during absence seizures with [11C]flumazenil and positron emission tomography (PET)." | 1.29 | Benzodiazepine-GABAA receptor binding during absence seizures. ( Brooks, DJ; Cunningham, VJ; Duncan, JS; Fish, DR; Lammertsma, AA; Prevett, MC, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hammers, A | 1 |
| Fedi, M | 1 |
| Berkovic, SF | 1 |
| Marini, C | 1 |
| Mulligan, R | 1 |
| Tochon-Danguy, H | 1 |
| Reutens, DC | 1 |
| Prevett, MC | 1 |
| Lammertsma, AA | 1 |
| Brooks, DJ | 2 |
| Cunningham, VJ | 2 |
| Fish, DR | 1 |
| Duncan, JS | 2 |
| Reisner-Keller, LA | 1 |
| Pham, Z | 1 |
| Decoo, D | 1 |
| Destée, A | 1 |
| Koepp, MJ | 1 |
| Richardson, MP | 1 |
| Savic, I | 1 |
| Morar, B | 1 |
| Zhelyazkova, S | 1 |
| Azmanov, DN | 1 |
| Radionova, M | 2 |
| Angelicheva, D | 1 |
| Guergueltcheva, V | 2 |
| Kaneva, R | 1 |
| Scheffer, IE | 1 |
| Tournev, I | 2 |
| Kalaydjieva, L | 1 |
| Sander, JW | 1 |
| Royer, B | 1 |
| Szepetowski, P | 1 |
| Velizarova, R | 1 |
| Yonova, M | 1 |
| Lathrop, M | 1 |
| Jamali, S | 1 |
| Petkov, R | 1 |
| Raycheva, M | 1 |
| Genton, P | 1 |
3 reviews available for flumazenil and Convulsive Generalized Seizure Disorder
| Article | Year |
|---|---|
Flumazenil positron emission tomography and other ligands for functional imaging.
Topics: Brain; Epilepsies, Partial; Epilepsy, Generalized; Flumazenil; GABA Modulators; Humans; Ligands; Neu | 2004 |
PET studies in epilepsy.
Topics: Brain; Carbon Radioisotopes; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fentanyl; Flumaze | 1997 |
PET: central benzodiazepine neuroreceptor mapping in generalized epilepsies.
Topics: Cerebral Cortex; Epilepsy, Generalized; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Humans | 2000 |
6 other studies available for flumazenil and Convulsive Generalized Seizure Disorder
| Article | Year |
|---|---|
A GABAA receptor mutation causing generalized epilepsy reduces benzodiazepine receptor binding.
Topics: Adult; Aged; Brain Mapping; Epilepsy, Generalized; Female; Flumazenil; GABA Modulators; Gyrus Cingul | 2006 |
Benzodiazepine-GABAA receptor binding during absence seizures.
Topics: Adolescent; Adult; Age of Onset; Brain; Carbon Radioisotopes; Cerebrovascular Circulation; Child; Ep | 1995 |
Oral flumazenil in the treatment of epilepsy.
Topics: Administration, Oral; Clinical Trials as Topic; Diazepam; Drug Therapy, Combination; Epilepsy; Epile | 1995 |
Central benzodiazepine/gamma-aminobutyric acid A receptors in idiopathic generalized epilepsy: an [11C]flumazenil positron emission tomography study.
Topics: Adult; Analysis of Variance; Brain; Carbon Radioisotopes; Cerebellum; Cerebral Cortex; Epilepsy, Gen | 1997 |
A novel GEFS+ locus on 12p13.33 in a large Roma family.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Carrier Proteins; Chromosomes, Human, Pair 12; Co | 2011 |
Familial generalized epilepsy in Bulgarian Roma.
Topics: Adolescent; Adult; Anticonvulsants; Bulgaria; Child; Child, Preschool; DNA; Electroencephalography; | 2007 |